Doctor insights on:
What Happens When You Stop Taking Tamoxifen
Nothing: Simply resume your regular dosing and tell your doctor who prescribed it. ...Read more
This medication is used to: treat breast cancer that has spread to other parts of the body in men and women. Treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy. Reduce the risk of developing a more serious type of breast cancer in women who have had ductal carcinoma in situ (dcis; a type of breast cancer ...Read more
1 week: 1 week should be enough time.Get a more detailed answer ›
Not that many:
Let us start with the paradox that stopping seems to work as a cancer therapy?!?
http://www. Ncbi. Nlm. Nih. Gov/pmc/articles/PMC3180409/? report=classic
Then, not blocking female hormones whoe allow these hormones to begin working. Menstrual cycling possibly returning, breast growth pssible (not likely) mood changes. ...Read more
My wife is 4 weeks pregnant should I stop using tamoxifen for slight gyno and is it going to effect the baby.
Does copaxone (glatiramer) effect the way tamoxifen works, on tamoxifen since 2010, menstrual cycle stop, started copaxone (glatiramer) in october 13' cycle came 2 weeks after?
Having a TLH/BSO but on tamoxifen. I know I stop the tamoxifen prior to surgery, how soon? Surgeon says ask onc onc says ask surgeon. Do I stop Lipitor (atorvastatin)?
Stop both 1wk preop: I assume that the rationale for tamoxifen and the hyst BSO are for metastatic breast Ca. If the oophorectomy controls the disease the tamoxifen should not be used in order to evaluate the effect of castration on disease. Lipitor (atorvastatin) can ne restarted when post op diet is resumed. Hormone ablation best used for ER+ disease and not triple neg problems. ...Read more
Yes: Tamoxifen is an antiestrogen that blocks the ability of breast cancer cells to use estrogen; therefore, it is only effective in hormone sensitive (estrogen receptor +) breast cancers. When taken for 5 years, tamoxifen has been shown to both stop the growth of cancer cells in breast cancer patients and to prevent the development of breast cancer in women that are at high risk. ...Read more
Yes.: Women with a history of ductal-carcinoma-in-situ (dcis) may have a 50% reduction in developing a second breast cancer when taking tamoxifen for 5 years ("chemoprevention"). Furthermore, following a lumpectomy, the combination of tamoxifen and radiation therapy may have a decreased risk of cancer recurrence in the affected breast greater than either therapy alone. ...Read more
Side effects?: The most experienced side effects of all hormonal therapy are menopausal symptoms (ie.Hot flashes, etc). There is a small increased risk of blood clots similar to hormone replacement therapy, in women with an intact uterus, there can be irreg bleeding and thickening of the uterine wall. If ignored this can rarely progress to uterine cancer that can be cured with a hysterectomy. ...Read more
Yes: Tamoxifen interferes with estrogen action causing hot flashes. Taking estrogen to control hot flashes would defeat the primary reason to take tamoxifen so that is not an option. Some women with hot flashes are helped by taking some antidepressants (ssri). Another option is to try clonidine, a blood pressure medication. Non of these are 100% effective, but some women definitely benefit from them. ...Read more
Aim for better adher: An occasional missed dose is not a big deal and would not compromise the efficacy of tamoxifen. But better adherence should be executed. One way to do this is to make it a habit to take your medicine same time everyday: it could be timed as the first thing or the last thing you do daily. Then it will become a habit. ...Read more
Blocks estrogen: Some breast cancer cells have receptors on them that bind to estrogen in order to grow. Tamoxifen acts as an "antagonist" and blocks estrogen from binding to these receptors on the cancer cells by binding to them first. With tamoxifen sitting in estrogen's place, the cancer cell can no longer grow. ...Read more
Once per day:
Tamoxifen is most commonly used to treat breast cancer. The dose is (usually) 20mg per day and taken for 5 years. This medication is also used for people considered "high risk" for breast cancer to help decrease their risk of developing it in the future.
I recommend you speak with your oncologist about specific recommendations for your case. ...Read more
Blocks ER: Tam binds and blocks signals to the estrogen receptor present in er+ breast cancer. While this has benefits in cancer treatment it produces side effects - menopausal symptoms, possible uterine wall thickening & even malignancy if ignored, & increased risk of blood clots (similar to hormone replacement). In most cases of ca the benefits far outway the risks but must be weighed in risk reduction. ...Read more
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