Doctor insights on:
What Is The Difference Between Carcinoma And Sarcoma
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Different cancers: Sarcomas are very rare cancers that arise from bone, muscle, nerves, blood vessels or other connective tissues. Carcinomas are very common cancers that tend form glands. Most common examples are breast cancer, lung cancer, colon cancer, prostate cancer and renal (kidney) cancer, among others. ...Read moreSee 1 more doctor answer
Different origins: The suffix "oma" signifies a malignant lesion Since the body has various sources from which cellular and organ structures are derived different tumor types similarly arise. The epithelial cells comprising the tracheobronchial tree and those cells that comprise the lining of the GI tract form malignant lesions known as carcinomas. Those supportive cells of muscle, bone form sarcomas. ...Read more
Derivation: sarcomas arise from supportive tissues of the body. They are found in and derived from muscle, fibrous tissue and fascia, fat, nerve, blood vessel and bone. Spread is to liver and lung. Carcinomas arise from secretory and epithelial membrane spreading first to regional nodes as seen with breast, colon and lung. They respond differently to chemo. ...Read more
See below: Invasive carcinoma means the cancer has grown to the extent that it starts invading into surrounding tissue such as fat, fibrous tissue, lymphatics etc. Sarcoma is one type of cancer that arises from soft or connective tissue such as mucle, bone, blood vessels etc. It behaves differently from carcinoma which comes from lining of skin, ducts or internal organs. Surgery is primary treatment. ...Read more
Usually random: Sarcomas are bone and soft tissue cancers. Generally, these occur because of random events in most patients. However things like radiation exposure can increase the risk of bone and soft tissue sarcomas particularly with higher dose radiation like used for treatment of other cancers. There are some genetic diseases like li-fraumeni that can result in getting a sarcoma and other cancers. ...Read moreSee 1 more doctor answer
Yes they are: Sarcomas are embryo logically mesodermal tumors like muscle bones , supporting tissue etc, if they are not detected early and not treated they are just as bad as carcinomas, . They tend to spread by blood stream not by lymphatics , usually resistant to radiation. ...Read moreSee 1 more doctor answer
Terminology: Forget the arcana of germ layers in cancer nomenclature. Sarcomas are cancers that have, for their cell of origin, a connective tissue cell -- bone, cartilage, undifferented mesenchyme, fat, smooth / striated muscle, endothelium. By convention, cancers arising from blood elements, lymphocytes and mesothelium are given non-sarcoma names. ...Read more
No: Chemotherapy does not make sarcoma worse. However, some kinds of sarcomas are quite resistant to many chemotherapies. Other types like ewing's sarcoma, osteosarcoma, rhabdomyosarcoma, and even synovial sarcoma can respond to chemotherapy very well and chemo is an essential part of the the cure of these diseases. There are also new drugs available that can slow the growth of more resistant types. ...Read moreSee 1 more doctor answer
Very: It will invariably kill if it is untreated. If it has spread to the lungs, we presently have no cure. If it has not, with today's therapy (surgery; the value of radiation and/or chemotherapy, depending on the stage of tumor and type of treatment) more than 50% of patients survive 5-years, the majority of these disease-free. Good luck. ...Read moreSee 1 more doctor answer
Sometimes: Sarcomas cover a large group of tumors that arise from soft tissues (skeletal muscle, smooth muscle, bone, cartilage, blood vessels, nerves, fat, connective tissue). Just below the skin, all of these structures can become malignant and give rise to a sarcoma. A biopsy with microscopic examination (by a pathologist) is required, with special studies usually required to confirm the diagnosis. ...Read moreSee 2 more doctor answers
It used to be seen: In elderly men of mediterranean origin, a purple raised lesions most commonly on extremities, and it was quite rare. However, it became the hallmark skin finding in the early aids epidemic, as immune systems deteriorated, these lesion occurred all over bodies. Interestingly, as immune systems recovered, many of these lesion involute indicating a strong importance of immunity. ...Read moreSee 2 more doctor answers
Tough question: The first therapy is haart, highly active antiretroviral therapy. Once the the viral load is down, commonly the kaposi's sarcoma resolves. If it does not, then Paclitaxel is a good chemotherapy for this. The length of therapy depends on the response. Hope this helps. ...Read moreSee 1 more doctor answer
Ewing sarcoma: Ewing sarcoma is a very treatable bone and soft tissue sarcoma that generally affects adolescents and young adults. The positive news is that in its localized (non-metastatic) setting it is very treatable and curable (about 70% survival) with appropriate chemotherapy, surgery and/or radiation therapy. In its metastatic stage, ewing sarcoma is more difficult to treat and the prognosis is poor. ...Read moreSee 1 more doctor answer
No. : Sarcomas of bone (osteosarcoma, ewing's etc..) are almost incurable without chemotherapy and have a very good chance of cure with chemotherapy. It is not clear if chemotherapy helps for soft tissue sarcomas, though. In some studies it helps, in others it doesn't, but it certainly doesn't make things worse. Each situation is different, so ask your oncologist. ...Read more
Yes. It is a: Disease affecting young men, "always" under 30, teens most common, tending to arise in bones, and metastases to other bones and lung. When caught in the originating bone, usually with pain, or even fracture, before metastasis, it can be cured. Once metastatic, cure is not likely. Ergo, it can be fatal. ...Read moreSee 2 more doctor answers
By definition, it is malignant (i.e., being locally invasive and at least theoreticlally capable of metastasizing), and arises from / mimics muscle or connective tissue elements that are not marrow or immune / white cells. The sarcomas are a tremendously varied and troublesome family of tumors, though thankfully less common than carcinomas and the leukemia / ...Read more
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