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Doctor insights on: What If Your Liver Is Producing Too Much Alkaline Phosphatase

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What if your liver is producing too much alkaline phosphatase?

What if your liver is producing too much alkaline phosphatase?

It doesn't: Liver does not produce alkaline phosphatase. Instead it is elevated in conditions where inflammation / injury to te liver or bike ducts are occurring. ...Read more

Dr. Julie Abbott
2 Doctors shared insights

Liver (Definition)

This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more


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What are the signs the your liver is producing too much alkaline phosphatase?

What are the signs the your liver is producing too much alkaline phosphatase?

There are none.: An elevated alkaline phosphatase is a blood test lab finding. If elevated, could be liver, gall bladder or bone problem. If there is only a mild elevation with all other blood tests being normal, it is possible that there is no problem, and just follow up with repeat blood testing. As usual, don't self- or internet-diagnose. Every american needs a good pcp/team to turn to. (my mantra). ...Read more

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How do I lower my alkaline phosphatase levels in my liver?

How do I lower my alkaline phosphatase levels in my liver?

Depends on the: Cause. Why is your alkaline phosphatase elevated? Do you know that it is due to liver disese? Bone disese also elevates alkaline phosphatase. It would be prudent to consut your doctor. This is not an issue for self treatment. ...Read more

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Should I be concerned if my liver enzymes go from 107 to 159? The alkaline phosphatase

Maybe: Normal is up to 140 so 159 is not very elevated. Liver function tests usually do not get dr's concern until 5-10 times normal but depends on your health and medications and if you drink or use drugs or smoke etc, etc. ...Read more

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Can you tell me what alkaline phosphatase level in the liver mean?

Can you tell me what alkaline phosphatase level in the liver mean?

If high...: It's a marker for slow or obstructed bile flow somewhere in the liver. It's also up in later pregnancy, any situation with growing or healing bone, and in many folks simply from a nonfasting specimen. ...Read more

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My Alkaline Phosphatase is 139, all other liver test normal. I am currently on Zejula and super anemic.

My Alkaline Phosphatase is 139, all other liver test normal. I am currently on Zejula and super anemic.

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, alkaline phosphatase of 139 alone is not a cause for concern. I trust that you are under the care of a doctor for the treatment of anemia.
Wish you good health!
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex, if you have sex. ...Read more

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Test came back 199ran test on alkaline phosphatase said high in intestine an liver please let know more in intestine?

Test came back 199ran test on alkaline phosphatase said high in intestine an liver please let know more in intestine?

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, alkaline phsophatase is made in the liver, intestine, bone and placenta. It would be prudent to see your doctor to ascertain the cause of elevated enzyme. ...Read more

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In 2008 - alkaline phosphatase level 166 and liver size 180mm. In 2016 my liver was 157mm, no alkaline phosphatase tested. Just has tests again - alk phos 121, liver size 210mm. Why alk phos lower but liver larger? How Can I shrink it? How long to?

In 2008 - alkaline phosphatase level 166 and liver size 180mm. In 2016 my liver was 157mm, no alkaline phosphatase tested. Just has tests again - alk phos 121, liver size 210mm. Why alk phos lower but liver larger? How Can I shrink it? How long to?

Need more info: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, one reason for your liver to be larger could be fatty infiltration. If you are overweight, lose weight. If you are diabetic, better control of diabetes is important. Do not drink alcohol at all. Have your medications checked by your doctor ...Read more

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What role does alkaline phosphatase play in liver function tests?

Non specific: It is 1of the tests done 4 liver function. Also present in kidneys placenta and bone. So as a stand alone test it is not real helpful. In combination with other tests it can b more specific 4 the liver. As a stand alone it could b related 2 bone tumor, paget's disease of bone or renal disease. If elevated and the liver=cause. Hepatitis bile duct obstruction drug toxicity as tylenol (acetaminophen) or etoh abuse. ...Read more

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I am having low and high alkaline phosphatase result. Ultrasound and X-ray report shows a healthy liver. What could be the cause?

Many sources: Alkaline phosphate is high due to multiple reasons. They get high due to problem in liver, bone or intestine. It's unclear if your level gets to normal. It will be wise to discuss with pcp. ...Read more

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Could having a blood test only two days after a cellulitis flare up cause my liver levels, as well as my alkaline phosphatase to go up?

Could having a blood test only two days after a cellulitis flare up cause my liver levels, as well as my alkaline phosphatase to go up?

Possibly: Any infection, like a cellulitis can cause a systemic response leading to inflammation of other organs including your liver. Medications you are taking such as antibiotics, can also cause elevated liver enzymes and an elevated alk phosphatase level ...Read more

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I m 18 yrs old male and recently I had tested my blood sample and Liver Function Test was carried. Alkaline phosphatase result is 156 U/L and other r?

I m 18 yrs old male and recently I had tested my blood sample and Liver Function Test was carried. Alkaline phosphatase result is 156 U/L and other r?

Likely normal: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, if your bones are still growing, it is likely a normal level. You may consult this site for more info on this topic.

https://www. Nlm. Nih. Gov/medlineplus/ency/article/003470.htm ...Read more

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Chronic elevated alkaline phosphatase. GGT normal, other blood test negative. Liver ultrasound clear. My doctors said it is a mystery of elevated AP.

Chronic elevated alkaline phosphatase. GGT normal, other blood test negative. Liver ultrasound clear. My doctors said it is a mystery of elevated AP.

Not necessarily live: Alk. Phos. Can be elevated in liver disease, but the enzyme is found in other organs, including bone, biliary tract (gall bladder), intestine and, interesting, the placenta! Certain medications can also cause an elevation.At the very least, a gallbladder ultrasound, a measurement of parathyroid hormone, calcium & phosphate levels and a review of your meds should be done. ...Read more

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I did a liver profile test : alkaline phosphatase 47.1 u/l aspartate aminotransferase (sgot)39 u/l alanine transaminase (sgpt)53.7 u/l?

