Doctor insights on:
What Is Plasma
Solutes in plasma: Plasma osmolarity is a reflection of various salts in plasma. It can be measured directly, usually by freezing point depression, or commonly calculated using the following equation = 2[na+] + [glucose]/18 + [ BUN ]/2.8 where [glucose] and [bun] are measured in mg/dl. Normal value is 270-310 milli-osmoles per kilogram. ...Read more
Pituitary hormone: Hi. ACTH is a hormone from the pituitary gland that travels by the bloodstream to the adrenal glands and stimulates cortisol production (and to a lesser extent, aldosterone). The cortisol feeds back to the pituitary to regulate ACTH release (also effects on hypothalamic CRH, but we'll keep it simple). ACTH positive feedforward & cortisol negative feedback works beautifully. Diseases can affect it. ...Read more
Conc. electrolytes.: These refer to the concentration of electrolytes in the body/plasma, or the electrolyte-water balance. These measure the same thing, only that osmolality is the number of osmoles per kilogram of solvent or osm/kg, while osmolarity is the number of osmoles per liter of solution or osm/ltr. Osmolality excludes the solute, while osmolarity includes it, so osmolality has a slightly higher reading. ...Read moreSee 1 more doctor answer
High albumin: Have your Albumin rechecked. Dehydration can affect Albumin level by increasing it. Other causes could be tuberculosis, hepatitis and hiv. It can also be seen in congestive heart failure, glucocorticoid excess and congenital disorders. Speak to the physician who ordered the test for more information if you are the patient. ...Read more
ACTH: Good question but hard to answer in a short paragraph. Please go online and look up ACTH in articles designed for patients not doctors. That should be of great help. Any questions - send them to me. ...Read more
Pituitary hormone: Acth comes from the pituitary and regulates adrenal cortisol. It is measured in an immunoassay. Acth is a small peptide, broken down quickly in plasma, and is tricky to assay; results can be unreliable if the sample is not processed properly. It is measured in the work up of adrenal and/or pituitary disorders, such as cushing's disease or pituitary deficiency. ...Read more
Proteins, etc: Plasma is a yellowish liquid portion of whole blood after red blood cells, white blood cells and platelet are removed by centrifuge. It contains many proteins, hormones, and electrolytes essential for our life. For proteins, it includes immunoglobulin (for immunity), clotting factors (for hemostasis reducing bleeding), lipoproteins (carry lipid), enzymes and hormones, etc. ...Read more
Test adrenal fxn.: This test is to check on whether or not your adrenal glands are working right. The acth action is to increase production and release of corticosteroids. In the test, a small amount of synthetic acth is injected and the amount of cortisol the adrenals produce in response is measured. This is used to check for things like primary and secondary adrenal insufficiency, and addison's disease. ...Read more
Liquid in blood: Plasma refers to the liquid portion of blood as opposed to the cells which account for about 45%. It's straw colored and contains protein, immune globulins and clotting factors. If you donate plasma you regenerate it fairly fast and can donate frequently. Thanks for trusting HealthTap! ...Read more
Not recommended: Red Cross and many facilities in US will not accept products from pay-for-donate locations. This is due to the concern that a potential donor might not be totally honest in the history questions if seeking $$ and this could contaminate the blood supply. Volunteer donors have no motivation to not provide direct answers. ...Read more
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