Doctor insights on:
What Is Cushing's Syndrome
Symptom / sign mix: The familiar physical changes from excess glucocorticoids from any cause, made in the body or prescribged. Red, swollen face, hypertension, glucose intolerance, truncal obesity, fat pad on back of neck, fragile skin, likelihood to get infections, mood problems, acne, more. Contrast "cushing's disease" in which these by definition result from a pituitary adenoma making acth. ...Read more
Hormonal...: It is hormonal problem where the body experiences changes due to too much glucocorticoids which might be elevated for different reasons like for example adrenal tumors( usually benign), medications, other hormonal issues. Symptoms can be weight gain, elevated blood sugar, fatigue, muscle weakness, moon face, among others. ...Read more
My lover has just been diagnosed with cushing’s syndrome. I am worried but she acts like it is not a problem. Who can tell me what it means?
Too much cortisol: Cushing's syndrome means the body has too much cortisol in it. This can lead to high blood pressure, diabetes, osteoporosis. It can be caused by medications like Prednisone (most common cause - doesn't need treatment, but should try to minimize steroid dose), or by a cortisol producing tumor (needs surgery) or a certain type of pituitary tumor (called cushing's disease - also needs surgery). ...Read moreSee 1 more doctor answer
No, it's a tough one: Cushing's syndrome is a condition where your body makes too much cortisol (a hormone). A blood draw, 24 hour urine measurement of cortisol, midnight salivary cortisol measurement or a test called dexamathasone suppression test can be done to give you the diagnosis. Often time, you'll need multiple or all of the tests above to make an accurate diagnosis. It's one of the hardest diagnosis to make. ...Read moreSee 1 more doctor answer
Cushings varies: The symptoms of Cushing's disease vary, but they can include weight gain, increased blood pressure, a round-shaped face, headaches, mood changes, altered menses, hair growth, the formation of a lump at the top of the back, and fatigue / tiredness. ...Read moreSee 1 more doctor answer
Many: The signs and symptoms of cushing's syndrome vary. Common signs and symptoms involve progressive obesity and skin changes, such as: weight gain and fatty tissue deposits, particularly around the midsection and upper back, in the face (moon face) and between the shoulders (buffalo hump) pink or purple stretch marks (striae) on the skin of the abdomen, thighs, breasts and arms thinnin. ...Read more
Cushing's syndrome: Cushing's syndrome is a condition where your body makes too much cortisol (a hormone). A blood draw, 24 hour urine measurement of cortisol, midnight salivary cortisol measurement or a test called dexamathasone suppression test can be done to give you the diagnosis. Often time, you need multiple or all of the tests above to make an accurate diagnosis. ...Read moreSee 1 more doctor answer
Many symptoms: Symptoms / signs: truncal obesity (mr. Potatohead look), "moon" facies, thinning of skin, easy bruising, "buffalo" hump in upper back, purple stretch marks, hypertension, fatigue, psychiatric sx, insomnia, excess hair growth, muscle weakness and loss. Symptoms are often progressive and should prompt screening. ...Read more
Many: Facial plethora, acne, hypertension, weight gain, swelling, violaceous streaks, easy bruising, proximal muscle weakness, diabetes, central fat accumulation, elevated cholesterol, osteoporosis - all are manifestations of cushing's syndrome. The severity of symptoms and signs will reflect the duration and severity of steroid excess. ...Read more
Many features: Cushing's is a rare condition, but important to recognize since it can often be cured. There is abdominal (central) obesity (buffalo hump) often with diabetes and hypertension, but also thin skin (bruising, purple striae), rapid change in appearance, muscle weakness, maybe hirsutism, cognitive difficulties. See your doctor. ...Read more
Cushing's unknow 10y: Yes Cushing's can be a slow developing problem. The only way to know is to be tested for it. I always recommend a 24 hr urine for urinary free cortisol AND and overnight Dexamethasone suppression testing. It can be a difficult Dx to make early in the evolution of Cushing's. Would be happy to get more details with a second opinion. ...Read moreSee 1 more doctor answer
Endocrinology: Cushing's is an endocrine disorder so seeing an endocrinologist is the best way to get the diagnosis. ...Read more
Did anyone been diagnosed with cushing's syndrome but there tests didn't show it the first time or what?
Cushing's diagnosis: The diagnosis of cushing's can be subtle and complicated. The presence of a nodule or a tumor does not establish the diagnosis. The biochemical tests (blood, urine) can be difficult to interpret, since we all make cortisol. If there is a question, make sure you are seeing an endocrinologist. ...Read more
Is it possible to be diagnosed with cushing's syndrome but there tests didn't show it the first time or what?
Difficult diagnosis: Hi. Yes, Cushing's can be one of the more difficult and subtle diagnoses in all of endocrinology because of fluctuations in adrenal function throughout the 24-hour period. I see you're in my town. I probably know who diagnosed you, if it's an endocrinologist! Proceed with the work up. Assuming the diagnosis is correct, you don't want to leave it untreated. Good luck! ...Read more
Can one have cushing's syndrome for the past 10years and not know about it? Would the symptoms be mild/slowly progressing all the while?
Cushing's: Sometimes Cushing's comes on fast, but sometimes it can be present for years before it is diagnosed. The symptoms of Cushings, central obesity, diabetes, hypertension, are very common. Raising suspicion for Cushings is abdominal striae, bruising, hirsutism, low potassium, rapid onset, and others. The screening tests for Cushings are fairly easy to do. ...Read moreSee 1 more doctor answer
Many options: First, find out what's causing the cushing's syndrome. If it's due to overuse of steroids, cut down on the dose. If it's due to a tumor, surgery is the best treatment.Tumor in the pituitary can be removed by neurosurgeons, tumors in the adrenal, pancreas, lung can be removed by surgeons. Radiation therapy is used if surgery is not complete. Last but not least, medications can be used. ...Read moreSee 1 more doctor answer
Depends: The treatment options depend on the cause of the cushing's syndrome. If the cause is due to overuse of steroids, then the treatment is to lower the dose. This is the best case scenario. Other treatment options involve: surgery (pros: cure possible, cons: surgery +/- complications), radiation therapy (cons: side effects), medications (cons: usually not a cure, side effects from med)... ...Read moreSee 1 more doctor answer
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