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Doctor insights on: What Is A Thyroid Follicular Lesion

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Dr. Linda Callaghan
13 doctors shared insights

Thyroid (Definition)

The thyroid is an endocrine gland that sits in the lower part of the neck. It produces thyroid hormone - which ...Read more


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Cana follicular thyroid lesion turn malignant?

Cana follicular thyroid lesion turn malignant?

Follicular cancer: Follicular thyroid cancer the second most common cancer, after papillary. A thyroid nodule over 2.0 cm, positive/suspicious fna or symptoms are indications for thyroid lobe resection. Final pathology is often where a cancer diagnosis is made. Follicular thyroid cancer is treatable and has a good prognosis. So yes, it can turn into cancer, you need to be monitored closely. Okay to see surgeon. ...Read more

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Is a "follicular lesion of unknown origin" of the thyroid considered supsicious for cancer?

Is a "follicular lesion of unknown origin" of the thyroid considered supsicious for cancer?

Yes: Maybe the actually diagnosis is "follicular lesions of undetermined significance", which is a very common diagnosis using the new bethesda system. If i had one of these in my neck, i'd be really eager to have it out, but there are variables and your physicain will talk with you about this. ...Read more

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Two thyroid fnas with the result being "follicular lesion of undetermined significance". What should the next step be?

Two thyroid fnas with the result being "follicular lesion of undetermined significance". What should the next step be?

Gene profiling..: For FLUS diagnoses, the current recommendation is to perform molecular analysis of cells removed at the time of FNA; there are two tests, Afirma by Veracyte, and the other test by Asuragen. These are expensive tests, make sure the insurance company covers it. Some endocrinologists do only one or the other test. Please check with your endo. ...Read more

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I had two thyroid fnas done three weeks apart and both say "follicular lesion of undetermined significance". What happens next? Why did i get that?

I had two thyroid fnas done three weeks apart and both say "follicular lesion of undetermined significance". What happens next? Why did i get that?

Indeterminate nodule: There is a standardized reporting system (bethesda) for thyroid fnas. 5 categories (benign, atypia of undetermined significance, neoplasm, suspicious for malignancy, malignant). Your result is in the second category. Studies place the probability of malignancy for your result at 5-20%. There are labs (afirma) that do gene expression testing on these samples to better define the risk of cancer. ...Read more

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Does mild intrinsic vascularity mean anything on a solid micro follicular thyroid lesion which is circumscribed and heterogeneous?

Does mild intrinsic vascularity mean anything on a solid micro follicular thyroid lesion which is circumscribed and heterogeneous?

Possibly: I want to clarify your description. You wrote a micro follicular lesion.This is an older pathology dx. Was this biopsied or is this a micronodule (<1 cm). Well circumscribed is good.Heterogeneous nod need to know the character of the solid part.After the other info, increased blood flow is a risk factor cancer (but now considered a minor factor). Thyroid func is key here. W/more info FNA or not ...Read more

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What exactly does the terms circumscribed and heterogeneous actually mean relating to a solid thyroid micro follicular lesion. Flus on biopsy. ?

What exactly does the terms circumscribed and heterogeneous actually mean relating to a solid thyroid micro follicular lesion. Flus on biopsy. ?

Good signs: Circumscribed lesion on thyroid ultrasound means that the lesson is encapsulated and that this is a good sign . Heterogenous mean that the lesion has various areas of increased and decreased density and that is also a good sign . however follicular lesions are indeterminant and could be malignant . ...Read more

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Thyroid follicular lesion 2.4cm solid circumscribed with mild vascularity.Thyroseq pending Can this test show a definite benign? what's circumscribed

 Thyroid follicular lesion 2.4cm solid circumscribed with mild vascularity.Thyroseq pending Can this test show a definite benign? what's circumscribed

Need FNA: Only biopsy will give definitive answer , it it is benign or malignant. Most likely your doctor will recommend fine needle aspiration ( FNA ) biopsy a simple out patient procedure Follow the advise of your doctor. ...Read more

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Is surgery recommended if thyroid fna results are follicular lesion of undetermined significance? Should I get second fna?

Is surgery recommended if thyroid fna results are  follicular lesion of undetermined significance? Should I get second fna?

Yes: A follicular lesion identified on fine needle aspiration generally does warrant a thyroid lobectomy because a follicular cancer can not be ruled out. The architecture of the tissue is necessary to distinguish a benign from a malignant follicular lesion, and this can not be obtained with an fna. Repeat fna will not help. ...Read more

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I have bilateral partially cystic thyroid nodules.Biopsy done of the larger one, came back "follicular lesion of unknown origin" what does that mean?

