Doctor insights on:
What Is Polyarthralgia Inflammatory Diseases
Several: A classic is Giant Cell Arteritis, now considered due to Herpes Zoster. Multiple sclerosis is an inflammatory autoimmune disorder. Arteritis and vasculitis associated with lupus in form of lupus cerebritis. Most infections of brain and spinal cord such as encephalitis or meningitis associated with loads of inflammation. ...Read more
Terminology?: There really isn't a specific disease entity we refer to in the U.S. As "chronic inflammatory neurological disorder." however, if you are asking for specific diseases which could be classified as examples of "chronic inflammatory neurological disorders?" those are easier to name such as, cerebral vasculitis, ms, sarcoidosis, lupus cerebritis, and others. ...Read more
I have an autoimmune inflammatory condition, my brother has cmt. Is it unusual to see two uncommon diseases in full siblings or could they be related?
Unusual, yes.: Cmt, charcot-marie-tooth disease is an inherited disease causing peripheral neuropathy. The affected gene is on chromosome 17. The only identified immune genes on 17 code for cell surface proteins involved in intrinsic immunity. There might be a link if you have an autoinflammatory disorder. Consider discussing with a genetic counselor. ...Read more
Autoimmunity.: Genetic predisposition and interaction with pathogens from the environment conspire to cause ibd, which in essence is an autoimmune disorder. Maternal-fetal cell trafficking across the placenta fuels the theory that most if not all autimmune disorders have their origin in fetal (or maternal) stem cells persisting in various organs and stimulating inflammatory response. Stress does not help! ...Read more
Varied: Lupus, rheumatoid arthritis and scleroderma, can cause pericarditis. Kidney failure (uremic pericarditis), tumors, genetic diseases such as familial mediterranean fever, or rarely, medications that suppress the immune system can also be the cause. In a number of cases of pericarditis, the cause is unknown. This is referred to as idiopathic pericarditis. ...Read moreSee 1 more doctor answer
IBD defined: Earlier healthtap answers may help. Briefly ibd is a spectum of inflammatory diseases of GI tract. At one end of the spectrum is ulcerative colitis---a disease confined to the mucosal surface of colon. At the opposite end of the spectrum is crohn's disease--a transmural (full thickness) inflammation of any part of GI tract (from mouth to anus). Both are systemic & increase colon cancer risk. ...Read moreSee 1 more doctor answer
Cure for IBD?: Ulcerative colitis involves inflammation of the colonic mucosal surface, so colectomy (removal of the colon) is curative for it. Crohn's disease however is a transmural (full-thickness) inflammation of any part of the GI tract (from mouth to anus). Crohn's is not curable, but it is controllable with medications (see my previous healthtap answer regarding "step up" versus "top down" treatments. ...Read moreSee 1 more doctor answer
Many options: 1. 5-asa medications (sulfasalazine, asacol, (mesalamine) pentasa) may work for mild ulcerative colitis (uc), but not crohn's disease. 2. Steroids work, but are only useful for short course because of side effects. 3. Azathioprine (imuran), 6-mp, Methotrexate are often effective, and reduce the need for steroids. 4. Remicade, Humira are often effective for crohn's, sometimes for uc. 5. Surgery if needed. ...Read moreSee 1 more doctor answer
No short answer here: That's a really complicated question. There are a whole host of disorders that cause fibrosis of the lung. The most common is called uip, which is a disease of unknown etiology, that is not related to smoking or other disorders, and results in scarring of the lungs i would recommend a pathology text book to see a list of all the possible lung disorders. ...Read more
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