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Doctor insights on: What Is A Paraneoplastic Antibody Panel Supposed To Check For

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What is a paraneoplastic antibody panel supposed to check for?

What is a paraneoplastic antibody panel supposed to check for?

Autoantibody Panel: 1st off: this is an autoantibody panel through mayo medical labs. It is used for serological evaluation of patients who present with a subacute neurological disorder of undetermined etiology, especially those with known risk factors for cancer. ...Read more

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Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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All my paraneoplastic antibody panel came back negative. This is a good thing right?

Yes (?): Yes - they aren't positive. However that does not prove a paraneoplastic syndrome isn't occuring. The available antibody tests are not perfect. Also -- no - it doesn' clarify what the problem (that the test was performed to evaluate) is. ...Read more

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Does Paraneoplastic antibody syndrome blood test through Mayo Clinic is reliable enough?

Does Paraneoplastic antibody syndrome blood test through Mayo Clinic is reliable enough?

Yes: Mayo Clinic Lab is highly reliable, and is one of the best reference labs in the world. ...Read more

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Why would my dr be ordering a paraneoplastic ab panel if he's not looking for cancer. He's doing a bunch of blood work for possible autonomic dysfu?

Why would my dr be ordering a paraneoplastic  ab panel if he's not looking for cancer.  He's doing a bunch of blood work for possible autonomic  dysfu?

D/w your doctor: You should probably ask your doctor the reasons behind the order. Sometimes, the case are so complicated that possibilities of causes are in wide range and different testings are needed. Since i don't know exactly the case- pick up the phone and ask your doctor. Certain cancer sometimes is associated with different nonspecific symptoms in different body system-paraneoplastic lab is to check on it. ...Read more

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Is the test for paraneoplastic antibodies clinically useful?

Very much so: Some of the most puzzling clinical syndromes are caused by the immune response to tumors that may not be known to be present yet. There's a group of antibodies for which we can now test that will rule the known syndromes in this category in or out. It's not cheap and isn't to be ordered lightly, but it's a standard part of health care. ...Read more

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What are the Paraneoplastic antibodies blood tests? Why negative results can not rull out the syndrome?

Imperfect tests: Paraneoplastic syndromes are uncommon and the presence or absence of antibodies is only one evidence for making the diagnosis. See this site for more info. uncohttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299076 ...Read more

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If my paraneoplastic ab test came back positive does that mean I have an underlying cancer or will get cancer in the near future?

Paraneoplastic: Paraneoplastic syndrome is a disease or symptom that is the consequence of the presence of cancer in the body. So, if your panel is positive-depending on the sensitivity and the specificity of the panel- your doctor needs to make sure to look for presence of occult cancer in you. ...Read more

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I have either autoimmune pandysautonomia or paraneoplastic syndrome. My anti striational antibody was positive. I have metastatic thyroid ca. Which?

I have either autoimmune pandysautonomia or paraneoplastic syndrome. My anti striational antibody was positive. I have metastatic  thyroid ca. Which?

Complicated: Could be either, and to complicate matters dysautonomia can be cause by a paraneoplastic phenomenon. Either way the primary focus is to first treat the metastqatic thyroid ca and see how the dysautonomia progresses (and hopefully improves). ...Read more

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Why the antibodies test- paraneoplastic syndrome of mayo clinic and Aetna does not approved by the FDA?

Faulty policy: Many insurances consider certain antibody tests for paraneoplastic syndrome screening involving the nervous system experimental and investigational. They base this on various criteria including debt of research & FDA approval. The tests should be considered medically necessary when ordered selectively for evaluating persons with signs & symptoms of specific paraneoplastic syndromes. ...Read more