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Doctor insights on: What Is Cushing Disease

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What is cushing's disease?

What is cushing's disease?

Pituitary tumor: Cushing's syndrome is any conditions that cause the adrenal gland to produce too much cortisol. Cushing's disease is a adenoma (tumor) in the pituitary that produces a hormone called acth which causes the adrenal gland to produce too much cortisol. ...Read more

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Dr. Barbara Lavi
51 doctors shared insights

Cushing Disease (Definition)

Cushing disease is excessive cortisol production due to an acth secreting pituitary adenoma. Acth stimulates the adrenals to produce excessive cortisol, leading to central obesity, lack of growth in children, high blood pressure, hyperglycemia, muscle weakness and skin fragility. It can also ...Read more


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What is ?Cushing's disease?

What is ?Cushing's disease?

Pituitary ACTH: Cushings syndrome is a clinical syndrome produced by excess cortisol in the body. Cushings disease is one of the potential causes of the syndrome in which a benign pituitary tumor secretes an excess of acth (adrenocorticotropic hormone) this stimulates adrenal secretion of excess cortisol and produces cushings syndrome. ...Read more

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What is addison's disease?

What is addison's disease?

Adrneal failure: Rare but very serious, and often missed for a long time especially if the person is considered to suffer emotional illness. The adrenal cortex fails to make the cortisol that one needs to stay perky; nausea and weight loss are only the beginning. President kennedy suffered from it. Patients need to carry a medical alert and a cortisol needle. ...Read more

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What exactly is Cushing's disease?

What exactly is Cushing's disease?

Pituitary tumor: Cushing's syndrome is any conditions that cause the adrenal gland to produce too much cortisol. Cushing's disease is a adenoma (tumor) in the pituitary that produces a hormone called acth which causes the adrenal gland to produce too much cortisol. ...Read more

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What is cushing disease ?

What is cushing disease ?

Disease vrs Syndrome: Cushing disease, which is hypercortisolism caused by an acth-secreting pituitary adenoma, is the most common cause of cushing syndrome, and is responsible for 60% to 70% of cases. Cushing syndrome is mainly caused by other sources of corticosteroids like the medicines dr prescribe to treat many conditions ( prednisone, medrol, (methylprednisolone) solumedrol, (methylprednisolone) deposed rol, etc) commonly in copd, asthma, allergies. ...Read more

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What exactly is addison disease?

Adrenal insufficienc: Addison's disease is adrenal insufficiency, or lack of adrenal hormones, which can be an acute emergency, but is treatable with cortisone and other medication. It results from the destruction or surgical removal of the adrenal glands (you have two) and was more common when it used to be caused by tuberculosis years ago. ...Read more

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What exactly is addison's disease?

Adrenal failure: Destruction or dysfunction of the adrenal cortex (from a variety of causes) leading to inadequate cortisol production. May be life-threatening as cortisol release is a critical part of the body's response to infection, inflammation and other stresses. ...Read more

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In what way is cushings disease diagnosed?

Overnight: Do an overnight Dexamethasone suppression test: draw serum cortisol in the morning. Then take 1 mg of Dexamethasone at bedtime and repeat the serum cortisol the next morning. Failure to suppress is indicative of cushing's disease. ...Read more

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What is graves disease?

What is graves disease?

Over active thyroid: Graves' disease is an autoimmune disorder, meaning it is caused by antibodies against the thyroid. These antibodies "trick" the thyroid into making more thyroid hormone than it is supposed to. That leads to symptoms such as excess sweating, palpitations, tremors, frequent bowel movements and weight loss. ...Read more

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What is Cushing syndrome?

What is Cushing syndrome?

Cushing syndrome: read this: http://en.wikipedia.org/wiki/Cushing%27s_syndrome

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What is hashimoto's disease?

What is hashimoto's disease?

Autoimmune thyroid : Autoimmune thyroid disease can cause hypothyroidism. The body produces antibodies to thyroid hormones. Some theorize that gluten sensitivity or heavy metal toxicity can trigger it. ...Read more

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What is the Willis-Ekbom disease disease?

What is the Willis-Ekbom disease disease?

Restless Legs: Restless Legs Syndrome (RLS), also known as Willis-Ekbom Disease, is a neurological condition associated with abnormal sensations in the legs. It is estimated that 5% of the general population and as many as 10% of those over the age of 65 have this disorder. http://www.hopkinsmedicine.org/neurology_neurosurgery/centers_clinics/restless-legs-syndrome/what-is-rls/ ...Read more

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What sort of disorder is cushing disease?

Cushing's disease: Cushing's disease is a condition where the pituitary (tumor) is producing too much acth (adrenalcorticotropic hormone). This hormone stimulates your adrenal glands to produce extra cortisol (stress hormone) which in excess can cause a lot of metabolic problems. ...Read more

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Hi. What is wilson disease diseas?

