Doctor insights on:
What Is The Difference Between Acute And Chronic Leukemia
Everything: Acute leukemia is presented with the presence of significant level of a very immature blood cells in the circulation and increase level in the bone marrow. It is a very agressive and life threatening. Without treatment people die within weeks and few months only. Chronic leukemia- is progressing slower than acute leukemia. Chronic leukemia can transform into acute leukemia sometimes. ...Read more
Leukemia is a malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more
Various : Acute leukemia can lead to symptoms (bleeding, fever, infection, weakness) very quickly and requires treatment soon to avoid serious consequences including death. Chronic leukemias are more indolent may take awhile before causing symptoms often diagnose incidentally on a blood count. Treatment depends on the kind of leukemia: myeloid-treated soon to avoid becoming acute; lymphoid-could be watched. ...Read more
I'm just wondering, if you are diagnosed with a form of chronic leukemia can it change to an acute leukemia?
Yes, sometimes: There are two separate types of chronic leukemia;these go by the names CML and cll. They follow a separate course and can have a long course of disease. CML often ends up as acute leukemia(called blastic change which is a type of acute leukemia bearing poor survival once this transformation has taken place. Fortunately the risk of this happening is much reduced with the modern treatments for cml. ...Read more
What are pros cons of drug procrit (epoetin alfa) to treat 88 year-old man whose chronic leukemia is now becoming acute where he needs transfusions every two weeks?
Limited value: Procrit (epoetin alfa) is commonly used in patients with cancer. But it is not always effective as it helps to raise red cell counts(hb) in most pateints but takes 4-6 weeks before it has any visible benefit.. A patient with acute leukemia has more urgent needs which are best met with a blood transfusion as needed. But his age is against him to achieve much benefit from anything further that can be done for him. ...Read moreSee 1 more doctor answer
What is success rate of using prednisone in treatment of 88 year-old man whose chronic leukemia is now becoming acute with transfusions every 2 weeks?
Not significant: I am sorry, but i don't think that by itself will work. I do not know what is the reason to give you Prednisone for acute leukemia. If that is given in conjunction to other kind of therapy-that would make more sense. Please discuss with your oncologist further. Dacogen (decitabine) is something you can consider ...Read more
Blood work etc: You would need at least- blood work. Imaging scan for abdomen would be needed in certain chronic leukemia ( cml) to evaluate spleen or if there is other indication ( such as presence of abdominal pain etc); a bone marrow biopsy will be needed in certain case of chronic leukemia. Please discuss further in detail with your hematologist/ oncologist. Read more at www.Cancer.Net ; www.Lls.Org. ...Read moreSee 1 more doctor answer
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