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Doctor insights on: What Happens When Estrogen Levels Are High

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Dr. Stanley Swaby
Board Certified, Obstetrics and Gynecology
20 years in practice
367K people helped
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1
I'm a female in my mid 20s, what are symptoms of high estrogen levels? Are high levels bad?

I'm a female in my mid 20s, what are symptoms of high estrogen levels? Are high levels bad?

It varies: Very high estrogen levels may be a sign of ovarian or adrenal tumor. In general estrogen levels vary with the menstrual cycle. Too much estrogen may cause symptoms such as breast tenderness, weight gain, bloating, water retention, irregular uterine bleeding, headaches/migraines, abnormality of the uterus (hyperplasia) which can lead cancer. Some literature suggests anxiety and depression, etc ...Read more

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Dr. Christopher Crosby
Board Certified
10 years in practice
92K people helped
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Estrogen (Definition)

Estrogen is a hormone that is secreted by the ovaries and affects ovulation, ...Read more


Dr. Mark Trolice
Board Certified, Fertility Medicine
25 years in practice
128K people helped
2

2
What happens if you have too high of an estrogen level?

Unlikely: In a women with monthly cycles who ovulates, estrogen levels normally fluctuate from 40-400 pg/ml. Levels above this are unusual unless a hormone producing ovarian tumor. You may be referring to a lack of ovulation with low Progesterone making estrogen dominate. Your gyn can evaluate. ...Read more

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Dr. Christopher Crosby
Board Certified
10 years in practice
92K people helped
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Dr. Deborah Metzger
Board Certified, Obstetrics and Gynecology
33 years in practice
113K people helped
3

3
What are the obvious effects of having high estrogen levels?

What are the obvious effects of having high estrogen levels?

Heavy periods: The symptoms of high estrogen or estrogen dominance are heavy periods with clots, irregular periods that are heavy, water retention, pms, large and tender breasts, growth of fibroids, high blood pressure, diabetes, migraines and severe cramps. These symptoms may also be from Progesterone deficiency. ...Read more

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Dr. Philip Kern
Board Certified, Endocrinology
37 years in practice
2M people helped
4

4
Does high estrogen levels cause me to dislike people?

Does high estrogen levels cause me to dislike people?

Not estrogens: All women have estrogen and it is unlikely your levels are higher than that of other women. Although changes in estrogen levels (eg menopause) can certainly affect mood, estrogen levels should not make you dislike people. ...Read more

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Dr. Christopher Crosby
Board Certified
10 years in practice
92K people helped
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Dr. Regina Hampton
Board Certified, Breast Surgery
17 years in practice
3M people helped
5

5
Is it possible for guys to have high estrogen levels?

Is it possible for guys to have high estrogen levels?

Yes: There are foods, medications and clinical conditions that can cause increased estrogen levels in men. ...Read more

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Dr. Thomas Namey
Board Certified, Rheumatology
42 years in practice
69M people helped
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Dr. Janice Alexander
Board Certified, Obstetrics and Gynecology
36 years in practice
1M people helped
7

7
My E2 levels have ranged from 83 to 114 pmol/L. Do I have high estrogen? My Test. has ranged from 172 to 374 ng/dl.

My E2 levels have ranged from 83 to 114 pmol/L. Do I have high estrogen? My Test. has ranged from 172  to 374 ng/dl.

Not necessarily: Your hormone levels are dependent upon the timing in your cycle. For example, if your E2 level was done in the first part of the cycle, this may be within normal limits.( Normal is 21-251 pg/ml). Your Testosterone level, however, is elevated. Normal is 10-40ng/dl. See your Provider for a discussion regarding this. ...Read more

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Dr. Gerard Honore
Board Certified, Fertility Medicine
23 years in practice
55M people helped
8

8
What is a high estrogen level for 50?

What is a high estrogen level for 50?

Still cycling?: Or not? If menopausal then over 40-50 could be high; if cycling, it can go up to 200 or there about depending on when in the cycle. ...Read more

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Dr. Michael Sinclair
Board Certified, Family Medicine
32 years in practice
7M people helped
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9
Is it true that men with high estrogen levels are actually heavier?

Is it true that men with high estrogen levels are actually heavier?

They can be: Estrogen can cause weight gain and excess fat can convert some testosterone into estrogen. So, it works both ways. Men that are heavy due to muscle building and not fat may actually have lower estrogen levels due to loss of body fat. ...Read more

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Dr. Gerard Honore
Board Certified, Fertility Medicine
23 years in practice
55M people helped
10

10
Could high estrogen levels in a males body affect his gender preference?

Could high estrogen levels in a males body affect his gender preference?

Highly doubtful: Interesting idea but i've never seen any evidence or rationale for why this should be so. Complex social and behavioral issues, such as gender preference and gender identity, are never as simple as a high level of this-or-that hormone! ...Read more

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Dr. Christopher Crosby
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10 years in practice
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