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Doctor insights on: What Is Cushing Disease

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What is cushing disease ?

What is cushing disease ?

Disease vrs Syndrome: Cushing disease, which is hypercortisolism caused by an acth-secreting pituitary adenoma, is the most common cause of cushing syndrome, and is responsible for 60% to 70% of cases. Cushing syndrome is mainly caused by other sources of corticosteroids like the medicines dr prescribe to treat many conditions ( prednisone, medrol, (methylprednisolone) solumedrol, (methylprednisolone) deposed rol, etc) commonly in copd, asthma, allergies. ...Read more

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Dr. Linda Callaghan
41 doctors shared insights

Cushing Disease (Definition)

Cushing disease is excessive cortisol production due to an acth secreting pituitary adenoma. Acth stimulates the adrenals to produce excessive cortisol, leading to central obesity, lack of growth in children, high blood pressure, hyperglycemia, muscle weakness and skin fragility. It can also ...Read more


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What is cushing's disease?

What is cushing's disease?

Pituitary tumor: Cushing's syndrome is any conditions that cause the adrenal gland to produce too much cortisol. Cushing's disease is a adenoma (tumor) in the pituitary that produces a hormone called acth which causes the adrenal gland to produce too much cortisol. ...Read more

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What is ?Cushing's disease?

What is ?Cushing's disease?

Pituitary ACTH: Cushings syndrome is a clinical syndrome produced by excess cortisol in the body. Cushings disease is one of the potential causes of the syndrome in which a benign pituitary tumor secretes an excess of acth (adrenocorticotropic hormone) this stimulates adrenal secretion of excess cortisol and produces cushings syndrome. ...Read more

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What sort of disorder is cushing disease?

Cushing's disease: Cushing's disease is a condition where the pituitary (tumor) is producing too much acth (adrenalcorticotropic hormone). This hormone stimulates your adrenal glands to produce extra cortisol (stress hormone) which in excess can cause a lot of metabolic problems. ...Read more

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What are the symptoms of cushing disease?

Many symptoms: Symptoms / signs: truncal obesity (mr. Potatohead look), "moon" facies, thinning of skin, easy bruising, "buffalo" hump in upper back, purple stretch marks, hypertension, fatigue, psychiatric sx, insomnia, excess hair growth, muscle weakness and loss. Symptoms are often progressive and should prompt screening. ...Read more

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What exactly is Cushing's disease?

What exactly is Cushing's disease?

Pituitary tumor: Cushing's syndrome is any conditions that cause the adrenal gland to produce too much cortisol. Cushing's disease is a adenoma (tumor) in the pituitary that produces a hormone called acth which causes the adrenal gland to produce too much cortisol. ...Read more

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What can I use for cushing disease if I don't have a doctor?

What can I use for cushing disease if I don't have a doctor?

Need a doctor: Cushing's disease is treated with surgery or prescription medications. There is no over the counter or natural/herbal way to treat this disease. It's a very difficult diagnosis to make and even with a doctor who specialized in this disease, it will take many tests to come up with a definitive diagnosis. ...Read more

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In what way is cushings disease diagnosed?

Overnight: Do an overnight Dexamethasone suppression test: draw serum cortisol in the morning. Then take 1 mg of Dexamethasone at bedtime and repeat the serum cortisol the next morning. Failure to suppress is indicative of cushing's disease. ...Read more

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What's cushings disease?

ACTH from pituitary: By definition this is caused by an acth-producing tumor that causes the adrenal glands to overproduce cortisol. Any cause of too much cortisol or some other substance with cortisol-like activity will produce obesity, hypertension, glucose intolerance / high blood sugar, mood changes, immune compromise, and red face (c's syndrome). This is always serious and you need a skilled physician. Good luck. ...Read more

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What does untreated cushings disease cause?

What does untreated cushings disease cause?

Cushings Disease: Most people have upper body obesity, a rounded face, increased fat around the neck, and relatively slender arms and legs. Children tend to be obese with slowed growth rates. Skin becomes fragile and thin, bruises easily, and heals poorly. Purple or pink stretch marks may appear the bones are weakened. Women show increased hair growth and menstrural irregularities. High blood pressure. ...Read more

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