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Doctor insights on: What Is Carcinoma In Situ

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What causes ductal carcinoma in situ (dcis)?

What causes ductal carcinoma in situ (dcis)?

Viral insertion: DCIS is the earliest phase of transformation to malignancy developing in the ductal system before invasion into parenchyma has occurred. It is defined on mammo by clustered microcalcification. In general the long terminal repeat of the MMTV viral genome enters the ductal cell to initiate transformation. with time the cells become aggressive and invade basement membrane helped by the EBV virus ...Read more

Dr. Barry Rosen
4,310 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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What is the definition or description of: carcinoma in situ?

What is the definition or description of: carcinoma in situ?

Depends: Depends on where this diagnosis was made. Is a non-invasive disease. Ductal carcinoma in situ of the breast is treated with lumpectomy and sometimes hormone therapy & radiation. Lobular carcinoma in situ of breast is treated as a benign pre-cancerous lesion. Cancer in situ of the colon treated as an early cancer with surgery. Gynecologist can answer this for a cervix lesion. ...Read more

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Whats the difference between carcinoma in situ and cin?

Whats the difference between carcinoma in situ and cin?

Since no one has: Answered in a week, i think it is because like me, they do not know what cin is. We all know that carcinoma in situ means the cancer is superficial, not invading through a structure, and generally conveying risk of becoming invasive cancer. This is most prevalently used in breast cancer. However, i cannot contrast to cin. I do not know what that is. ...Read more

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I was wondering are precancerious polyps carcinoma in situ?

I was wondering are precancerious polyps carcinoma in situ?

Not necessarily: Most precancerous polyps of the colon are considered adenomas. These can progress to contain areas of severe dysplasia and/or carcinoma in situ which mean that they are one step closer to becoming malignant. ...Read more

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I was diagnosed with anal carcinoma in situ twice what are the chances that it will reoccure?

I was diagnosed with anal carcinoma in situ twice what are the chances that it will reoccure?

Unfortunately High: Anal carcinoma in situ is a rare pre-cancerous condition that often will recur. It may be associated with HIV and is usually directly caused by hpv. Sometimes close observation by anal "mapping" every 3-4 months is enough with small operations to remove any new lesions as needed. In other instances, treatment with imiquimod, laser therapy or radiation therapy might be recommended. ...Read more

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Hpv now sever/carcinoma in situ not sure if it spread yet, how to know?

Hpv now sever/carcinoma in situ not sure if it spread yet, how to know?

If you know you: Have HPV, and now have dysphasia, time to visit Gyn Onc to discuss options if you would like to avoid hysterectomy now. ...Read more

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What would confirm the diagnosis of carcinoma in situ of the large intestines?

What would confirm the diagnosis of carcinoma in situ of the large intestines?

Biopsy: A colonoscopic biopsy would be necessary to make the diagnosis of colon cancer. It is the gold standard. Good luck. ...Read more

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I need to know what is treatment for extensive high grade ductile carcinoma in situ?

Excision and XRT: The standard treatment for high grade dcis is complete excision of the abnormal area(calcification and any palpaable tumor) followed by radiotherapy on recovery from surgery. It is best to then take tamoxifen as adjuvant therapy for 5 years. Good luck. ...Read more

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How are carcinoma in situ and benign neoplasm different?

Good question: And difficult to tell sometimes. The most straightforward way to put it is that a benign neoplasm will never turn into an invasive malignancy within your lifetime. Cis will eventually turn into one. But, because we don't live forever, cis might not turn into a malignancy during one's lifetime anyway. Pathologists can usually, but not always, tell the difference by microscopic cell exam. ...Read more

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Is cervical carcinoma in situ considered cancer or pre cancer?

Is cervical carcinoma in situ considered cancer or pre cancer?

Pre- cancer: It is good to seek treatment from a gynecologist as it will require some form of local therapy to either excise it or burn it off with Laser or cryotherapy. if done well it can be easily eradicated. ...Read more

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The decision was that I have lobular carcinoma in situ. What is it?

The decision was that I have lobular carcinoma in situ. What is it?

