Doctor insights on:
What Is Considered Treatment Resistant Depression
Failure of one med: Treatment-resistant depression (TRD) typically refers to inadequate response to at least one antidepressant trial of adequate doses and duration. TRD is a relatively common occurrence in clinical practice, with up to 50% to 60% of the patients not achieving adequate response following antidepressant treatment. ...Read moreSee 1 more doctor answer
Depression is a mood disorder that can affect behavior and emotions. Symptoms of depression include feeling down most of the time, losing interest in previously enjoyable activities, increase or decrease in appetite or weight, sleeping more or less, becoming easily agitated or lethargic, feeling worthless, feeling guilty, having difficulty concentrating, thinking more about death and dying. Depression can sometimes result in suicidal thoughts and plans. In this case, emergent ...Read more
Yes: But the definition is usually failure of 2-3 different treatments. Treatment-resistant doesn't mean incurable. Very often people have gotten multiple antidepressant trials without much benefit, but they were all similar medications or too short trials. There are many strategies and combinations as well as ECT that often work when others fail. See my book, psychiatry in techno colors. ...Read moreSee 1 more doctor answer
No 1 "best" one: There are many treatment augmenting strategies for treatment resistant depression. One that seems promising but has less side effects is l-methyl folate (folic acid), (folic acid) since many with depression have abnormalities of folate (folic acid) metabolism that can worsen depression. Also there are transcranial magnetic stimulation and ect. Ongoing psychotherapy of course. Plus many complementary forms of medicine as well. ...Read moreSee 2 more doctor answers
Depression: may be treated with different classes of antidepressants( selective serotonin reuptake inhibitors, serotonin-norepineprhine reuptake inhibitors, mood stabilizers, atypical antipsychotics & bupropion. Tricyclic antidepressants and monoamine oxidase inhibitors are often used off- label now (rather than for depression). Treatment option include > ...Read moreSee 1 more doctor answer
What is your advice regarding divorcing while having major treatment resistant depression? Could it help the depression?
Uncertain: Divorce can have both effects on depression. It really depends on the marriage and the depression. I strongly recommend talking with a psychotherapist at length before making the decision to divorce and perhaps consider couples counseling in addition to individual therapy for yourself. Major depression and marital dissatisfaction are separate entities that can/do contribute to each other. ...Read moreSee 2 more doctor answers
How is the success of Lithium Therapy in Atypical depression?suffering from unipolar treatment resistant depression.
What is the current thinking on BPD and treatment resistant depression? Is there anything new in the pipeline at the moment?
BPD ?: KatieM881~ here are some references for you to read for latest treatment for BPD: http://bipolar.stanford.edu/documents/3.WangNewBP.Rx.MoodD.EdDay10.Final.pdf http://www.nimh.nih.gov/news/science-news/science-news-about-bipolar-disorder.shtml https://www.seroquelxrtouchpoints.com/bipolar-disorder/bipolar-depression-efficacy?source=SERH34439&WT.mc_id=SERH34439&umedium=paid%20search&uadpub=google ...Read more
How is the tolerability and adverse effect of Moclobemide in treatment resistant depression?if other options didn't work.
VNS for dep: Yes. I've heard of it, been to a conference on it, and heard dinner programs about it. It is exorbitantly expensive and was considered the end of the line treatment for depression a few years back. In my opinion, tms and some of the newer agents may work just as well. ...Read moreSee 1 more doctor answer
Do you guys have experience in giving out alternative medicine for treatment resistant depression such as modvigil or memantine or something else?
At low dose Abilify activates ?in unipolar Treatment-resistant depression.one Dr@healthtap said at low doses aripiprazole activates! best regards.
Do any psychiatrists have experience using ketamine for treatment resistant depression? This seems to be a growingly popular and relatively successful treatment / approach.
Short term: This is a short term treatment, and has to be repeated in a few days or weeks depending on how long the effects last for you. it has not been FDA approved for long term treatment, and has to be given as an infusion in a monitored setting. It does however act fast, as soon as you get it, which is why it has been looked at as an alternative to traditional SSRIs that take weeks to start working. ...Read moreSee 5 more doctor answers
Does long-term use of amphetamine have any consequences, other than hypertension? Nothing else helps my treatment resistant depression.
I have long-term, treatment-resistant depression, and adult add. My add meds always stop working. Any new add meds i could ask about?
Many options: Not long ago, one medication for ad/hd (stimulants) was used. Today, multiple completely different medicines (with unique mechanisms of action). Behavioral therapies and use of assistive technologies on the web and in smatphones can also make a big difference. Some evidence shows neuro-training and biofeedback approaches to be promising. Talk with your primary doc about an ad/hd specialist. ...Read more
It is for treatment-resistant depression, but there are no psychiatrists using ketamine nearby, so seeking any anesthesiologists near 32159.
Fore treatment-resistant depression. No local psychiatrists prescribe it, so seeking anesthesiologists or pain management physicians .
Do any of you know anything about T3 (liothyronine) treatment for fibromyalgia, CFS, treatment-resistant depression, and/or PCOS?
Not recommended: This is fringe practice that is not supported by endocrinologists, who are the experts in hormones. I have seen people get very sick from improper use of thyroid hormone for things it was not meant to treat, and outside the scientifically established parameters for its use. There are very few scientifically valid reasons to use T3 (liothyronine). ...Read more
What should I do to resistant treatment depression? It is so severe and nothing has worked so far I've tried psychotherapy and all kinds of medication and nothing worked...I have been also having really bad phsyical symptoms like sick feeling, burning, st
Thorough physical : You need to get a comprehensive, thorough physical exam first. You may very well have a low thyroid disorder, which may account for the lack of improvement in your illness. You may have a malabsorption disorder. You may need ECT or similar treatment. Maybe maoi's. I recommend going to a local medical school department of psychiatry for a referral for a psychiatrist for a second opinion. ...Read moreSee 3 more doctor answers
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