Hi. What is wilson disease diseas?

Copper: Wilson's disease is a disorder of copper metabolism causing too much copper in the blood and tissues. ...Read more

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What is hashimotos disease?

What is hashimotos disease?

Hashimoto's disease: Hashimoto's disease is an autoimmune condition in which your body makes antibiodies against your thyroid gland. This often produces inflammation, sometimes tenderness, and an overactive gland initially, but eventually the chronic inflammation leads to thyroid failure and the need to take thyroid hormone. ...Read more

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What is celiac disease.?

What is celiac disease.?

Celiac disease: Celiac disease is atrophy of the intestinal villi caused by an immune response to gluten and gliadin. ...Read more

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What is celiac disease?

What is celiac disease?

Celiac Disease: Celiac disease (gluten-sensitive enteropathy) has three of the following features: villous atrophy; malabsorption, weight loss, or other signs of nutrient or vitamin deficiency; and resolution of the mucosal lesions and symptoms after withdrawal of gluten-containing foods (usually within a few weeks to months). Diarrhea, weight loss, and antibodies against gliadin ...Read more

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What is cushing's syndrome?

Symptom / sign mix: The familiar physical changes from excess glucocorticoids from any cause, made in the body or prescribged. Red, swollen face, hypertension, glucose intolerance, truncal obesity, fat pad on back of neck, fragile skin, likelihood to get infections, mood problems, acne, more. Contrast "cushing's disease" in which these by definition result from a pituitary adenoma making acth. ...Read more

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What is crohn disease?

What is crohn disease?

Inflammatory bowel: Crohn's disease is an inflammatory bowel disease, presumably run in families, more in caucasians, which can affect the whole GI from mouth to anus. It is a skipping inflammation, unclear cause, causing problem with absorption and secretory function and causes cramping, and diarrhea and the destruction of the intestinal lining results in fistula formations. ...Read more

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What is thyroid disease?

What is thyroid disease?

Many types.: Thyroid disease is a nonspecific term which indicates there is an abnormality of thyroid function. These include excess secretion of thyroid hormones, decreased secretion, nodules including cancer, and inflammation. A variety of tests help determine the specific type of disease. ...Read more

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What is cushing disease ?

Disease vrs Syndrome: Cushing disease, which is hypercortisolism caused by an acth-secreting pituitary adenoma, is the most common cause of cushing syndrome, and is responsible for 60% to 70% of cases. Cushing syndrome is mainly caused by other sources of corticosteroids like the medicines dr prescribe to treat many conditions ( prednisone, medrol, (methylprednisolone) solumedrol, (methylprednisolone) deposed rol, etc) commonly in copd, asthma, allergies. ...Read more

See 1 more doctor answer
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What is cushing's disease?

Pituitary tumor: Cushing's syndrome is any conditions that cause the adrenal gland to produce too much cortisol. Cushing's disease is a adenoma (tumor) in the pituitary that produces a hormone called acth which causes the adrenal gland to produce too much cortisol. ...Read more

See 1 more doctor answer
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What is ?Cushing's disease?

Pituitary ACTH: Cushings syndrome is a clinical syndrome produced by excess cortisol in the body. Cushings disease is one of the potential causes of the syndrome in which a benign pituitary tumor secretes an excess of acth (adrenocorticotropic hormone) this stimulates adrenal secretion of excess cortisol and produces cushings syndrome. ...Read more

See 1 more doctor answer
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What sort of disorder is cushing disease?

Cushing's disease: Cushing's disease is a condition where the pituitary (tumor) is producing too much acth (adrenalcorticotropic hormone). This hormone stimulates your adrenal glands to produce extra cortisol (stress hormone) which in excess can cause a lot of metabolic problems. ...Read more

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What are the symptoms of cushing disease?

What are the symptoms of cushing disease?

Many symptoms: Symptoms / signs: truncal obesity (mr. Potatohead look), "moon" facies, thinning of skin, easy bruising, "buffalo" hump in upper back, purple stretch marks, hypertension, fatigue, psychiatric sx, insomnia, excess hair growth, muscle weakness and loss. Symptoms are often progressive and should prompt screening. ...Read more

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What exactly is Cushing's disease?

Pituitary tumor: Cushing's syndrome is any conditions that cause the adrenal gland to produce too much cortisol. Cushing's disease is a adenoma (tumor) in the pituitary that produces a hormone called acth which causes the adrenal gland to produce too much cortisol. ...Read more

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What can I use for cushing disease if I don't have a doctor?

What can I use for cushing disease if I don't have a doctor?

