Doctor insights on:
What Is Low Risk For Down Syndrome
Incidence increases : The incidence of down syndrome actually begin to increase after the mid twenties and cross the 1/100 risk from 40-44 & 1/50 at 45+. Risk of an unexpected outcome is a steady 4% for any pregnancy + any added issues. Where & how you can find a spouse or surrogate to carry an heir is a a different issue. Hopefully this info helps. ...Read more
Is amniocentesis a safe enough procedure to be performed even when risk of Down syndrome per marker tests is low ?
Bradycardia: While children with downes syndrome may have a slow heart rate, there are many other causes of slow heart rate, such as hypothyroidism and others. Down's syndrome is best characterized by the constellation of associated characteristics and chromosomal abnormality. ...Read moreSee 1 more doctor answer
Child with Down syndrome has epicathal folds, thick tongue and low set ears. What else could be wrong?
Which is a better predictor of Down syndrome during the first trimester screening, low papp-a or high hCG levels? Or the ratio between the two values?
5w4d pregnant Hcg at 14031 (up from 5859 in 48h). Are these normal values or is there risk for Down syndrome?
My NT scan came out good but my blood work came back high risk for down syndrome(1:155) what are my chances for a healthy baby?
High risk Downs: That means that you have a 1 in 155 chance of having a baby with down's syndrome. Keep in mind, you are young, and downs is more common in women of advanced maternal age. Speaking to the doctor that ordered the test is also very important. ...Read more
What to do if I am 30 years old, my AFP screening read 1 out 74 risk for down syndrome. What to do if I am scared!?
Time for consultatn: You could consult with a geneticist to see what your real risks are before doing anything. An estimated 4% of pregnancies end up with unexpected results, cleft lip, premi, sick, defects and your study adds another 1.5%. A review of both parents family tree may reveal more issues.You may just want answers to keep from unraveling and a chromosome study (amnio) can confirm or exclude it. ...Read more
Ab 9 weeks pregnant. My cycles were 45 days long and I got pregnant from ovulating on day 30. Does late ovulation increase risk for Down syndrome?
Downs syndome: Fertilization of an aged egg may predispose to Down's Syndrome ...Read more
Chromosome defect: Ds is one of the more common chromosome(c) defects that can survive pregnancy (many others miscarry).Eggs are supposed to have a single 21c & combine with the 21 from dads normal sperm.Here a pair of moms 21c +dad's 21 creates a baby with the extra 21c in all tissues.This extra material confuses the creation of body parts causing ds..Various prenatal tests can pick up signs early on. ...Read more
DNA defects: Chromosome 21 seems to be the cause. Two most common types are trisomy 21 where ther is an entire extra chromosome in each cell. The other is translocation where only an extra piece of the chromosome is found. It can be an isolated defect or an inherited defect. Rare exotic forms include polyploidy and haploid forms and chimeras. Sorry you asked? ...Read moreSee 1 more doctor answer
Chromosome defect: Ds is one of the more common chromosome(c) defects that can survive pregnancy (many others miscarry).Eggs are supposed to have a single 21c & combine with the 21 from dads normal sperm.In ds the pair of moms 21c +dad's 21 creates a baby with the three 21c in all tissues.This extra material confuses the creation of body parts causing ds..Various prenatal tests can pick up signs early on. ...Read more
Supportive care: Down syndrome has a well recognized pattern of obvious features and several common vulnerabilities. An evaluation for treatable heart defects and other problems helps assure the patient with best chance at a good life. Supportive care for their academic and growth challenges is also required.With modern health care, these patients can live well into their 60's in a protected environment. ...Read more
Mistake in chromosom: During the formation of normal eggs or sperm the chromosome(c) pairs are supposed to split leaving one of each in the egg/sperm.At conception the joining of egg/sperm brings together the pair & as tissue grows it has the proper number in each cell. With ds the egg has a pair of 21c and at conception a triple 21 is created. All cells derived after will have an extra 21 & become a ds child. ...Read more
Rarely: Downs syndrome is usually related to a trisomy defect that develops during the initial cleavage of the cells during primary fetal development. A form can occur as a translocation that may be carried by a parent. An assumption is that the 21 chromosome may be damaged by maternal age or by some environmental factor that then results in downs syndrome. Most cases are just by chance. ...Read moreSee 1 more doctor answer
Depends on parents: An unaffected mother or father could have a balanced(normal) set of chromasome material where a piece of one 21 chromasome is stuck on another.If the egg or sperm had the normal 21 and an extra 21piece hidden on another chromasome, they could pass it to the baby. It only takes an extra piece of 21 to cause ds.It is important to study ds to verify type, as translocation ds can recur each pregnany. ...Read moreSee 2 more doctor answers
No autosomal: Down syndrome happens when an extra 21 chromosome is present in all the cells of the body. It happens before conception when the donor egg fails to shed one of its 21 chromosomes in the formation of the egg & the male 21 joins the female pair & creates an embryo with 3 number 21's. It has nothing to do with traits or mutations in the gene code. ...Read moreSee 1 more doctor answer
- Talk to a doctor online
- What is the risk of having a down syndrome baby?
- Down syndrome risk calculator
- Risk of down syndrome
- Risk of having baby with down syndrome
- Risk of having a down syndrome baby
- Risk of having a baby with down syndrome
- Risks of down's syndrome in pregnancy
- Morning sickness risk down syndrome
- High risk of down syndrome