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Doctor insights on: What Is A Paraneoplastic Antibody Panel Supposed To Check For

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Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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All my paraneoplastic antibody panel came back negative. This is a good thing right?

Yes (?): Yes - they aren't positive. However that does not prove a paraneoplastic syndrome isn't occuring. The available antibody tests are not perfect. Also -- no - it doesn' clarify what the problem (that the test was performed to evaluate) is.

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Does Paraneoplastic antibody syndrome blood test through Mayo Clinic is reliable enough?

Does Paraneoplastic antibody syndrome blood test through Mayo Clinic is reliable enough?

Yes: Mayo Clinic Lab is highly reliable, and is one of the best reference labs in the world.

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Why would my dr be ordering a paraneoplastic ab panel if he's not looking for cancer. He's doing a bunch of blood work for possible autonomic dysfu?

Why would my dr be ordering a paraneoplastic ab panel if he's not looking for cancer. He's doing a bunch of blood work for possible autonomic dysfu?

D/w your doctor: You should probably ask your doctor the reasons behind the order. Sometimes, the case are so complicated that possibilities of causes are in wide range and different testings are needed. Since I don't know exactly the case- pick up the phone and ask your doctor. Certain cancer sometimes is associated with different nonspecific symptoms in different body system-paraneoplastic lab is to check on it.

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Is the test for paraneoplastic antibodies clinically useful?

Very much so: Some of the most puzzling clinical syndromes are caused by the immune response to tumors that may not be known to be present yet. There's a group of antibodies for which we can now test that will rule the known syndromes in this category in or out. It's not cheap and isn't to be ordered lightly, but it's a standard part of health care.

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What are the Paraneoplastic antibodies blood tests? Why negative results can not rull out the syndrome?

What are the Paraneoplastic antibodies blood tests? Why negative results can not rull out the syndrome?

Imperfect tests: Paraneoplastic syndromes are uncommon and the presence or absence of antibodies is only one evidence for making the diagnosis. See this site for more info. Uncohttp://www. Ncbi. Nlm. Nih. Gov/pmc/articles/PMC3299076

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If my paraneoplastic ab test came back positive does that mean I have an underlying cancer or will get cancer in the near future?

Paraneoplastic: Paraneoplastic syndrome is a disease or symptom that is the consequence of the presence of cancer in the body. So, if your panel is positive-depending on the sensitivity and the specificity of the panel- your doctor needs to make sure to look for presence of occult cancer in you.

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I have either autoimmune pandysautonomia or paraneoplastic syndrome. My anti striational antibody was positive. I have metastatic thyroid ca. Which?

I have either autoimmune pandysautonomia or paraneoplastic syndrome. My anti striational antibody was positive. I have metastatic thyroid ca. Which?

Complicated: Could be either, and to complicate matters dysautonomia can be cause by a paraneoplastic phenomenon. Either way the primary focus is to first treat the metastqatic thyroid ca and see how the dysautonomia progresses (and hopefully improves).

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Why the antibodies test- paraneoplastic syndrome of mayo clinic and Aetna does not approved by the FDA?

Faulty policy: Many insurances consider certain antibody tests for paraneoplastic syndrome screening involving the nervous system experimental and investigational. They base this on various criteria including debt of research & FDA approval. The tests should be considered medically necessary when ordered selectively for evaluating persons with signs & symptoms of specific paraneoplastic syndromes.

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If you have an intradural, extramedullary spinal tumor and pituitary tumor that cannot be biopsied, would it be prudent to run paraneoplastic ab test or any other blood test to rule out cancer?

If you have an intradural, extramedullary spinal tumor and pituitary tumor that cannot be biopsied, would it be prudent to run paraneoplastic ab test or any other blood test to rule out cancer?

It's not for that: The vast majority of cancers don't produce paraneoplastic antibodies that show on labs. If you've been told that a tissue diagnosis cannot be obtained on either of your two tumors, please think about getting a second opinion, though it may be true. Whatever happens, you deserve to be fully educated about your illnesses.

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Please. Is it true that primary drs can't order auto immune disease panel. The antibodies test. Is it only the specialist can do that?

Please. Is it true that primary drs can't order auto immune disease panel. The antibodies test. Is it only the specialist can do that?

Primary Care: No. It is not true for all physicians. It may be true for yours. We all have our areas of expertise and a good physician will know when they are not the expert. That is why there are specialists.

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2011 hepatiites b antibody positive. Last week hepititas panel negative. Are they the same test and why did they come back different?

2011 hepatiites b antibody positive. Last week hepititas panel negative. Are they the same test and why did they come back different?

Can be confusing: Hepatitis blood tests can be confusing, and explaining it takes more space than available here. There is more than one type of Hepatitis B antibody, so we have to be sure we are comparing the same antibody (we must compare "apples to apples"). If talking about HepBs Ab both times, and it went from positive to negative in an uninfected and vaccinated person, then HepB booster vaccines may be given.

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Tg= (thyroglobulin) had tg panel 16.0 results, a tg antibody <0.9, a tg by lc-ms/ms, s/p (n/a)! result not dispersed in flowsheet. What does this mean?

Tg= (thyroglobulin) had tg panel 16.0 results, a tg antibody <0.9, a tg by lc-ms/ms, s/p (n/a)! result not dispersed in flowsheet. What does this mean?

While the: Normal range varies from lab to lab, your results are all normal. Why were they drawn in the first place. There are not as important as more conventional thyroid lab such as free T4 and tsh. Check w/your doctor.

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I tested negative for hiv with architect combo. But in the result it says only antibodies but not p24 ag. I thought it checks for ag/ab at Sametime. Is it possible to check only for ab with architect?

I tested negative for hiv with architect combo. But in the result it says only antibodies but not p24 ag. I thought it checks for ag/ab at Sametime. Is it possible to check only for ab with architect?

It tests for both: The Architect® combo test checks for bothHIV antibody and p24 antigen. If your result is reported as negative, it neither antibody nor antigen was detected. I suspect you have misinterpreted the wording of the test result. If in doubt, check with the doctor who ordered the test, or the laboratory where it was done.

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What kind of antibody tests are available to check for immunity to hep c?

What kind of antibody tests are available to check for immunity to hep c?

None: There is no such thing as immunity to hcv. Only hep a and b which can be determined by blood work.

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Does architecture HIV combo check for hiv2 group A and B antibodies?

Does architecture HIV combo check for hiv2 group A and B antibodies?

Yes it does: The ARCHITECT HIV Ag/Ab Combo assay is a chemiluminescent microparticle immunoassay (CMIA) for the simultaneous qualitative detection of HIV p24 antigen and antibodies to HIV type 1 (M and group O) and/or type 2 (HIV-2) in human serum and plasma. This assay does not distinguish between the detection of HIV-1 p24 antigen, HIV-1 antibody, or HIV-2 antibody...just a positive or negative result.