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Doctor insights on: What Infections Cause High Ig E Levels

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In the absence of overt allergic symptoms, does a high IgE level (600; normal 0-100) indicate a protozoal infection like trichomoniasis or babesiosis?

In the absence of overt allergic symptoms, does a high IgE level (600; normal 0-100) indicate a protozoal infection like trichomoniasis or babesiosis?

Usually not: First of all, the old biology-class story that "IgE fights parasites" isn't true; it's mostly about worms, not the protozoa you mention. Usually we never find the cause for a high IgE, though some folks with bad allergies run high levels and there are a handful of uncommon diseases where they run high. Best wishes. ...Read more

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Dr. Brad Goldenberg
9 doctors shared insights

Infection (Definition)

Infections are invasions of some other organism (fungus, bacteria, parasite) or viruses into places where they do not belong. For instance, we have normal gut bacteria that live within us without causing problems; however, when those penetrate the bowel wall and enter the bloodstream, ...Read more


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Does an IgE level of 582 (normal 0-100) indicate chronic protozoal infection (or some other infection)? If not, what does it indicate? On electrophoresis I was free of m-spikes, but don't know if that looked at IgE, so is IgE myeloma possible too?

Does an IgE level of 582 (normal 0-100) indicate chronic protozoal infection (or some other infection)?  If not, what does it indicate?  On electrophoresis I was free of m-spikes, but don't know if that looked at IgE, so is IgE myeloma possible too?

No: Allergic diseases , especially eczema, are more likely to be associated with an elevated IgE level. Do you have symptoms which prompted the IgE measurement? As far as IgE myeloma, it is very rare condition and the level is not high enough for making this diagnosis. If you have no symptoms otherwise, I would just monitor your progress. ...Read more

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What could cause high IgE levels?

What could cause high IgE levels?

Genetics: The tendency to make more ige in response to foreign substances that enter the body (aka allergens) is inherited. Allergies and parastic infections are the common reasons why people develop high ige levels. There are some rare disorders associated with increased risk of infections associated with very high levels of ige. A board-certified allergist can help sort this out for you. ...Read more

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What causes high IgE levels in blood?

What causes high IgE levels in blood?

Allergy, Parasites: Unless you have an immunoglobulinopathy, it is usually caused by hypersensitivity to a substance (allergy) or parasitic infection (e.g. Worms). ...Read more

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My son (4) had an IgE level of 1400 (high) what could cause this? He does have eczema and had a few environmental and good allergies.

My son (4) had an IgE level of 1400 (high) what could cause this? He does have eczema and had a few environmental and good allergies.

Consider testing: The ige level that was measured is considered to be extremely high. If your son has pulmonary symptoms, a chest radiograph may be ordered by your physician to document structural changes in the airways. There is a condition called abpa which afffects about 10% of asthmatics and CF patients. Airway fungal sensitization can be measured and tests ordered to detect reactions to fungi as well. ...Read more

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What causes elevated mpv, lymphocytes, eosinophils, and IgE levels?

What causes elevated mpv, lymphocytes, eosinophils, and IgE levels?

WBCs elevated,ige: This senario of elevated eosinophils, lymphocytes and total ige, will most probabely a person has allergic disorder and a viral infection. ...Read more

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I have bad allergies and a high IgE level (1300). Will this wear my immune system out over time? Also can allergies cause body aches and fatigue?

I have bad allergies and a high IgE level (1300). Will this wear my immune system out over time? Also can allergies cause body aches and fatigue?

Maybe: Allergy is from a skewed immune reaction to otherwise innocuous substances- usually a protein. People with allergic asthma are more susceptible to respiratory infections for this reason. Allergy does not usually cause body aches although sleep disruption from your allergic conditions may cause body aches and fatigue. Uncontrolled asthma can cause fatigue. See an allergist. ...Read more

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My son's iGe levels are high. we do allergen shots twice a week for 6 months now. what else could cause constant ear draining and high iGe levels?

My son's iGe levels are high. we do allergen shots twice a week for 6 months now. what else could cause constant ear draining and high iGe levels?

Usually allergy: In your son's case, the elevated IgE level is likely related to his allergic diseases. However there are also less common causes for elevated IgE level . Since 20% of the people don't respond to allergy shots and it may take up to a year to experience benefits from them, you need to talk to your allergist re. medication required to control his nasal congestion and ear issues. ...Read more

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Can celiac disease cause elevated WBC levels (above 20, 000) and fever ? Is a person wid high IgE level is more prone to celiac as well?

Can celiac disease cause elevated WBC levels (above 20, 000) and fever ? Is a person wid high IgE level is more prone to celiac as well?

No and No: The elevated WBC calls for a serious workup by your physician -- we don't want to miss endocarditis, leukemia or any of several other troublesome, possibly treatable diseases. The ige system is barely related to the pathogensis of celiac sprue and the assay is worthless to screen for it. I'm glad you're being proactive & hope you'll get straight talk from your physician now. ...Read more

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I m 25y student. Can you tell me steroids are safe for life time.... I take deflazcort 30mg daily in the morning due tuo high IgE level.. ?

I m 25y student. Can you tell me steroids are safe for life time.... I take deflazcort 30mg daily in the morning due tuo high IgE level.. ?

Depends on need: Long term steroid treatment has adverse implications. You and your doctor need to determine the need for taking steroids and balance the need for treatment vs the side effects of steroids, . ...Read more

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If my IgE level is high what am I suffering?

If my IgE level is high what am I suffering?

Allergies: High ige levels are generally a marker for allergic potential. Therefore, the higher your ige, the more likely you are to have allergic diseases such as hayfever, asthma, or eczema. ...Read more

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I went to an allergist and he told me that my IgE level was 1280. He said that was high. But how high is that? Or is it high for normal?

I went to an allergist and he told me that my IgE level was 1280. He said that was high. But how high is that? Or is it high for normal?

IgE level: A normal ige is usually pretty low. The exact normal given by each lab varies but the upper limit of the normal range is usually not much over 100. A level of 1280 is certainly high, but much higher levels than that are sometimes seen, as well. Very high levels can occur with significant allergies, eczema, parasitic infestations and a few rare diseases. It's good you have an allergist! ...Read more

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High IgE levels related to cancer?

High IgE levels related to cancer?

No: Allergy, job's, if moderate just your personal physiology. ...Read more

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My sons IgE level has been high for 3 years the highest it's been was 30, 000 which they found toxocara but its still 3, 100 is that a concern.

My sons IgE level has been high for 3 years the highest it's been was 30, 000 which they found toxocara but its still 3, 100 is that a concern.

High IgE: It can be from a persistent parasitic infection or other causes, but 3000 is still high, you need to follow up with his infectious disease specialist. ...Read more

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Is a constant IgE level of 200+ iu/ml something that could potentially cause severe symptoms that i have, or is it something that should be neglected?

Is a constant IgE level of 200+ iu/ml something that could potentially cause severe symptoms that i have, or is it something that should be neglected?

Elevated IgE: An elevated ige level can be seen in many disorders including allergic disorders (eczema, asthma), inflammatory disorders and even in some immune deficiency disorders. The level by itself doesn't mean as much, but it alerts the physician to assess for an underlying cause. ...Read more

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Facial spasm and high IgE level is neurological?

Facial spasm and high IgE level is neurological?

Spasm yes, IgE no: A facial spasm can be a neurological symptom. There is a condition called hemifacial spasm for example, which is a paroxysmal activation of the muscles affecting smiling and eye closure on one side. I am not aware that high IgE levels correlate with this, or any other, neurological condition. ...Read more