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Doctor insights on: What Happens If You Stop Taking Methotrexate For Juvenile Rheumatoid Arthritis

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What happens if you stop taking immunosuppressive for rheumatoid arthritis?

What happens if you stop taking immunosuppressive for rheumatoid arthritis?

Comes back: Rarely does RA go into true remission without getting worse after stopping the immunosuppressives. This is particuarly true for methotrexate. Many people have stopped gold therapy without a return of the arthritis for many years. Occasionally biologics can be stopped after several years of remission but the RA usually returns. ...Read more

Methotrexate (Definition)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more


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What happens if you stop taking methotrexate for your arthritis?

What happens if you stop taking methotrexate for your arthritis?

Methotrexate: You will likely have more swelling, pain, & stiffness, unless you are taking another med or dmard. ...Read more

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What would happen if someone stopped their rheumatoid arthritis medication?

What would happen if someone stopped their rheumatoid arthritis medication?

See below: If you are in remission on medication for Rheumatoid Arthritis, under a doctor,s supervision and in remission long enough he may guide you to discontinue. Otherwise, you should never attempt on your own because it can recur worse than ever and the drugs that once worked may not if started again. This disease can damage your joints. ...Read more

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What happens if taking methotrexate for autoimmune diseases?

What happens if taking methotrexate for autoimmune diseases?

It depends: Methotrexate is a potent immunosuppressive medication . It also helps reduce the need for corticosteroids that have significant side effects. Its major side effect is on the liver, causing liver damage; it can affect the lining of the gut; rarely it causes a hypersensitivity inflammation of the lung (Methotrexate pneumonitis). Therefore, patients need to be carefully monitored while on the drug, . ...Read more

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What happens if I do not take medication for my rheumatoid arthritis?

What happens if I do not take medication for my rheumatoid arthritis?

A disaster: You will likely develop progressive joint damage, deformity and disability. This process starts often very early in the disease course. Do not risk it. ...Read more

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What will happen if I do not take medication for rheumatoid arthritis?

What will happen if I do not take medication for rheumatoid arthritis?

Shorter life: Untreated rheumatoid arthritis shortens lives. The effect on the lifespan depends on the severity of the disease and the amount of inflammation. Rheumatoid arthritis commonly causes joint deformities which, if they occur, can only be reversed by surgery. It is best to get prompt diagnosis and treatment. Ra is serious chronic disease like diabetes. ...Read more

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What medications should I take for juvenile arthritis?

What medications should I take for juvenile arthritis?

MTX & TNF-inhibitor: Kids tolerate the combination of weekly Methotrexate injected under the skin(mtx)and a tnf-inhibitor(enbrel, humira, (adalimumab) remicade)so well, there is no reason to not start both medications.The goal in children should be no active arthritis.There is not the same risk of infections that adults have w/ meds.Kids are growing and anything less than total remission of their disease can inhibit normal growth. ...Read more

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Can you tell me about taking the disease modifying drug (dmards) for their psoriatic arthritis?

Can you tell me about taking the disease modifying drug (dmards) for their psoriatic arthritis?

See details: The two major DMARDs for treating psoriatic arthritis are Methotrexate and the biologics such as Remicade, (infliximab) Enbrel and Humira among others. All are extremely effective, especially the biologics. All have potential side effects such as infection risk, reduced blood counts and liver disease. ...Read more

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What happens when you stop taking methotrexate for ra?

Depends on your RA -: Being controlled or not. Your symptoms might get worse. You should check with your rheumatologists as they might change it for some other medicine or if you are having side effects from the mtx, you may need some meds to counter those effects. ...Read more

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I started taking lefluomide for rhematoid arthritis for about 3 mos. The precautions concern me. Can i stop taking this immediately or gradually?

I started taking lefluomide for rhematoid arthritis for about 3 mos. The precautions concern me. Can i stop taking this immediately or gradually?

Talk to doc.: Can stop immediately, but... I am sure you are taking this medication for a very good reason and have not done well on some of the other meds. I am sure you are being monitored by a rheumatologist. Before stopping this med you should sincerely consider the return of your underlying disease and discuss with your doctor. ...Read more

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What are drugs you can take for rheumatoid arthritis?

What are drugs you can take for rheumatoid arthritis?

Many!: Methotrexate, sulfasalazine, hydroxychloroquine, doxycycline, minocycline, cyclophosphamide, azothioprine and more! then, you have the tnf-alpha drugs: humira, remicade, enbrel, cimzia, and more. Then other biologics: Rituxan and orencia (abatacept). New drugs will shortly be online as well! ...Read more

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What happens if i stop taking medication for sjrogrens syndrome?

Symptoms will return: If you stop the medication the symptoms will return. ...Read more

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Dr. Liawaty Ho Dr. Ho
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I would like to know experience on taking rituxan (rituximab) for rheumatoid arthritis?

Dr. Liawaty Ho Dr. Ho
1 doctor agreed:
I would like to know experience on taking rituxan (rituximab) for rheumatoid arthritis?

Good experience: Rituxan (rituximab) has been used in rheumatoid arthritis and it has demonsrated good response-in my experience. Jus like anything else, there are some possible side effects from Rituxan (rituximab) but majority are very tolerable. You need to be screened for hepatitis b - prior to Rituxan (rituximab) administration.-as Rituxan (rituximab) can cause hep b exacerbation. ...Read more

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My daughter taking naproxin for joint pain/ possible jra. How long before we notice a difference!? If this don't work what are other meds ?

My daughter taking naproxin for joint pain/ possible jra. How long before we notice a difference!? If this don't work what are other meds ?

See rhemstologist: There are other drugs available but they best be administered by a rheumatologist, because of their long term needs and side effects. ...Read more

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I would like to know advice on taking rituxan (rituximab) for rheumatoid arthritis?

I would like to know advice on taking rituxan (rituximab) for rheumatoid arthritis?

Great choice: Rituxan (rituximab) is a very effective medication for rheumatoid arthritis. People do very well some go into remission. Remission is our goal in treating rheumatoid arthritis. Your rheumatologist will decide with you if this is the best choice for you. ...Read more

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How common is it to use both methotrexate and hydroxychloroquine in treating juvenile arthritis? Is this safe? What should I know before starting?

JiA treatment: For multi-drug therapy for jia, Methotrexate is more commonly paired with biologic medication. For methotrexate, watch for mouth sores and nausea. Blood testing will be needed to check blood counts and liver tests. For treatment with plaquenil, (hydroxychloroquine) plan to have annual eye exams. ...Read more

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What kind of doctor do I see for juvenile rheumatoid arthritis?

What kind of doctor do I see for juvenile rheumatoid arthritis?

Get proper treatment: Be sure to see a board certified pediatric rheumatologist.General pediatricians and family medicine docs are not familiar or comfortable with using weekly low dose Methotrexate and TNF inhibitors that are needed to control 99% of kids with correctly diagnosed JIA/JRA.It's worth traveling some distance to see a pediatric rheumatologist since most adult rheumatologists do not treat it as effectively ...Read more

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Dr. Hamid Sajjadi
40 doctors shared insights

Rheumatism (Definition)

"rheumatism" is an older term, not used much today. Most people are referring to pain and swelling in the joints when they use this term. People may mean something different when they use this term in contrast to when they refer ...Read more


Dr. Robert Lowe
1,569 doctors shared insights

Painful Joints (Definition)

That term is not really a specific diagnosis, but rather somewhat of a general term. The medical term is arthralgias, which implies pain in multiple joint possibly coming from a single cause. Don't hesitate to be seen and evaluated for ...Read more