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Doctor insights on: What Is A Serotonin Reuptake Inhibitor

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What is a gaba reuptke inhibitor?

What is a gaba reuptke inhibitor?

Anti-convulsant: Some drugs that are used to treat seizures are GABA reuptake inhibitors. GABA is an inhibitory neurotransmitter and has an anti-seizure effect. These drugs reduce the reuptake of GABA into neurons and glia thereby increasing the amount of GABA available to interact with GABA receptors. ...Read more

Serotonin (Definition)

Serotonin is a chemical derived from the Amino Acid tryptophan and acts as a neurotransmitter (communicating ...Read more


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What is the definition or description of: selective serotonin reuptake inhibitor?

What is the definition or description of: selective serotonin reuptake inhibitor?

SSRI's: Selective serotonin re-uptake inhibitors or serotonin-specific reuptake inhibitor are a class of compounds typically used as antidepressants in the treatment of depression, anxiety disorders, and some personality disorders. ...Read more

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What does "selective" mean in selective serotonin reuptake inhibitor?

What does "selective" mean in selective serotonin reuptake inhibitor?

Just one type: "selective" in this case refers to the fact that the previous generation of antidepressants, the tricyclics, worked on all 3 of the neurotransmitters in the brain thought to be involved in depression in varying degrees; serotonin, norepinephrine, and dopamine. Prozac, (fluoxetine) and the other ssris act almost entirely on serotonin. ...Read more

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What is a excitatory synapse?

What is a excitatory synapse?

Neuron junctions.: Synapses are junctions between neurons, or nerve cells. Nerves transmit signals throughout the body, & synapses are gates where chemical signals are transduced to electrical ones. Synapses may be simply described as excitatory or inhibitory, and often depends on the neurotransmitter involved. For example, excitation of the heart and inhibition of the gut are part of the fight or flight response. ...Read more

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Could viibryd (vilazodone hydrochloride) potentially help ocd...And is it the strongest ssri ti hit serotonin receptors because of its dual action?

Could viibryd (vilazodone hydrochloride) potentially help ocd...And is it the strongest ssri ti hit serotonin receptors because of its dual action?

Choices, choices: The options could really drive anyone mad - not to mention an ocd sufferer. Some like it, some don't. Here's an opinion. You can find a wide range - just as you can for the other meds. What fits you is what matters. A link: http://chipur.Com/2011/03/01/viibryd-a-new-antidepressant-but-anything-exciting/ best! ...Read more

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Is it Safe to take nardil (phenelzine) a maoi inhibitor with levadopa?

Is it Safe to take nardil (phenelzine) a maoi inhibitor with levadopa?

Contraindicated: Never use this combination of drugs, because of high risk for dangerous interaction (e.g. acute hypertension and adjunctive effect of the medication). Hope it help. ...Read more

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How does strattera (atomoxetine) help for ADHD if it is a norepinephrine reuptake inhibitor , without affecting dopamine ?

How does strattera (atomoxetine) help for ADHD if it is a norepinephrine reuptake inhibitor , without affecting dopamine ?

Don't know!: If straterra is a norepinephrine reuptake inhibitor it increases the norepinephrine level in the brain. Methylphenidate stimulants, used in adhd work that way. In my opinion, straterra which was initially unsuccessfully marketed as an antidepressant is not a first line choice for adhd. ...Read more

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Is buproprion a monoamine oxidase inhibitor (maoi) type of drug?

Is buproprion a monoamine oxidase inhibitor (maoi) type of drug?

No: Bupropion (wellbutrin) inhibits re-uptake of norepinephrine and Dopamine into neurons (nerve and brain cells). It does not inhibit mao, so there are no dietary restrictions or common medication interactions, unlike the the maois. ...Read more

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What is acetylcholinesterase inhibitor?

What is acetylcholinesterase inhibitor?

Blocks the enzyme: Mutliple drugs are available to block the effects of this enzyme which breaks down acetylcholine - essential for muscle movement along with many other functions. Used for myasthenia gravis, alzheimers, glaucoma, etc. ...Read more

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Is luvox (fluvoxamine) the only ssri that is a sigma agonist...And is that why it is better for anxiety..Explain sigma a sigma agonist?

Is luvox (fluvoxamine) the only ssri that is a sigma agonist...And is that why it is better for anxiety..Explain sigma a sigma agonist?

Luvox: Fluvoxamine is FDA approved for the treatment of Obsessive Compulsive disorder. It would have to be used off-label for anxiety disorders. A sigma receptor is a non-opiod receptor that binds to different drugs. Here is an excellent abstract: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3015019/

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What is norepinephrine?

What is norepinephrine?

It is a : Catecholamine made by your body. It can cause an increase in your heart rate and blood pressure. It can be released during the fight or flight response. You might know it as noradrenaline. ...Read more

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Is Depakote a dopamine antagonist?

Is Depakote a dopamine antagonist?

No: According to our current understanding, Depakote work by altering calcium current, sodium channel, and the synthesis and breakdown of gaba, the main inhibitory neurotransmitter in the brain. ...Read more

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Which is more effective? Tricyclics or SSRIs (selective serotonin reuptake inhibitors)?

Which is more effective? Tricyclics or SSRIs (selective serotonin reuptake inhibitors)?

TCA/SSRI: Both are, depending on what they are prescribed for. The difference is in tolerability & side-effects. ...Read more

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Is the selective norepinephine reuptake inhibitor, reboxetine, effective ?

Evidence says not: One meta-analysis* (a study pooling results from multiple other studies) suggested that reboxetine is ineffective & may be harmful. *(eyding d et.Al. "reboxetine for acute treatment of major depression: systematic review &meta-analysis of published &unpublished placebo &selective serotonin reuptake inhibitor controlled trials."bmj. 2010; 341:c4737). ...Read more

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How does lyrica (pregabalin) work? Is it similiar to narcotic pain medicine? Or similiar to tramadol as norepinephrine and serotonin reuptake inhibitor?

Lyrica (pregabalin): Dear pika89800 lyrica enhances gaba in the brain and suppresses pain at a cortical level, pain has 3 main levels, local, spinal and brain (cortex), it is non narcotic, it is an antiseizure medication and can sometimes help both pain and anxiety the answer is purely for educational purposes, please contact your md. ...Read more

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What serotonin receptor is most important for depression?

What serotonin receptor is most important for depression?

Way too simplistic: Your brain isn't a 4-cylinder Chevy, where 1 circuit controls 1 function. There are dozens of serotonin receptor subtypes organized into 3 subfamilies. The modulation of mood involves a complex and subtle interplay of excitation & inhibition at multiple receptor subtypes. A neurochemist can spend an entire career researching just 1 receptor subtype. ...Read more

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What happens if I take Zoloft and a mao inhibitor like marplan, nardil, and parnate (tranylcypromine)?

What happens if I take Zoloft and a mao inhibitor  like marplan, nardil, and parnate (tranylcypromine)?

Contraindicated: Taking a monoamine oxidase inhibitor (maoi), such nardil, marplan, or Parnate (tranylcypromine) with a serotonin selective reuptake inhibitor (ssri) such as zoloft is contraindicated. When taken together they can lead to serotonin syndrome. This potentially deadly syndrome may cause agitation or restlessness, fast heart beat, hallucinations, increased body temperature, loss of coordination, and nausea. Seek help! ...Read more