Doctor insights on:
What Happens In Immunotherapy
Tolerance: Immunotherapy is a treatment that involves exposure of the immune system to gradually increasing doses of an allergen to which the person is allergic. During this gradual increase in dose the immune system becomes tolerant or resistant to the exposure reducing the symptoms that a person has on exposure to those allergens in nature. ...Read moreSee 2 more doctor answers
Encompasses subcutaneous, patch or sublingual treatment with increasing amounts of specific allergen. Used for allergic rhinitis, allergic asthma, and hymenoptera hypersensitivity (and in ongoing trials for food allergy). Specific IgE-mediated disease must be proven. Indications are lack of symptom control despite medication/avoidance, reduce risk of anaphylaxis, or ...Read more
Educate Immune Cell: Immunotherapy involves a retraining of the immune system. This may include therapeutic vaccines or immune checkpoint inhibitors for patients with cancer. The goal is to train the body's immune system to behave more normally for example recognizing and attacking the cancer. This type of therapy has recently gained interest with the approval of immunotherapy agents for prostate cancer and melanoma. ...Read moreSee 1 more doctor answer
Many ways: The best characterized mechanisms are induction of specific t suppressor cells to down regulate the immune response to allergens, and the generation of IgG "blocking" antibodies that bind allergens before they can bind to ige on the surface of mast cells to trigger histamine release. ...Read moreSee 2 more doctor answers
Varied side effects: Radioimmunotherapy such as zevalin or Bexxar (tositumomab) can have multiple side effects: infusion reactions such as fevers, rigors, blood pressure changes, shortness of breath can occur. Serious side effects include low blood counts (fatigue, infections), new blood cancers, skin reactions, impaired fertility. ...Read moreSee 2 more doctor answers
Under supervision: Immunotherapy should be given under the supervision of a physician in a facility equipped with proper staff and equipment to identify and treat adverse reactions to allergy injections. Ideally, immunotherapy should be given in the prescribing allergist/immunologist's office. ...Read moreSee 1 more doctor answer
5 years: Most people see results in as little as 9-12 months, and nearly maximum results by three years, and a full course of therapy is 5 years. Symptoms often start to come back three to five years after stopping immunotherapy, so some patients prefer to continue the shots for much longer than 5 years. ...Read moreSee 2 more doctor answers
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