Also called lobular: Neoplasia...It forecasts that you will develop a breast cancer in either breast. Some used to do "mirror" biopsies. Others contemplate bilateral mastectomy. Lcis is a risk not a cancer, but the lobular invasive cancer can pose detection problems. Discuss this with a breast cancer team. I would watch very carefully. Lobular cancer makes up only 15% of invasive cancer. ...Read more

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When doctors say ductal carcinoma in situ, what does "in situ" mean?

When doctors say ductal carcinoma in situ, what does "in situ" mean?

"in place": Ductal carcinoma in situ (DCIS) of the breast is a breast cancer which has started in the ducts of milk glands (as most breast cancers do) but not yet invaded beyond that into the fat of the breast. Untreated, it has a high likelihood of becoming invasive breast cancer, a potentially fatal disease. Treated DCIS has a high cure rate. Some with DCIS benefit from taking med to prevent 2nd cancer. ...Read more

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How long does it take to go from carcinoma in situ to cervical cancer?

How long does it take to go from carcinoma in situ to cervical cancer?

Not all invasive: Cancers start in situ, and not all in situ cancers ultimately invade...But a lot do. So, there is no timetable of when that you can rely on. It is reasonable to take care of in situ when you find it, rather than trust an unreliable actor to behave itself the way you might like. ...Read more

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What treatments can you get for ductal carcinoma in situ?

What treatments can you get for ductal carcinoma in situ?

More info needed: Surgery, radiation, hormonal pill. More info needed on size and extent of disease. ...Read more

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Are there natural treatments for lobular carcinoma in situ?

Yes BUT: We need to consider that this is probably lobular "neoplasia" vs. Cis. That being said we still feel this is marker of increased cancer risk. We shouldn't neglect putting together fam history, other risk factors, limitations & risks in imaging, etc before discounting antihormonal therapy and rarely surgery. Many do choose close follow-up. Natural treatments may be incorporated with sufficient data. ...Read more

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What are the treatments for invasive ductal carcinoma in situ?

INVASIVE or DCIS?: These terms are incongruous: dcis is, by definition, breast cancer that has not "broken out" of the ducts and entered the adjacent supportive tissue of the breast; invasive, or infiltrating ductal cancer, by definition, has. The treatment of these 2 diseases is quite different since there is a risk of systemic disease with the latter. Please clarify, thanks. ...Read more

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What is the usual prognosis and treatment for ductal carcinoma in situ?

What is the usual prognosis and treatment for ductal carcinoma in situ?

Excellent Prognosis: Dcis is usually treated with a combination of surgery followed by radiation therapy. The local control rates approach 100% this way. Cosmetic outcome is usually good to excellent and treatment itself is generally well tolerated. ...Read more

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Please tell me how long it takes for to go from CIN 3 (carcinoma in situ) to cervical cancer?

I don't know: We were often reminded during pathology training that tumors don't read books. It best to see your doctor, and complete a course of treatment. The cells in cin3 look a lot like the cells in invasive cancer. I wish you the best. ...Read more

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Can you have low grade superficial bladder cancer then in 6 months develope carcinoma in situ if the bladder. Is that a recurrance or a new cancer?

Can you have low grade superficial bladder cancer then in 6 months develope carcinoma in situ if the bladder.    Is that a recurrance or  a new cancer?

Yes and no: Bladder cancers arises multifocally. By the time that the first cancer appears, the entire epithelium covering the bladder already bears mutations, and new cancers begin popping up in various places. They are part of the same underlying process although they are individual cancers. This is a tricky concept. I'm glad your disease was detected and hope that you'll get a good outcome. ...Read more

Dr. William Singer
43 doctors shared insights

Carcinoma In Situ (Definition)

Depends on where this diagnosis was made. Is a non-invasive disease. Ductal carcinoma in situ of the breast is treated with lumpectomy and sometimes hormone therapy & radiation. Lobular carcinoma in situ of breast is treated as a benign pre-cancerous lesion. Cancer in situ of the colon treated as an early cancer with surgery. Gynecologist can answer this ...Read more


In Situ (Definition)

Means localosed in place. Medical terms is for carcinoma "localized and did not spread out" it is really description of precancerous condition with bad name that disturbs many patients. Carcinoma in situ is not a killer. If left untreated will develop into invasive cancer ...Read more