I did a liver profile test : alkaline phosphatase 47.1 u/l aspartate aminotransferase (sgot)39 u/l alanine transaminase (sgpt)53.7 u/l?

Get a follow-up: Expect these to be repeated iwth you off alcohol and any meds you don't truly need. There may be a hepatitis, iron overload, wilson's ; maybe autoimmue hepatitis workup in your future. You also list B12 ; vitamin d deficiency; I trust these are being managed ; the causes identified. ...Read more

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My liver function tests results bilirubin total-4.35 sgot- 468 sgpt- 908 ggt- 132 alkaline phosphatase-175.8 anything serious, could this be jaundice?

My liver function tests results bilirubin total-4.35 sgot- 468 sgpt- 908 ggt- 132 alkaline phosphatase-175.8 anything serious, could this be jaundice?

See details: These results suggest significant liver disease and this must be evaluated immediately. Speak with the doctor who ordered the tests. Get screened for hepatitis and consider a referral to a GI specialist. ...Read more

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Yellow stools, sometimes loose/watery. Bilirubin in range, amylase & lipase normal and alkaline phosphatase in range. Ultrasound shows normal g/bladder and main ducts. Liver normal. No jaundice, ?

Yellow stools, sometimes loose/watery. Bilirubin in range, amylase & lipase normal and alkaline phosphatase in range. Ultrasound shows normal g/bladder and main ducts. Liver normal. No jaundice, ?

It seems you had: Extensive work up. If no weight loss and stool analysis is negative for malabsorption, irritable bowl could be considered. Feet swelling could be due multiple reasons including adverse effect of Norvasc, (amlodipine) vascular insufficiency, CHF or dependent ...Read more

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38 year old female fatigued, bloating, gas. Hx of fluctuating liver enzymes for almost 3 years. Gallbladder removed 1.5 years ago. ALT 61, Alkaline Phosphatase 154, globulin 3.9.Hep, ANA, lupus, rheumatoid all negative. Please help. Other suggestions?

38 year old female fatigued, bloating, gas. Hx of fluctuating liver enzymes for almost 3 years. Gallbladder removed 1.5 years ago. ALT 61, Alkaline Phosphatase 154, globulin 3.9.Hep, ANA, lupus, rheumatoid all negative. Please help. Other suggestions?

Possible celiac: Celiac disease remains a possibility with reported symptoms and liver function test abnormalities. An evaluation with a liver specialist may be needed for reviewing additional history and consideration for tests to rule out disorders of biliary tree, pancreas, and chronic liver diseases. ...Read more

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I'v long standing colitis. Done LFT. My bili is bit high. SGPT/Alkaline Phosphatase/GGT/ Pancreas-OK. SGOT bit high. Ultrasound - all OK but mild fatty liver. Lipid Prof & CBC-OK. No abd pain. Was 218lbs. Started home diet & lost 16 lbs in 4m.Is it PSC?

I'v long standing colitis. Done LFT. My bili is bit high. SGPT/Alkaline Phosphatase/GGT/ Pancreas-OK. SGOT bit high. Ultrasound - all OK but mild fatty liver. Lipid Prof & CBC-OK. No abd pain. Was 218lbs. Started home diet & lost 16 lbs in 4m.Is it PSC?

Continue the wt loss: Not sure what is PSC, but your obesity (I'm assuming obesity by your weight, but I don't have your height for confirmation) can cause your fatty liver which can cause your LFT abnormalities. Work with your primary clinician on your weight loss while continuing to monitor your LFTs. Hope that helps ...Read more

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How should I lower my alkaline phosphatase?

Elevated Alk Phos: Question would be why is your alkaline phosphatase elevated? ? If the levels are abnormal, there is usually a reason. Treating the symptoms without understanding why you have an elevated level is counter-productive. You should see your primary care physicians and have labs re-checked. If it's persistently high, then there should be referral to a rheumatologist or orthopedic surgeon. ...Read more

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Medicine for high alkaline phosphatase levels?

Wrong approach: Alkaline phosphatase is a lab value to tell a physician what is happening, not a medical problem to treat. It can be high just because you're growing (teens tend to be maybe 5x the upper limit of the reference range). About 5% of older folks have a high alk phos for "no reason", presumably paget's of the bone that never becomes evident; nonfasting samples may have it from the intestine. ...Read more

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Alkaline phosphatase elevated should I be concerned?

Depends: This depends on how elevated the levels are and whether you have any associated conditions (for example, pregnancy) which are known to cause elevated levels. Talk to your doctor for more information. ...Read more

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What is considered a high alkaline phosphatase value?

Above 140IU/L: The normal range is 20 to 140 iu/l in adult. ...Read more

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What are the causes for elevated alkaline phosphatase?

Liver bone & GB: Liver disease, bone disease and gallbladder are most common. However an elevated alk phos does not absolutely mean there is a true disease present. ...Read more

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Need help. Is 150 u/l alkaline phosphatase really high?

It depends: Alkaline phosphatase comes from different sources and depending on the site of the lesion, it may be really high. Please note that all lab results need to be interpreted in the clinical context and the doctor who ordered the test is usually in the best position to do that. ...Read more

Dr. Andrew Seibert
666 Doctors shared insights

Alkaline Phosphatase (Definition)

The normal range is 20 to 140 iu/l.[12] high levels can indicate active bone formation occurring as alp is a byproduct of osteoblast activity (such as the case in paget's disease of bone). Levels are also elevated in people with untreated celiac ...Read more