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What Is The Cause Of Hyperpigmentation Is It Related To High Levels Of Acth
Multiple reasons: Hyperpigmentation may be caused by sun damage, inflammation, or other skin injuries, including those related to acne vulgaris. In cushing's disease, there is excessive adrenocorticotropic hormone (acth) production, which leads to hyperpigmentation because msh (melanocyte stimulating hormone) production is a byproduct of acth synthesis from proopiomelanocortin (pomc). ...Read moreSee 1 more doctor answer
It is one of several pituitary hormones - acth for short (the others control the thyroid gland, gonad glands, and others) that controls adrenal gland function in primarily making the hormone called cortisol (not to be confused with "adrenaline"), though the adrenal gland also ...Read more
What could cause someone with a diagnosed history of 2nd addison's to suddenly havea high acth and high cortisol levels?
High cortisol level in evening , high acth level131pg...Mild hypertension.., no mass in suprarenal gland , cuahing appearance..Cause?
Possible pituitary: Having a high cortisol with a high acth level is indicative of acth dependent cushings disease. This is a rare disorder due to a pituitary adenoma making too much acth. You may or may not be able to see an abnormality on ct scan or MRI of the pituitary. You should do Dexamethasone suppression testing to confirm the diagnosis. Sometimes the acth is coming from a source outside of the pituitary. ...Read more
Need more info: Hi. Have you been diagnosed with Cushing's? If not, it means nothing. Illness and physiologic stress can drive up ACTH, and ACTH shows diurnal variation. Without knowing the time of day it was drawn and your physiologic circumstances, it means nothing. And yet, the doc who ordered it was considering something, so really don't have enough info to say. Good luck! ...Read more
CAH: There is a disorder called congenital adrenal hyperplasia, that can appear in adults (late onset), in which there are symptoms similar to PCOS with irregular periods, excess hair growth, weight gain. 17OH progesterone levels will be high but other levels can be normal. It is treated with low dose corticosteroid. You should see an endocrinologist for diagnosis. ...Read more
Life: Spot acth levels fluctuate tremendously just from the transient stresses of living, or even without. Even if elevated from disease, they'll fluctuate wildly. This is why we try to suppress them and if we can't, disease is likely. ...Read more
Probably not: But you need to see your doctor immediately. ...Read more
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