Doctor insights on:
What Is Monoclonal Paraproteinemia
Excess of Plasma cel: Plasma cells in our bone marrow make antibodies. Sometimes they become overly active/reactive and produce abnormal proteins called paraproteins. Most such protein production is benign and not uncommon in older folks. Sometimes it is excessive(more than 1gram/day) then we get concerned about a condition called multiple myeloma (paraproteins over 3 grams). ...Read more
See below: Increased immunoglobulin ( antibody) level in small amounts from single clone of plama cells ( present in bone marrow) in small amounts without causing any symptoms unlike in multiple myeloma. ...Read moreSee 1 more doctor answer
MGUS: Is a common precancerous condition affecting people 50 years of age and older. It was first described by mayo clinic researchers in 1978 and is characterized by the presence of an abnormal protein in the blood called a (monoclonal) protein or m protein.Mgus has a small risk (1 percent each year) of progressing to a blood cancer called multiple myeloma or a related condition. ...Read more
Mayo Clinic say: Plasma cells are a type of white blood cell. They are found in your bone marrow. Plasma cells produce some of the antibodies that help your body fight infection. Monoclonal gammopathy of undetermined significance occurs when plasma cells in your bone marrow produce an abnormal protein called monoclonal protein (m protein). ...Read more
Blood & urine tests: Mgus is the presence of an abnormal protrein in the blood made by a type of white blood cell called a plasmacyte. In most cases, it is at a low level and is something that just has to be followed. However, it can be the precursor of the disease called multiple myeloma and as such a hematologist or medical oncologist will order tests to rule this out which may include blood, urine and simple x-rays. ...Read moreSee 1 more doctor answer
No: Ebv infection, the cause of mononucleosis is not usually related to monoclonal gammopathy. Ebv induced lymphoma may produce monoclonal gammopathy, but that would be an uncommon situation. ...Read more
Not realy: It's estimated that between 10 and 25 percent of people with monoclonal gammopathy of undetermined significance develop a more serious condition, such as multiple myeloma or other cancers or blood disorders. Other complications include fractures and blood clots. ...Read more
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