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What Immune Cells Induce Apoptosis
Immune cells are the white blood cells (WBC) in the blood. There are different types of wbcs that fight infections or respond to immunizations in different ways. . For example, your immune response to the 1st measles vaccine differes from the second vaccination in the types of immune cells that react to the vaccines. Immune cells also go out of whack, and ...Read more
Many factors.: There are many factors/regulators that induce apoptosis in cancer and normal cells. These are defective or turned off in cancer cells. For example, the x-linked inhibitor of apoptosis protein (xiap) is overexpressed in cancer cells. Xiaps bind to caspase-9, and suppress apoptotic activator cytochrom c, allowing the damaged cells to live. Deactivation of p53 apoptotic protein is another example. ...Read moreSee 1 more doctor answer
Possibly many ways.: This is the active ingredient in chili peppers that causes a burning sensation. It binds to the vanilloid receptor subtype 1 (vr1), which triggers a temperature oriented inflammatory reaction. Some of its effects on cancer are inconclusive, like stomach cancer. It appears to have proposed effects of other cancers, like breast cancer by causing apoptosis by affecting the egfr/her-2 pathway. ...Read moreSee 1 more doctor answer
In general: Neutrophils are mobilized to combat bacterial processes and to help with tissue repair. By contrast, lymphocytes are important in viral processes and determination of self/ not self ie organ transplant rejection and other " invaders ". ...Read more
Lymphocyte family: These are a special group of white blood cells that actually kill cells that the body perceives to perhaps be infected. This is usually, but not always, a good thing. We pathologists recognize them as cd8+, staining brown with a special stain. I'm glad you're interested in the immune system, which still amazes scientists. Thanks for asking. ...Read more
Yes and no: There is often some immune response to cancers. We pathologists can often see it under the microscope. Almost all cancers evade it eventually. Immune enhancers are highly effective for a minority of melanomas and kidney cancers. The immune response, especially to oat cell carcinoma, can make a person horrendously sick (blind, insane, more). Ignore any 'pop' immune enhancers for cancer. ...Read moreSee 3 more doctor answers
They are immortalize: Programmed cell death is markedly reduced in cancer due to a phenomenon related to prolongation of chromosomal integrity. Normal cell that divide have caps on the top on the tops of their chromosomes known as telomeres. With each division, the telomere is reduced until the cell can not divide any further. Cancer has an enzyme known as telomerase that constantly replace the telomeres. ...Read more
Nk cells have enzymes that attack foreign, virus infected, or cancerous cells? Is that how they work?
NK cells: Yes, natural killer cells are part of the innate immune system. Unlike other immune cells, they do not have to have prior exposure to an invader in order to attack it. They do release enzymes which essentially poke holes into the cell they are trying to destroy. They release their enzyimes into these holes. The enzymes travel to the center of the cell and cause it to explode, known as apoptosis. ...Read more
No. It is a: Characteristic of some cancers, lymphoma and small cell lung cancer, to forget how to apoptose, and treating them causes the tumor to dissolve reducing bulk. But it is usually only a characteristic and not the cause of the cancer: a sign that there is a cancer, and it is molecularly controlled, but there are other things also wrong. ...Read moreSee 1 more doctor answer
When testing the immune system can bloods test. B cells t cells nk killer cells, what is the best way to test immune function in depth?
Good start: Yes, the parameters you mentioned can be tested easily, and there are numerous other tests which may help to assess "immune function" which can be utilized depending upon the clinical situation and indices of suspicion. You might see either an infectious diseases expert or an immunologist. Good luck. ...Read moreSee 1 more doctor answer
Mutations: Several of the known mutations that contribute to the malignant phenotype work by opposing the normal mechanisms of apoptosis. The discovery of bcl2 mutations driving lymphoma was the first of many. Here's a now-classic paper http://carcin.Oxfordjournals.Org/content/21/3/485.Full. ...Read more
B-cells: The ways in which HIV and hiv-infected immune cells cause overgrowth of uninfected b-cells, making them divide (polyclonal) and overfunction (polyclonal gammopathy, b-cell quasi-lymphomas) are coming to be known and are hugely complex. Best recent review http://www.Nature.Com/nri/journal/v9/n4/execsumm/nri2524.Html. ...Read more
If cells such as T cells and NK killer cells ATTACK organs or neurons but don't produce Antibodies what methods are used to diagnose this ?
Clinical diagnosis: Clinical diagnosis by an appropriately trained rheumtologist ...Read more
If EBV virus invaded specific cells or neurons could this cause a severe autoimmune response to mistakenly attack those cells or neurons?
Correct assessment: Ebstein-barr virus is associated with infectious mononucleosis, can be associated with the acute immune polyneuritis, guillain-barre syndrome, and appears associated with adult ms in over 99% of all cases. So, clearly, can influence immune disorders both in peripheral and central nervous systems. ...Read moreSee 1 more doctor answer
Does white blood cells digest or alter the endotoxins released by bacteria lysis during phagocytosis?
Yes: to a degree. not an all-or-none phenomenon. Free endotoxin that is in the extracellular environment does not necessarily trigger phagocytosis by itself. Toll-like receptors on the white cells will bind to it and these receptors typically become part of phagosomes upon entry. ...Read more
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