Doctor insights on:
What Is Celiac
Celiac disease: In Celiac disease the body reacts to gluten (in wheat and gluten like proteins in rye and barley) in the small intestine causing damage. This limits the intestine's ability to absorb some nutrients. Classically people have loose stool, bloating, and abdominal discomfort but more often are just found when screened for other reasons (like symptoms of a nutritional deficiency like iron or bone loss). ...Read more
Celiac Disease: Celiac disease (gluten-sensitive enteropathy) has three of the following features: villous atrophy; malabsorption, weight loss, or other signs of nutrient or vitamin deficiency; and resolution of the mucosal lesions and symptoms after withdrawal of gluten-containing foods (usually within a few weeks to months). Diarrhea, weight loss, and antibodies against gliadin ...Read more
Genetics: If you are born with genetic mutations, hla types dq2 or dq8, this predisposes you to develop celiac disease. Then it is usually an environmental trigger, like abnormal gut microbes or infection that triggers it from being a genetic predisposition into an active condition. The condition starts with damage the microvilli that line the gut and eventually ends with total villous atrophy. ...Read more
Celiac disease: Celiac is an autoimmune condition in which your body makes antibodies against the small intestine; it causes malabsorption of food and often chronic diarrhea, anemia, or occasionally abnormal liver function. The treatment is simply to avoid gluten in foods, but this is not a simple diet to follow. ...Read more
Yes: If you continue to consume gluten with a diagnosis of celiac disease, the gluten will damage the surface of the small intestine thus impairing your ability to absorb many nutrients leading to weight loss. However, you need to consult your doctor to document the diagnosis since there are other conditions which can cause unexplained weight loss. ...Read more
Probably same: An allergy may give you more symptoms but celiac usually attacks the digestive tract. ...Read more
Gut 1st, then.....: Immune reaction to gluten, causes infl in small bowel, loss of villi, loss of absorption, leads to vitamin and mineral deficiency (calcium, iron, d, others). Causes gas, bloat, cramps, diarrhea, fatigue, weakness. May cause joint, neural, liver, fertility, other abnormalities. Untreated, over time, can increase risk for osteoporosis, lymphoma of bowel, esophageal cancer. ...Read more
Hard to speculate: Some Gluten sensitive pts with irritable bowel syndrome or other obvious symptoms will not clear on a rigid gluten free diet. The prior gut tissue injury may predispose them to other food sensitivities, or they may just be intolerant to things. Many are intolerant to #40 red dye or other artificial dyes. Other food sensitivities would need to be tested individually to sort out the problem ones ...Read more
Chronic pain : Celiac plexus block is when local anesthetic is injected into a nexus of nerves located in the abdomen. It is used to treat chronic pain from cancer in the upper abdomen or it can be used to treat chronic pancreatitis. The chronicity is important because there are many potential complications. A proper diagnosis for the cause of the abdominal pain must be made prior to having this block. ...Read more
Depends...: If the test was performed to identify whether you have celiac disease, an unequivocally elevated ttg value is diagnostic for celiac disease. If you are IgA deficient, and the only ttg assayed was iga, you may miss a diagnosis of celiac disease due to a falsely negative result. If you have celiac disease, ttg can be used to assess how compliant you may be with strict dietary gluten avoidance. ...Read more
Anti-transglutaminas: Antibodies that bind to transglutaminase could indicate the presence of celiac disease. This is a sugggestive test only. Negative testing does not definitively rule-out celiac dz and positive testing does not confirm the diagnosis. An intestinal biopsy would be the most helpful test. ...Read more
Unusual: This often means bleeding in the intestines. See a doctor immediately. ...Read more
Peripheral neuropathy (burning, tingling or numbness in hands or feet) is a relatively common finding in celiac disease and may predate other manifestations. Of concern, although it may 'just' be associated with nutritional deficiences, it 'can be' associated with lymphoma. Please be evaluated.
Gltuen-free diet will not improve the neuropathy — but may prevent further deterioration. ...Read more
What are symptoms of celiacs disease and am I more likely to have it because my grandfather does?
Variable Sx; slight: Celiac can have variable sx, incl gas, bloat, diarrhea, wt loss, rarely gain, constipation, joint aches and pains (often from vitamin d def), fatigue (often from iron def), osteoporosis, swallowing probl, rarely liver probl. Can get screened with blood testing, and/or genetic testing. Assoc with other autoimmune diseases such as ibd, psoriasis, rheum arth, lupus, type 1 diabetes, thyroid disease. ...Read more
Bloodwork: Celiac disease is usually screened for (in the right patient) with blood tests. Depending on the results of these blood tests, you may be referred to a gastroenterologist to get a biopsy to confirm the diagnosis. You have to be on a regular diet (not gluten-free!) for these tests to be valid. ...Read more
connective tissue :
Connective tissue disease: test for sjogren's (blood & sialogram) autoimmune thyroid, explore with your doctor : omeoprazole & Erythromycin & domperidone. Botox injections into pylorus muscle for stomach pain and nausea.
Avoid raw veggies, grind food up when things are very bad.
There does not need to be one primary autoimmune disorder. ...Read more
Gastrointestinal symptoms include:
abdominal pain, bloating, gas, or indigestion
decreased appetite (may also be increased or unchanged)
diarrhea, either constant or off and on
lactose intolerance (common when the person is diagnosed, usually goes away after treatment)
nausea and vomiting
stools that float, are foul smelling, bloody, or fatty. ...Read more
Strict gluten free..: Gluten free diet can be difficult. Research hidden sources of gluten, be diligent about gluten contamination from food prep of other household members, and very careful about dining out. It may take as long as 6-12 months for your small bowel damage to heal. Keep in constant contact with your GI specialist. If you aren't feeling better, additional evaluation may be necessary. ...Read more
Abdominal discomfort: Individuals with celiac disease can have a variety of different symptoms and may even be asymptomatic. Often it is associated with gastrointestinal distress including pale stools that are associated with non-specific diarrhea, cramping, and bloating. The diagnosis can only be made by a physician. If symptoms improve with a gluten free diet, the chances of having celiac disease are greater. ...Read more