Doctor insights on:
What Is Lynphoma
Lymphoma: There are many types of lymphoma-from the agressive ones to the indolent ones. Each type has different biology and different response to therapy, as well as different prognosis etc. However, in general, lymphoma is a chemosensitive disease and is a radiosensitive disease. Yes, some lymphoma can be cured. ...Read more
T cell lymphoma?: I think you mean t cell lymphoma, a cancer of t cells or thymocytes that can cause lymph gland enlargement, low blood counts, fevers, and sweats. A particular subtype is gamma-delta (the greek letter for d) hepatosplenic lymphoma, which could also be what you're referring to. A good source of information is the leukemia & lymphoma society of america's website. ...Read more
Symptoms and imaging:
People usually present with symptoms -- eg, fever, chills, night sweats, fatigue, lymph node enlargement, spleen enlargement, etc.
Then (or sometimes incidentally) abnormal lymph nodes are noted on ct scans.
A biopsy (of lymph nodes and/or bone marrow) is needed for diagnosis.
Less often blood abnormalities show a leukemic (blood) component of lymphoma or other abnormalities. ...Read more
Lymphoma itself is not communicable/infectious.
However, some infectious diseases may be associated with the development of various types of lymphoma. Eg -- gastric malt (hp0, ocular (chlamydia psittaci), spelnnic (hcv), t cell (htlv1), nhl (hiv), primary effusion (hhv8), ipsid (campylobacter jejuni), primary cutaneous bcl (borrelia burgdorferi). ...Read more
B symptoms: Symptoms can include fever, night-sweats and weight loss for both non-hodgkin's lymphoma and hodgkin's disease. These are referred to as b symptoms and they are used in the staging of lymphoma. Thus a stage iii lymphoma with b symptoms would be given a stage iiib status. Other symptoms are related to pressure from the tumor causing pain, or fatigue. ...Read more
See below...: The diagnosis and treatment of lymphoma, like any other cancer, should be managed by an oncologist. Many signs and symptoms are possible at presentation including unexplained weight loss, lymph node enlargement, lack of appetite, night sweats, fatigue, prolonged fever, enlarged spleen and/or liver, etc. ...Read more
Lymphoma cells continue to divide and grow more than they die. Two things happen
1) their increasing size affects normal organ function or physically pushes on organs which impair their function or
2) they produce substances that are toxic or debilitate the patient
both these things eventually weaken the patient, prevent the production of normal blood cells and can lead poor immunity & infection. ...Read more
Lymphoma...: Often, the first sign of lymphoma is a painless swelling in the neck, under an arm, or in the groin. Lymph nodes or tissues elsewhere in the body may also swell. The spleen, for example, often becomes enlarged in lymphoma. Symptoms of lymphoma may include the following: fevers, chills, unexplained weight loss, night sweats, fatigue, and itching. ...Read more
Cancer. Net info:
Depends on type, stage, patient characteristics. There is no one answer. More information is needed.
A comprehensive and trusted overview of non-hodgkin lymphoma (nhl) is here: http://www.Cancer.Net/cancer-types/lymphoma-non-hodgkin treatment info: http://www. Cancer. Net/cancer-types/lymphoma-non-hodgkin/treatment. ...Read more
Like other cancers..: lymphoma arises from an unlucky combination of genetic mutations in lymphoid cells during our lifetime. Risk factors include exposure to toxins, family history, or a severe immune suppression (e.g. HIV). Most often, the proximal cause can not be determined, and is mostly just bad luck, since our body is naturally subjected to millions of genetic mutations over our lifetime. ...Read more
Many variables: Survival and treatment selection depend on many variables: stage of disease, type of lymphoma, age of patient, associated symptoms, overall performance status, specific pathologic and blood based risk factors, as well as response to therapy. It is too broad to cover all aspects specifically so I would refer you to online resources such as acs. Org or institutional web resources like mdacc or mskcc. ...Read more
Normal nodes can be: Found from head to toe, and lymphoma can arise in any place where nodes are, and even "extranodal" sites. Fever, weight loss, and drenching sweats are called b symptoms, indicating a wore prognosis, pruritus or itching is another finding. There is the hodgkin's type, and a variety of others. This is very treatable and curable. ...Read more
Depends what type: There are about 60 types of lymphomas, some very indolent with survival same as normal people, and many with moderate prognosis, with survival measured in 5 to 10 years. Rare few are quite aggressive with survival measured in months or weeks. Best know exactly what kind and the diagnosis by expert will predict probability of survival. Talk to your doc. Lymphoma is a misnomer, it is not one disease ...Read more
Could be several: Lymphoma is a general category which includes many subtypes of hodgkins and non-hodgkins lymphomas. They may manifest slowly over years while higher grades progress more quickly. As a class, lymphomas my occur practically anywhere, so the possible symptoms can vary substantially. ...Read more
It depends on urheal: Your health and symptoms can be indicators of the nature of an ilness. You may not be able to predict it but if you are unwell, your doctor would investigate the cause. The symptoms suggestive of lymphoma will include general ill health associated with fevers and enlarged lymph nodes in any of your body areas. Ultimately a biopsy of a mass or an enlarged node will be required to confirm this diag. ...Read more
Yes, it is possible: There are different types of lymphomas which can range from slow growing to rapidly progressive. All lymphomas, even low grade can lead to death if not treated. ...Read more
Why do you ask?: People who just feel unwell, perhaps because their life circumstances are difficult, often focus on lymphoma because they know it's subtle in its presentation. Ask yourself whether this might be you. If you have no mass, no fever, no obvious weight loss, and no night sweats, your real odds of lymphoma are very small. And there is no harm in a delay in the daignosis, unlike other acncers. ...Read more
Not enough space...: Lymphoma cannot be really discussed in the space available here; however, generally speaking, lymphoma is a form of cancer that usually occurs in lymph nodes but also in other organs containing lymphoid tissue like spleen, liver, gastrointestinal tract, etc. Multiple subtypes exist and they have variable clinical evolution from slow evolving cases to very aggressive ones. ...Read more
Combination modes: Masses, enlargement of lymph nodes along the chains in neck, axilla, inguinal etc are the common signs but rare ones include masses outside nodes like stomach or skin. Imaging can detect enlarged nodes internally. If your doctor suspects, definitive diagnosis requires biopsy, plus ancillary tests that includes flow cytometry molec genetics immunostains to classify which type among the 60 kinds ...Read more
Are based on their microscopic appearance, expression of proteins on the cell surface, or specific gene mutations.
To name a few: Hodgkins Lymphoma (classical, Lymphocyte rich, etc.). B-cell non-Hodgkins (NHL) include: Lymphoblastic, Burkitt's, Diffuse Large B-cell, Follicular, Mantle Cell, Small Lymphocytic. T-cell lymphomas are yet another group: Anaplastic Large Cell, Angioimmunoblastic, etc. ...Read more
They grow...: And they subside. Sometimes with no treatment. Relatively benign teatment now encourages some to offer retuxan based therapy. Focal radiotherapy has also been used. Growth rate is variable and usually survival +/- therapy is quite long.. ...Read more
Large lymph nodes: That is the most common symptoms. But it may also include weight loss, fever, drenching sweats, abnormal blood counts, autoimmune problems and compression of organs resulting from the enlarged lymph nodes leading to pain, jaundice, bone fractures or neurological complications. ...Read more