Doctor insights on:
What Happens To Children Who Have A Transposition Of The Great Arteries
Arteries are a type of blood vessels. We can divide blood vessels into 2 categories. Arteries are high pressure vessels which deliver (red) oxygen + blood out into the body. Veins on the other hand or low pressure vessels which return (dark) oxygent - blood from the body ...Read more
TGA: Tga refers to a type of congenital heart disease in which the aorta is connected to the right ventricle (instead of the left ventricle) and the pulmonary artery is connected to the left ventricle (instead of the right ventricle). This heart defect usually requires surgical repair within the first several days to weeks of life. ...Read moreSee 1 more doctor answer
Major surgery: Major artery switch procedure at very young age, or sequence of three complex surgeries to make the right ventricle to work like the left one. ...Read more
Two main forms: Classic form (d-TGA) results in severe cyanosis (blue baby). The pulmonary artery arises from the left ventricle and the aorta arises from the right ventricle, resulting in 2 separate circulations in parallel--all the red, oxygenated blood returns to the lungs and the blue, deoxygenated blood goes to the body. Generally results in severe cyanosis and early death if not repaired in early infancy. ...Read more
Cyanosis: Cyanosis, or blue-tinged skin or mucous membranes, is caused by low oxygen levels in the blood (hypoxemia). In transposition of the great arteries, cyanosis is due to the aorta arising from the right ventricle (and the pulmonary artery arising from the left ventricle) which leads to de-oxygenated systemic venous blood being redirected to the body (and oxygenated blood recirculating in the lungs). ...Read more
Congenital: Transposition of the great arteries is a congenital heart defect, meaning that it is an abnormality of cardiac development and is fully present at birth. Classic, or d-tga refers to a disease where the aorta arises from the rv and the pulmonary artery arises from the lv. Diagnosis is typically made early. Another form of tga (l-tga) is a different disease where the rv and the lv are "inverted. ...Read moreSee 1 more doctor answer
True: They are unaffected until born .... This is because of the blood circulation system that is in place for the baby while still in utero. It isn't until after birth, that this circulation changes and from "fetal blood circulation" to "adult blood circulation." often times, these babies will have heart surgery with in just a few days of being born and go on to live very normal lives. ...Read moreSee 1 more doctor answer
Around 2-3 weeks: It really depends on the details and even so, there is significant variability. 2-3 weeks is a rough estimate, though. ...Read more
I'm curious, when a fetus has transposition of the great arteries are they unaffected until they are born?
No: Usually fetuses tolerate the transposition hemodynamics very well in utero and after birth they will be cyanotic (blue). However, it is thought that transposition physiology may affect brain development because the blood with lower oxygen content is what supplies the fetal brain compared to fetuses with normal heart. In general, after repair transposition patient have excellent outcome. ...Read moreSee 1 more doctor answer
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