Doctor insights on:
What Is Scleroderma
Hard skin: Scleroderma literally means "hard skin." it is a connective tissue disease that primarily involves the skin which becomes fibrotic (hardened). Changes also may occur in the blood vessels, muscles, and internal organs. The disease involves autoimmunity whereby the immune system attacks the normal tissues of the body. The cause is unknown. ...Read moreSee 2 more doctor answers
I hate: As a surgeon to get involved but i lost my wife in just two years... It is an autoimmune disease of unknown origin. When just suspected a sedimentation rate, ANA levels, anti scl-70 and anti-centromere antibodies should be stat done. A good resource is this web site: http://www.Synnovation.Com/sclerodermafaq.Html i would seek help from a university based rheumatology department... ...Read moreSee 1 more doctor answer
Scleroderma tests: The diagnosis of scleroderma is based mostly on signs and symptoms. Lab tests may help confirm the diagnosis and even offer some predictions as to risks of certain types of complications. Anti rna-polymerase iii antibody, increases risk of renal crisis and sudden increase in blood pressure, antitopoisomerase ab, increases risk for scaring of the lung, anticentromere ab, pulmonary hypertension. ...Read moreSee 1 more doctor answer
Skin changes: The first sign is usually patchy areas on the skin that often make a linear pattern. Early on, they are slightly pink and thickened, but can be flat and shiny. As time passes, the skin spots enlarge and often become thick and lavender/purple-colored, sometimes with pale flat centers. Scleroderma can also affect the heart, lung, kidney, joints, digestive tract. Please see your doctor if you're worried. ...Read more
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