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What Is Glutamate Rebound
Glutamate "rebound": As the name implies, glutamate receptors blocked during ingestion of alcohol (or ketamine) are reactivated ("rebound") after the effects of both are diminished, and high levels of glutamate are then felt with the perceptions of post alcohol withdrawal ("hangover") similar to when one eats foods containing high mono sodium glutamate, a preservative contained in many foods. ...Read more
Neuron junctions.: Synapses are junctions between neurons, or nerve cells. Nerves transmit signals throughout the body, & synapses are gates where chemical signals are transduced to electrical ones. Synapses may be simply described as excitatory or inhibitory, and often depends on the neurotransmitter involved. For example, excitation of the heart and inhibition of the gut are part of the fight or flight response. ...Read more
MSG: Msg is a flavoring agent and Amino Acid commonly used in asian cooking. It imparts a meaty taste to food. It is not toxic but in some causes a feeling of dizziness and even nausea. The effects, if they occur are not serious or dangerous but most foods with msg are labeled so they can be avoided and asian restaurants will frequently list foods as msg free. ...Read more
Not known so...: Msg has not been shown to cause or adversely affect hypertension. It is a rather common food additve/sweetener and fortunately relatively safe, in moderation of course. If you have problem with hypertension, obviously you should consult doc for eval and treatment. It is not necessary that you advoid msg, but too much of anything is not good. Consult your doc.Good luck. ...Read more
Important.: Dopamine is a neurotransmitter, in other words it is the messenger that carries the message in a dopaminergic system that serves multiple functions. one of these functions has to do with impulse control movement disorders in tick disorders and Tourette syndrome. treatment usually involves dopamine blockers which exert some regulation on the Dopminergic system connected to this problem ...Read more
Not really: The basic problem that we have in understanding mood disorders is that we seem to be "stuck" with the idea that bipolar disorders have to have two primary states. But, as you point out, manic dysphoria (energized but unpleasant moods) doesn't reallly fit this model. I guess the closest answer would be calm or lethargic euphoria. Since that has low mental energy and happy feelings. ...Read more
I know that GABA inhibits release of dopamine, but what does glutamate do for dopamine? Precisely what would inhibition of NMDA do to dopamine?
What is the best medication for depersonalization disorder? Is low testosterone causing my anxiety symptoms?
Depersonalization: Depersonalization can come from multiple sources. For depersonalization disorder, medications are not the main part of treatment -- psychotherapy is. The medications may support the person and help manage overwhelming anxiety and depression, etc. They will not cure the condition, though. Such a person may be dealing with a history of severe abuse, and depersonalization has become a coping style. ...Read more
Does anger elevates epinephrine? What is the best medication to treat people with high epinephrine . I heard that propranolol is good, is that right?
Interesting question: In the "fight or flight" scenario, there is a definite increase. However, having a "high epinephrine" level is difficult to understand. There are instances where certain tumors produce excess of this chemical. Your question about Propranolol is easier to answer. This agent is called a beta "blocker" it does not reduce the amount of Epinephrine but blocks its effects ...Read more
If ritalin depletes dopamine and wellbutrin (bupropion) makes dopamine, what is the point of taking both?
Ritalin (methylphenidate): Ritalin (methylphenidate) does not deplete Dopamine per se. It does "streamline" the production of noradrenaline by regulating the reuptake of Dopamine at the synaptic junction, therefore allowing more Dopamine and noradrenaline exposure to the neuron, which is stimulated. Wellbutrin (bupropion) (buproprion) does the same for serotonin and dopamine, therefore potentiating the effect of both. ...Read more
I heard that taking magnesium aspartate is less beneficial for treating depression due to the excitatory effects of aspartate. Is this true?
Vimpat (lacosamide): It is Schedule 5 controlled substance (less potential for abuse than the higher schedules 1-4). ...Read more
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