Doctor insights on:
What Infections Cause High Ig E Levels
In the absence of overt allergic symptoms, does a high IgE level (600; normal 0-100) indicate a protozoal infection like trichomoniasis or babesiosis?
Usually not: First of all, the old biology-class story that "IgE fights parasites" isn't true; it's mostly about worms, not the protozoa you mention. Usually we never find the cause for a high IgE, though some folks with bad allergies run high levels and there are a handful of uncommon diseases where they run high. Best wishes. ...Read more
Infections are invasions of some other organism (fungus, bacteria, parasite) or viruses into places where they do not belong. For instance, we have normal gut bacteria that live within us without causing problems; however, when those penetrate the bowel wall and enter the bloodstream, ...Read more
Does an IgE level of 582 (normal 0-100) indicate chronic protozoal infection (or some other infection)? If not, what does it indicate? On electrophoresis I was free of m-spikes, but don't know if that looked at IgE, so is IgE myeloma possible too?
No: Allergic diseases, especially eczema, are more likely to be associated with an elevated IgE level. Do you have symptoms which prompted the IgE measurement? As far as IgE myeloma, it is very rare condition and the level is not high enough for making this diagnosis. If you have no symptoms otherwise, I would just monitor your progress. ...Read more
Genetics: The tendency to make more ige in response to foreign substances that enter the body (aka allergens) is inherited. Allergies and parastic infections are the common reasons why people develop high ige levels. There are some rare disorders associated with increased risk of infections associated with very high levels of ige. A board-certified allergist can help sort this out for you. ...Read more
My son (4) had an IgE level of 1400 (high) what could cause this? He does have eczema and had a few environmental and good allergies.
The ige level that was measured is considered to be extremely high. If your son has pulmonary symptoms, a chest radiograph may be ordered by your physician to document structural changes in the airways.
There is a condition called abpa which afffects about 10% of asthmatics and CF patients. Airway fungal sensitization can be measured and tests ordered to detect reactions to fungi as well. ...Read more
WBCs elevated, ige: This senario of elevated eosinophils, lymphocytes and total ige, will most probabely a person has allergic disorder and a viral infection. ...Read more
I have bad allergies and a high IgE level (1300). Will this wear my immune system out over time? Also can allergies cause body aches and fatigue?
Maybe: Allergy is from a skewed immune reaction to otherwise innocuous substances- usually a protein. People with allergic asthma are more susceptible to respiratory infections for this reason. Allergy does not usually cause body aches although sleep disruption from your allergic conditions may cause body aches and fatigue. Uncontrolled asthma can cause fatigue. See an allergist. ...Read more
My son's iGe levels are high. We do allergen shots twice a week for 6 months now. What else could cause constant ear draining and high iGe levels?
Usually allergy: In your son's case, the elevated IgE level is likely related to his allergic diseases. However there are also less common causes for elevated IgE level. Since 20% of the people don't respond to allergy shots and it may take up to a year to experience benefits from them, you need to talk to your allergist re. Medication required to control his nasal congestion and ear issues. ...Read more
Can celiac disease cause elevated WBC levels (above 20, 000) and fever? Is a person wid high IgE level is more prone to celiac as well?
No and No: The elevated WBC calls for a serious workup by your physician -- we don't want to miss endocarditis, leukemia or any of several other troublesome, possibly treatable diseases. The ige system is barely related to the pathogensis of celiac sprue and the assay is worthless to screen for it. I'm glad you're being proactive & hope you'll get straight talk from your physician now. ...Read more
I m 25y student. Can you tell me steroids are safe for life time.... I take deflazcort 30mg daily in the morning due tuo high IgE level.?
I went to an allergist and he told me that my IgE level was 1280. He said that was high. But how high is that? Or is it high for normal?
IgE level: A normal ige is usually pretty low. The exact normal given by each lab varies but the upper limit of the normal range is usually not much over 100. A level of 1280 is certainly high, but much higher levels than that are sometimes seen, as well. Very high levels can occur with significant allergies, eczema, parasitic infestations and a few rare diseases. It's good you have an allergist! ...Read more
My sons IgE level has been high for 3 years the highest it's been was 30, 000 which they found toxocara but its still 3, 100 is that a concern.
No: Donating blood will not lower IgE levels. ...Read more
Is a constant IgE level of 200+ iu/ml something that could potentially cause severe symptoms that I have, or is it something that should be neglected?
Spasm yes, IgE no:
A facial spasm can be a neurological symptom. There is a condition called hemifacial spasm for example, which is a paroxysmal activation of the muscles affecting smiling and eye closure on one side.
I am not aware that high IgE levels correlate with this, or any other, neurological condition. ...Read more
Usually not: High ige is usually a sign of allergy not malignancy. ...Read more
Eczema, asthma, etc.: In clinical practice allergic rhinitis, eczema and asthma are the most common reasons for elevated ige. Parasitic infections can cause an increase in ige, and it can also be elevated in certain immune deficiencies, such as hyper-ige syndrome. Allergic bronchopulmonary aspergillosis is a rare cause. ...Read more
There are five types of antibodies in the blood. The other word for antibody is immunoglobulin, or ig.
The five types of antibody are g (keeps you immune), a (protects your surfaces such as nose and gut from infection), m (kills currently active infections), d (unknown function), and e (worm infections and allergies.
So the e type is ige and when it is up think of allergies or worms. ...Read more
Elevated IgE level: Ask your doctor for a referral to an allergist/immunologist for evaluation. Incidental finding of high IgE without any symptom is not uncommon, several causes for such findings, most common is having allergies, parasitic infection or rarely a blood disease. Better be seen by a specialist for further management and follow up, and no need to be concerned. Check aaaai. Org 4 an allergist in your area ...Read more
My IgE level is 1300 and my sister has elevated IgM and IgA levels. Is this genetic? And could my other levels be off too?
Immunoglobulins: A high ige is seen in allergies and allergic asthma and eczema. This is what your level means. Your sister's is a different problem, slight elevations in both igm and IgA can be reactions to acute infections, she is best evaluated by an immunologist to determine if this needs to be investigated further. ...Read more
I am 43 years female and ihave high IgE level (850) associated with stomach apcet headach and rash?
Please rephrase: I'm not sure exactly what you're asking about...Can you rephrase the question? An elevated ige level is almost always associated with atopy (the state of being allergic), and is quite common in people with seasonal allergies, food allergies, and especially allergic eczema. ...Read more
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