Need a doctor: Cushing's disease is treated with surgery or prescription medications. There is no over the counter or natural/herbal way to treat this disease. It's a very difficult diagnosis to make and even with a doctor who specialized in this disease, it will take many tests to come up with a definitive diagnosis. ...Read more

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In what way is cushings disease diagnosed?

Overnight: Do an overnight Dexamethasone suppression test: draw serum cortisol in the morning. Then take 1 mg of Dexamethasone at bedtime and repeat the serum cortisol the next morning. Failure to suppress is indicative of cushing's disease. ...Read more

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What's cushings disease?

ACTH from pituitary: By definition this is caused by an acth-producing tumor that causes the adrenal glands to overproduce cortisol. Any cause of too much cortisol or some other substance with cortisol-like activity will produce obesity, hypertension, glucose intolerance / high blood sugar, mood changes, immune compromise, and red face (c's syndrome). This is always serious and you need a skilled physician. Good luck. ...Read more

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What does untreated cushings disease cause?

Cushings Disease: Most people have upper body obesity, a rounded face, increased fat around the neck, and relatively slender arms and legs. Children tend to be obese with slowed growth rates. Skin becomes fragile and thin, bruises easily, and heals poorly. Purple or pink stretch marks may appear the bones are weakened. Women show increased hair growth and menstrural irregularities. High blood pressure. ...Read more

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What effect does cushings disease have on rib fractures?

What effect does cushings disease have on rib fractures?

Thin bones: Osteoporosis can occur in Cushing's syndrome due to excess corticosteroid levels and this leads to more bone thinning and possible fractures. ...Read more

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What are the symptoms of cushing's disease?

Fat redistribution: Weight gain, but especially a shift of fat to the abdomen, shoulder. "buffalo hump". Purplish striae (stretch marks) on skin; acne. Diabetes, hypertension, muscle weakness. In women, loss of periods, excess hair growth. Many people will have some of these symptoms. If your doctor is suspicious, the screening tests are not difficult to perform. ...Read more

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Difference between cushing disease and syndrome ?

Difference between cushing disease and syndrome ?

Disease vs. syndrome: Hi. Cushing's disease is specifically hypercortisolism due to an ACTH-secreting pituitary adenoma. Cushing's syndrome is simply the clinical manifestations of hypercortisolism, and (once you know it's not pituitary) can be due to adrenal tumors (benign or malignant), exogenous glucocorticoid therapy, or a paraneoplastic syndrome (cancers that secrete ACTH or CRH). ...Read more

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What choices do I have for treating cushing disease?

What choices do I have for treating cushing disease?

Options: Cushing's disease is different than cushing's syndrome. Cushing's disease is caused by a tumor or enlargement (hyperplasia) of the pituitary gland. The best treatment is to take it out through surgery. If the surgery is incomplete, radiation treatment can then be used. Lastly, if these treatments are not successful, the adrenal glands may need to be removed to stop the production of cortisol. ...Read more

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What is the definition or description of: cushing disease?

What is the definition or description of: cushing disease?

ACTH secreting tumor: Cushing disease is excessive cortisol production due to an acth secreting pituitary adenoma. Acth stimulates the adrenals to produce excessive cortisol, leading to central obesity, lack of growth in children, high blood pressure, hyperglycemia, muscle weakness and skin fragility. It can also cause low bone density. ...Read more

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Is it bad luck or bad genes that made me develop cushing disease?

Is it bad luck or bad genes that made me develop cushing disease?

Not your fault: Quoting dr. Loh:primary cushing's syndrome is the result of an endocrine active mass of adrenal gland cells that become so not as a result of lifestyle habits (good or bad). It's not your fault, but fortunately often completely curable. There are secondary cushing's syndromes related to medications doctors give to treat certain conditions, and it becomes a balance of benefits vs. Risks. ...Read more

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Kids' favorite aunt came to visit. Told me she has cushing disease. What should I tell my children?

Kids' favorite aunt came to visit. Told me she has cushing disease. What should I tell my children?

Rarley hereditary.: Usually due to a small mass in the pituitary gland in the brain that screats high level of special hormone that increase the production of cortisol from the adrenal glands. It cause multiple problems it increase weight , blood glucose , blood pressure causes osteoporosis. It is rarely hereditary and should not worry the kids that they may get it. ...Read more

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When I was little, my parents said I had cushing disease. I don't know many others who have had it. What is it?

When I was little, my parents said I had cushing disease. I don't know many others who have had it. What is it?

Excess cortisol : Cushing's disease is very uncommon. It is a pituitary tumor that makes a hormone (acth) that stimulates the adrenal gland to make excess cortisol. The treatment is pituitary surgery, sometimes followed by radiation and/or meds. Cushing's syndrome is excess cortisol from any cause - steroid use, adrenal mass or cushings disease. Symptoms are same-obesity, thin fragile skin, easy bruising, etc. ...Read more