Doctor insights on:
What Is A Cure For Macular Amyloidosis
Amyloidosis macular: Need to see pictures. Several different treatments. Discuss with your Dr. Sometimes goes away but usually not. ...Read more
Is microdermabrasion is helpfull in macular amyloidosis as friction may make it worse. should i go for microdermabrasion?
Dermatologist: Macular amyloidosis is a condition without clear cause, and treatments are aimed at relieving symptoms of itchiness and improving cosmetic appearance. Dermabrasion has been used, but does not cure the problem, which may recur. The specific treatment best for you can be recommended by an experienced dermatologist. ...Read more
Hi..Can u tell me any home remedies to get rid of itching due to macular amyloidosis.....Its unbeatable even after taking anyihistamins...
Macular amyloidosis: Sedating antihistamines can be moderately effective.Topical and intralesional steroids may provide some relief if used with other treatments.Other treatments tried include topical dimethyl sulfoxide (dmso) and phototherapy (uvb) or puva).Surgical treatment to remove amyloid deposits includes laser vaporization, dermabrasion, and excision of individual lesions. However, in most cases lesions recur. ...Read more
Itching is unbearable coz of macular amyloidosis...Feel like to scratch with knife....Can u suggest any simple remedy or home remedy for the same plz.
Sorry, no simple rem: Sorry, but there are no simple remedies for a condition like macular amyloidosis (which I assume was confirmed by skin biopsy). You're right to avoid irritation. Also, Benadryl & similar medications can help with the itching. Beyond that, see a dermatologist for UV light therapy or laser therapy. Microdermabrasion won't work, will only make it worse. Lastly, steroid injections can be tried. GL! ...Read more
Kindly help me regarding cutaneous macular amyloidosis treatmnt .. Its spreading...Age 25 yrs ..Previous history of acne for many years?
The treatment is focused on relieving itch. Sedating antihistamines can be moderately effective. Topical and intralesional steroids may provide some relief if used with other treatments. Other treatments tried include topical dimethyl sulfoxide (dmso) and phototherapy (uvb) or puva).
Surgical treatment to remove amyloid deposits includes laser vaporization, dermabrasion, and excision. ...Read more
is there any risk of dementing process in cutaneus amyloidosis? The risk of having amyloud bodies in CNS? Im 49 with a 20 years hx of macular amyloidosis and now worried about dementia. Thanks
Not necessarily: We are comparing apples and oranges. The deposition of amyloid in the central nervous system involves cholesterol transporting systems, and the soluble amyloid may well be far more toxic. Furthermore, the greater issue is the effect of neurofibrillary tangles on the neuron, which may or may not be a downstream effect. So, do not worry, your risk is likely similar to those with no amyloid hx. ...Read more
Macular amyloidosis confirmed by skin biopsy from the pigmented patch on lower thigh. What is the line of treatment and prognosis .? Can it spread ?
Good prognosis: Macular amyloidosis is a local proliferation on the skin usually on the trunk as you have. It never spreads too much or into the blood. The treatment may be as simple as temovate (clobetasol) ointment twice daily to local cortisone injections, local liquid nitrogen, dermabrasion or laser treatment. ...Read more
I am 35.My doctor diagnosed my problem as cutaneous amyloidosis macular.It has spread across my neck, face, ears, back, legs.What is the besttcure?
No: I wish it were possible.Get a more detailed answer ›
No: It cannot be cured but they are meds that can be extremely effective in controlling the disease. ...Read more
No: Ed only improves the appearance. But it also creats new sacrs. Ed is not the answer. ...Read more
Cryoglobunliemia: May have no symptoms if cryo levels are low. Cryos can accumulate in the tissues, especially blood vessels. Excess bruising (purpura) on the skin is seen and sometimes a vasculitis (inflammation of the small blood vessels) - especially the lower extremities. Occassionally with very cold weather the fingers may get dark due to sludging. This could even cause damage of the finger tips. So keep warm! ...Read more
No, but just as: Serious. Amyloidosis is accumulation of an abnormal protein in various tissues. It also occurs in some cancers, e.g., multiple myeloma, a bone cancer. It affects the function of involved organs, e.g., liver, heart, kidney, etc. Amyloid also plays a role in the pathogenesis of Alzheimer's dementia. ...Read more
No blood test:
There is no blood test to detect amyloidosis. Sophisticated laboratory techniques called electrophoresis or free light chain assays may reveal early evidence of some amyloid proteins.
A biopsy is needed to confirm a diagnosis of amyloidosis and determine the specific type of protein involved in the disease. ...Read more
No: Amyloidosis is diagnosed by tissue biopsy such as a rectal biopsy wherein the amyloid in the tissue is detected by the congo red stain. It is the accumulation of particular misfolded proteins in the space between cells (extracellular matrix) that distinguishes amyloidosis. There are many types of amyloid proteins than can cause amyloidosis. ...Read more
It can stabilize:
The extent of involvement by amyloidosis is important.. The heart, kidneys, pituitary....Bone marrow...
Mild involvements could go on for years...Without progression or medications..
For severe... It could deteriorate..Medications could prolong life...
Ask your doctor and hematologist to go to a referral center. ...Read more
Itchy papules: Τhis is the most common form of primary localised cutaneous amyloidosis. It presents as an intensely itchy rash on the shins, thighs, feet, and forearms. Lesions consist of multiple raised spots (papules) that are scaly and red/brown in color. More common in people of chinese descent and in males 50-60 yrs of age. It may be associated with multiple endocrine disorders. ...Read more
Specific test?: First: clinical. Second:confirmation and detection of monoclonal gammopathy on serum protein electrophoresis, with microscopic examination of abdominal fat, rectal or gingival biopsies looking for amyloid protein ...Read more