Doctor insights on:
What Happens If You Stop Taking Methotrexate Suddenly
Methotrexate: You will likely have more swelling, pain, & stiffness, unless you are taking another med or dmard. ...Read more
Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more
Depends on your RA -:
Being controlled or not. Your symptoms might get worse.
You should check with your rheumatologists as they might change it for some other medicine or if you are having side effects from the mtx, you may need some meds to counter those effects. ...Read more
possible flare: Possibly may cause flare, but depends on why stopping. If significant side effect, that outweighs the flare risk. ...Read more
How long does methotrexate stay in your system after you stop taking drug. I am having an allergic reaction to the medicine.
1/2 life depends on dose 3-10 hours with low dose and 8-15 hours with high dose
We usually say it is out after 5 1/2 lives bt there are tissue effects too — maybe 3 weeks ...Read more
I have stopped taking my Crohn's medication (methotrexate)I was suffering severe side effects. I'm still incredibly sick & wondering when it will stop?
Had irregular cycles prior to taking methotrexate, 2 doses for ectopic. Will it make cycle more irregular or cause it to stop permanently?
On methotrexate to control lupus. I can never have children unless I stop this med, but nothing else controls awful symptoms. What are my options?
See below: He/she may experience a flare in his/her symptoms. Let the doctor know what's going on. ...Read more
I have been taking methotrexate, HCG with folic acid, calcium and with another medicine for a month. If I stop taking methotrexate now for how lo?
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My mom has RA will undergo in this two weeks hip replacment surgery.so she should stop taking adalimumab(humira) and methotrexate for surgery?
Probably yes: The operating surgeon will direct you in the correct answer. These medicines may change immune system or risk of bleeding, but only the surgeon has the experience to direct your mom for best outcome. When to stoop and restart is crucial to allow the meds to continue controlling the underlying disease. ...Read more
I have bad acne after taking methotrexate for 6wks. Should I stop using it, or is there something I can take to get rid of it whilst still taking meth?
Wrong doctors: Why aren't you discussing this issue with your own rheumatologist? ...Read more
I have RA and I got small hand deformity am taking methotrexate every saturday and folic acid every sunday. Can that help stop the development?
Yes, sometimes: Methotrexate is a first line therapy for RA in the us and most other therapies are combined with Methotrexate unless it cannot be used. If inflammation is continuing the addition of a biologic agent (humira, enbrel, (etanercept) simponi) may help prevent longterm damage. They have been shown to provide added benefit. ...Read more
Why do I need to stop methotrexate & arava (leflunomide) before alif surgery? I can't take it for 2 months after, why?
I take .8 cc of methotrexate weekly. I had to stop injections for 3 weeks to have my thyroid removed. I started injections last week and have been sick ever since. Any problems if I stop shots?
Always check with: Prescribing doc before making changes in med regimen. S/he can discuss symptoms you're having & provide options for treatment. ...Read more
After about how many weeks do you stop noticing improvement with methotrexate 4 arthritis or lupus where max improvement is reached? ~12 weeks?
Since one year it take 15 mg methotrexate tablet weekly for rheumatoid arthritis so when I can stop it now my blood test is normal but still have pain?
Which blood test etc: Methotrexate is a good medication for rheumatoid arthritis but it doesn't cure your arthritis — it works as long as you take it. If you still have pain, it may because of active disease (inflammation), or damage that the arthritis has already caused. You should follow up with a rheumatologist if possible. ...Read more
I was diagnosed with an ovarian ectopic pregnancy. I was given methotrexate to help stop cell division. Will this affect future fertility?
I'm on injectable methotrexate and prednisone for Dermatomyositits. I need a tooth pulled and a cleaning. Will I need to stop meds prior?
Ask your MD: Dosage and length of time on these meds are important; clotting may be reduced and adrenal glands may be suppressed. Your MD may want to do some blood work prior to an extraction. Should be no problem for a normal cleaning. ...Read more
Is sulfasalazine good stop gap alternative for stopping methotrexate before fathering a child? N do both these meds have negative effect on t level?
Some thoughts: I have seen hundreds of people on Methotrexate for their rheumatoid arthritis and then I agree that hair loss is a bothersome side effect. Nonetheless, at the doses used treat RA I never saw aperson go bald. You're going to have hair loss and there's no good therapy to prevent that. However, some women do notice benefit with using OTC rogaine (minoxidil) in concert with partial hairpieces on social engageme ...Read more
I take methotrexate (15mg) once a week for arthritis. I have to take a 1 dose of diflucan for a yeast infection, do I need to stop the methotrexate?
Methotrexate: This is a really important question for your Rheumatologist, they will know your history best and should be able to give the best advice. ...Read more
Can methotrexate fail to stop an ectopic pregnancy from growing, eventually resulting in the rupture of the fallopian tube from the growing pregnancy?
On second antibiotic for UTI. Keflex and now Cipro (ciprofloxacin). Still, have symptoms. I am on plaquenil and methotrexate for SLE. Should I temporarily stop meds?
Check with doc first: The bacteria that cause UTI can be resistant to many antibiotics. However, it would be unusual for a UTI to resist both cephalexin (Keflex) and ciprofloxacin. But it could happen, so maybe UTI, maybe not. A vaginal yeast infection triggered by the antibiotics could cause UTI-like symptoms. Don't stop treatment yet, but speak with the doctor who prescribed it about next steps. Good luck. ...Read more
It depends: Methotrexate is a potent immunosuppressive medication. It also helps reduce the need for corticosteroids that have significant side effects. Its major side effect is on the liver, causing liver damage; it can affect the lining of the gut; rarely it causes a hypersensitivity inflammation of the lung (Methotrexate pneumonitis). Therefore, patients need to be carefully monitored while on the drug,. ...Read more
Yes: Once you've been cleared by your doctor to start trying for your next pregnancy, you should be fine. Methotrexate is harmful in pregnancy but quickly clears from your body. After one full menstrual cycle, the effects of Methotrexate should be gone. Of course, many other things can affect fertility, including the reason you may have needed Methotrexate in the first place. ...Read more
Also, milk rich food: If you take oral Methotrexate (tablets) along with milk or milk-rich foods, it may decrease absorption. This is not toxic but may result in getting a lower dose than you need to keep your disease under control. This can be avoided by taking injections under the skin of Methotrexate which are not painful and you can guarantee 100% absorption. As you probably know, always avoid any alcohol. ...Read more
Yes: Above 15 mg/wk, more effective (because of reduced GI absorption) and less GI side effects. ...Read more
Works: Methotrexate has become the standard of first choice forra treatment but rarely results in remission, ie no one can tell if you have it including the doctor. The risk is extremely low, although you cannot use alcohol, and is not usually used if ther is preexisting liver disease. Most patients have to add several other disease modifying drugs to get better. ...Read more
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