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Doctor insights on: What Is Sulfasalazin

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What is sulfasalazin?

Sulfasalazine: Generic name for azulfadine, used in treating inflammatory bowel disease, such as chrons disease or ulcerative colitis. ...Read more

Dr. Jeremy Adler
112 doctors shared insights

Sulfasalazine (Definition)

Sulfasalazine ...Read more


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Does anyone have problems with this drug, sulfasalazine?

Yes, sometimes: Up until the 80's we only had sulasalazine for uc. The main problems were headace and some rqshes usually due to the sulfapyridine moiety. Pure Mesalamine drugs such as asacol, lialda, Balsalazide and others do not contain the sulapyridine part and therefore don't have as many problems with the drug. However sulfasalazine is still cheap and useful and should not be ignored. ...Read more

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How long does sulfasalazine stay in your system?

How long does sulfasalazine stay in your system?

It depends: Sulfasalazine has a half life of 7.6 hr on avg. It's a short acting medication which is why it requires every 6-12 hour dosing. A drug is cleared from system entirely after 10 half lives so the drug should theoretically be cleared in 76 hrs or a little over 3 days. The metabolite of sulfasalazine, sulfapyridine has a half life of 10.4-14.8 h so it's cleared in 148 hrs from system ...Read more

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Will sulfasalazine make me lose any weight?

Will sulfasalazine make me lose any weight?

No.: Only if you had been on steroids and are now off of them. But sfz does not cause weight loss, unless the occasional GI quiziness that some patients get is making you eat less. ...Read more

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Is sulfasalazine an unhealthy drug?

Is sulfasalazine an unhealthy drug?

No.relatively safe!: Sfz is one drug I use the most in patients with many diseases. Aside from an occasional "sulfa rxn", the most common side effect is stomach "queazyness". All individuals taking this drug need to be monitored with blood work at defined intervals (2-3 mo) and they should receive Folic Acid supplements. ...Read more

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Has anyone prescribed sulfasalazine for costochondritis?

Has anyone prescribed sulfasalazine for costochondritis?

No: The use of sulfasalazine would be very unusual for this inflammatory condition. Local heat, anti-inflammatory rx, steroid injection ( with caution), some types of physical therapy are the usual treatments. ...Read more

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Can sulfasalazine cause infertility?

Can sulfasalazine cause infertility?

No: It is extremely rare that a medication will cause infertility. A infection however of the abdomen and pelvic can increase the risk of infertility. ...Read more

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I take sulfasalazine for RA, can I take the tablets that are not EN?

I take sulfasalazine for RA, can I take the tablets that are not EN?

Yes: Sulfasalazine has been used for 70 years to treat rheumatoid arthritis. The enteric formulation - delayed release - was created to help lessen gastrointestinal side effects particularly stomach upset. You should review this with your rheumatologist. ...Read more

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Can u take sulfasalazine and methotrexate together?

Can u take sulfasalazine and methotrexate together?

Methotrexate: Not recommended routinely because combination can increase Methotrexate levels can cause toxicity. ...Read more

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