Doctor insights on:
What Happens To Pyruvate And Glutamate When Fasting
You've pushed me---: I've been avoiding this question (as my colleagues have as well). I never was a fan of biochem in college or medical school. But I still have&refer to my Lubert Stryer from time to time...not the most recent edition you understand but mine is SPECIAL. Anyways, I'm still going through the chapter on amino metabolism which partially explains this so stay tuned. I promise to answer this shortly! ...Read more
If you have a glutamate metabolism disorder...& then you eat a food high in glutamic acid (meat, gluten, casein..Etc), what happens to you? Symptoms?
A lot: Glutamate overall is an excitatory protein in the body. It stimulates the perception of taste and appetite. It also acts on the pancreas and liver. Our bodies need some but too much can cause a lot of different problems such as weight gain, diabetes, and neurotoxicity. In addition to avoiding high glutamate foods it is useful to consume extra carnitine (high in red meat) to counter the glutamate. ...Read more
In Heavens name WHY?: Glutamate activates NMDA receptors. Neuronal receptors are proteins that float around in neurons' cell membranes. NMDA receptors are only about 1% of cerebral neuronal receptors but they are widely distributed throughout the entire brain. They play a part in long-term potentiation, which is believed to be one of the mechanisms of learning & memory. Why on EARTH would you want to neutralize that? ...Read moreSee 1 more doctor answer
You flunked the quiz: Excitotoxicity is COMPLICATED. Don't assume you understand it just because you've read a few lines about it here or there. But that's not really relevant to your question. Glutamic acid (glutamate) is NOT an essential amino acid. Your body makes all the glutamate it needs from alanine &/or aspartic acid. Consuming "natural sources" of glutamate simply means your body needs to make less of it. ...Read moreSee 1 more doctor answer
No definitive answer: The so called "glutamate" system has bee implicated in a"hodge podge" of Neurologic and Psychiatric conditions including but "not limited to" Parkinson's Disease, BiPolar Disorder, Autism, and Schizophrenia. NONE OF THIS IS PROVEN! I would be very careful if someone claims that this is related to any problems you may be having! BE WELL ...Read moreSee 1 more doctor answer
Insufficient data: Sorry, "How can glutamate release and reabsorbed?" is not a comprehensible statement. You can see that, right? Please repost it so that it is grammatically coherent and intelligible. ...Read more
Glutamate "rebound": As the name implies, glutamate receptors blocked during ingestion of alcohol (or ketamine) are reactivated ("rebound") after the effects of both are diminished, and high levels of glutamate are then felt with the perceptions of post alcohol withdrawal ("hangover") similar to when one eats foods containing high mono sodium glutamate, a preservative contained in many foods. ...Read more
ALCAT tests: Contact www.alcat.com and ask if there are any of their resources near you. They do set up facilities and doctors world wide. ...Read more
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