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Doctor insights on: What Is Saxagliptin

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Is 5 mg saxagliptin equal to 100mg sitagliptin?

Is 5 mg saxagliptin equal to 100mg sitagliptin?

Approximately yes: It may be approximately but no comparitve studies have been done. Sexaglyptine sold under brand name Onglyza (saxagliptin) has staring dose 2.5 mgm and maximum dose 5mgm.And sitaglyptin sold under brand name januvia starting dose is 50 mgm and maximum dose of 100 mgm daily. ...Read more

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How does drug get its name? Why does it sometimes have two names, e.G. Onglyza & saxagliptin?

Trade Name/Clinical: Saxaglipitin is the chemical name which presumably was named by the drug company who created it. Onglyza (saxagliptin) is the brand or trade name saxaglipitin was marketed under. Trade names are chosen for their uniqueness, and drug companies usually undergo extensive public evaluations to determine their acceptance by the public they will be marketed to. ...Read more

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What is the best time to take onglyza (saxagliptin) with breakfast or supper?

Diabetes: Assuming you have type 2 diabetes? I would please ask your endocrinologist who prescribed it, but usually patients take with breakfast because you do not want any dip in your blood sugar at night. Please check with prescribing doctor ...Read more

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I qm takng onglyza (saxagliptin) 5 mg once a day. Is there any problem if i swith to sitagliptin 100 mg once a day?

Should not be: But double check with your doc before switching. Better be safe and know all the details about you. ...Read more

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Can luvox be used with vytoryn and onglyza (saxagliptin)?

Can luvox be used with vytoryn and onglyza (saxagliptin)?

Possibly: Luvox (fluxoxamine, an SSRI) is predominantly metabolized in the liver. it can inhibit (slow down) cytochromes in the liver, which r used 2 metabolize other drugs. This would have the effect of increasing the circulating levels of certain other meds. taking Luvox can increase the blood level of vytorin (ezetimibe and simvastatin) or onglaza. Discuss potential interactions with ur doc & determine the best treatment 4 u :) ...Read more

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Why does onglyza (saxagliptin) have only 2.5mg & 5mg while metformin has 500mg & 1000mg? Why is there big difference in terms of chemical amount?

Why does onglyza (saxagliptin) have only 2.5mg & 5mg while metformin has 500mg & 1000mg? Why is there big difference in terms of chemical amount?

Two different compou: These are two different compounds and belong to different group of medicines, and their effectiveness is based on different dosage.All meds are different compounds and different dosage. ...Read more

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I'm taking onglyza (saxagliptin) 2.5mg and metformin 500mg for a month now. Is this safe? I want to be off these medicines. Will I be cured if taking them?

I'm taking onglyza (saxagliptin) 2.5mg and metformin 500mg for a month now.  Is this safe?  I want to be off  these medicines.  Will I be cured if taking them?

No cures: Metformin, available for almost 50 years is very safe in people with good kidney function. The dpp4s - of which Onglyza (saxagliptin) is one - have been implicated in pancreatitis, and pancreas and thyroid cancers. Talk to your doctor if you are worried. ...Read more

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Is it safe to take onglyza (saxagliptin) while pregnant?

Is it safe to take onglyza (saxagliptin) while pregnant?

Category B: It is considered a category b, which means no risk or adverse fetal effects have been shown but no controlled human first trimester studies are available to confirm. There does not appear to be a risk in the second or third trimester. ...Read more

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Is it safe to take onglyza (saxagliptin) and metformin at the same time?

Is it safe to take onglyza (saxagliptin) and metformin at the same time?

Yes: They are a good combination. There is also a pill that combined both of them together called kombiglyze that is fda-approved for the treatment of type 2 diabetes. ...Read more

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Is it safe to take 5 metformin pills & 5 onglyza (saxagliptin) pills on 1 day and take a break for 5 days while fasting?

Is it safe to take 5 metformin pills & 5 onglyza (saxagliptin) pills on 1 day and take a break for 5 days while fasting?

Absolutely not!: There is no rationale for taking metformin or Onglyza (saxagliptin) in that fashion and taking such large amounts all at once may lead to toxic side-effects. ...Read more

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Recently prescribed cardizem 120 daily-concerned about interactions with vytoryn 10/20..Onglyza (saxagliptin) 5mg and andro gel 1.62 -3 pumps?

Sharing metabolism: Cardizem and Simvastatin do share the area of metabolism in the liver called the cyp450 system. Taking them together cause the prolongation of the effect of one another. ...Read more

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My A1c is 6.5. Is that good enough. I want it to be lower to stop taking medicine. Now I take 1 metformin 500mg 1 day and next day have 2.5 mg onglyza (saxagliptin)?

My A1c is 6.5.  Is that good enough. I want it to be lower to stop taking medicine. Now I take 1 metformin 500mg 1 day and next day have 2.5 mg onglyza (saxagliptin)?

Good control: Your A1c is very good and at goal. At this level, your risk of getting diabetes complications is low. If you want to lower the amount of pills, try to lose weight if you are overweight or obese. Remain active as this makes your Insulin more sensitive. You should be taking metformin and Onglyza (saxagliptin) everyday instead of alternating every other day. ...Read more

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Does onglyza (saxagliptin) cause pan·cre·a·ti·tis if taken for a long time? Is lupus considered as cancer?

Does onglyza (saxagliptin) cause pan·cre·a·ti·tis if taken for a long time? Is lupus considered as cancer?

Side effect and no.: Pancreatitis is a side effect of onglyza (saxagliptin). Usually side effects are unpredictable complications of a drug, not necessarily related to dose or time interval. Lupus is not cancer. It is type of autoimmune disease that can affect pretty much any part of the body, and sometimes can be quite serious, but it is not cancer. ...Read more

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