I have bilateral partially cystic thyroid nodules.Biopsy done of the larger one, came back "follicular lesion of unknown origin" what does that mean?

Variable meaning: Follicular?patterned lesions of the thyroid are common; these include hyperplastic/adenomatoid nodules, follicular adenoma, follicular carcinoma and follicular variants of papillary carcinoma. Repeat biopsy with a sample sent for a genetic afirma assay may give additional useful information. In addition, discuss with your endocrinologist. ...Read more

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My thyroid nodule report says rare macrophages and colloid consistent with follicular lesion of undetermined significance. Foll...lesion can't exclude?

Follow advice of end: Your Endocrinologist can guide you best. Your biopsy appears to be inadequate to make a definite diagnosis. Future follow up with an endocrinologist is advised so that your thyroid can be monitored for any further growth of this nodule which is easy to do with an ultrasound. ...Read more

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Thyroid biopsy results Showing minute fragment of thyroid tissue w/ hemosiderin-laden macrophages & blood elements most consistent w/follicular lesion?

Thyroid biopsy results Showing minute fragment of thyroid tissue w/ hemosiderin-laden macrophages & blood elements most consistent w/follicular lesion?

Thyroid biopsy: What is your question? Sounds to me like you have a lesion of the thyroid follicle. But they may have missed something else. Why was biopsy being done? Take to the Dr who did it as they know you best. ...Read more

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A fna on a thyroid nodule came back as "follicular lesion of undetermined significance". What does that mean and what happens next?

A fna on a thyroid nodule came back as "follicular lesion of undetermined significance". What does that mean and what happens next?

Thyroid tumors: In hyperthyroidism are rare. If the index of suspicion is low, repeat sonogram in a few. Omths, ofherwise proceed with an open biopsy. Make sure you are nit taking too much merhimazole. ...Read more

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What do these biopsy results of thyroid nodule mean ATYPIA OF UNDETERMINED SIGNIFICANCE OR FOLLICULAR LESION OF UNDETERMINED SIGNIFICANCE?

Re-FNA in 3-6 Months: Hi Jami, AUS/FLUS is a term that cytopathologists use for thyroid nodules that they basically are "unsure" about. Classic management for this diagnosis is to have a second repeat FNA in 3-6months. Nowadays though high tech molecular pathology tests can sometimes divide AUS/FLUS definitively into benign and malignant categories. Please setup a virtual consult with me for more information. ...Read more

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Result from thyroid fna: indeterminate follicular lesion. Is the indeterminate description common? Waiting now for genetic test results (2 more weeks)

Result from thyroid fna: indeterminate follicular lesion. Is the indeterminate description common? Waiting now for genetic test results (2 more weeks)

All too often!: Sadly, indeterminate results can be up to 60%! should be <10%! search "quality improvement in thyroid fna" for articles. This due to the skill levels of individuals doing the biopsy, preparation and interpretation. Genetic tests may help but are often non-specific, expensive and take a long time. Ask ...It is fine to shop around for best performers. Patients have the right to demand high quality. ...Read more

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Could it be cancer? My thyroid levels have been off so they did the ultrasound and found nodules.Thyroid biopsy results showing follicular lesion

Could it be cancer? My thyroid levels have been off so they did the ultrasound and found nodules.Thyroid biopsy results showing follicular lesion

You need an expert: A Thyroid specialist can help you to determine if the nodules in your Thyroid are benign or Cancerous. Ask your doctor to refer you to an endocrinologist. A second opinion always helps if your doctor has not been able to sort things out for you clearly . ...Read more

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1 CM solid node l thyroid lobe a mixed micro and macro- follicular lesion fna consists of follicular cells in small follicles microfollicles & small sheets displaying extensive hurthle cell changes ?

Now benign: From your information it isa benign adenoma , hurthle cell are little larger pinkish cell , but have higher incidence of malignant transformation than follicular , to hurthle cell carcinoma , unlike follicular , it will spread to lung , bone etc, follow your doctor's advice. ...Read more

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3 thyroid nodules, hypoechoic solid nodule with few tiny calcified 1st FNA is benign follicular lesion and 2nd is benign follicular nodule,possible?

Thyroid follicles: Most likely, the ultrasound is picking up benign follicular cysts, or areas of "colloid" (where thyroid hormone is made) arranged in a circular pattern or nodule. From the description (& the 2 FNA biopsies) it's unlikely to be cancer. In certain parts of the world (40% of it), iodine deficiency is common & thyroid nodules are prominent. http://www.mayoclinic.org/diseases-conditions/thyroid-nodules ...Read more

Dr. Scott Bolhack
802 doctors shared insights

Wounds (Definition)

Wound = injury to tissue. May include ...Read more