Doctor insights on:
What Happens If You Stop Taking Methotrexate For Autoimmune Diseases
It depends: Methotrexate is a potent immunosuppressive medication . It also helps reduce the need for corticosteroids that have significant side effects. Its major side effect is on the liver, causing liver damage; it can affect the lining of the gut; rarely it causes a hypersensitivity inflammation of the lung (Methotrexate pneumonitis). Therefore, patients need to be carefully monitored while on the drug, . ...Read moreSee 1 more doctor answer
In auto immune disease the enemy is from with in . As name implies "auto" is self and "immune " is immune system . One 's own immune system for unknown reason turns against self and destroys or damages tissues or cells . List of auto immune disease are many and growing . End result is destruction of of tissues such as thyroid , pancreas or cells such as white ...Read more
Comes back: Rarely does RA go into true remission without getting worse after stopping the immunosuppressives. This is particuarly true for methotrexate. Many people have stopped gold therapy without a return of the arthritis for many years. Occasionally biologics can be stopped after several years of remission but the RA usually returns. ...Read more
Depends on your RA -: Being controlled or not. Your symptoms might get worse. You should check with your rheumatologists as they might change it for some other medicine or if you are having side effects from the mtx, you may need some meds to counter those effects. ...Read more
Wean off: Slowly. Though not a overly high dose. Still want to wean slowly off. 30 mg day for week -10 days. Then 20. Etc. could even do it slower. It could cause adrenal gland to not work properly. Cause extreme fatigue. Jt pains body aches. To name. Few. Call your doctor to set up weaning protocol. ...Read more
possible flare: Possibly may cause flare, but depends on why stopping. If significant side effect, that outweighs the flare risk. ...Read more
A disaster: You will likely develop progressive joint damage, deformity and disability. This process starts often very early in the disease course. Do not risk it. ...Read more
I started taking lefluomide for rhematoid arthritis for about 3 mos. The precautions concern me. Can i stop taking this immediately or gradually?
Talk to doc.: Can stop immediately, but... I am sure you are taking this medication for a very good reason and have not done well on some of the other meds. I am sure you are being monitored by a rheumatologist. Before stopping this med you should sincerely consider the return of your underlying disease and discuss with your doctor. ...Read moreSee 1 more doctor answer
Yes : It helps some, owing from its antiplatlet effects, but not a lot. ...Read more
Is treatment necessary for systemic mastocytosis? I am taking gleevec (imatinib). What would happen if i stopped taking it?
D/w oncologist: There are indolent systemic masto, and agressive systemic mastocytosis (asm). Many times, with indolent disease- therapy will be aimed only to control the symptoms- itching, diarrhea etc. If you have an asm- then usually treatment is started. Asm can manifest from slowly progressive to rapid fatal disease.Organ involvement , transformation to other blood DX including acute leukemia can happen. ...Read more
What would happen if you take a high dose of prednisone for a lupus flare but are told to just stop it after 7 days? What could potentially happen?
See details: If there was a significant flare then 7 days is too brief a period. Sudden stoppage would likely cause the flare to recur. ...Read more
What to do if I have psoriatic arthritis. I take 3 lortab 10 pills a day. If i stop taking the pills what are the withdraw?
Could you tell me what happens when you don't take Synthroid (thyroxine) for hypothyroidism and start taking it again?
Shorter life: Untreated rheumatoid arthritis shortens lives. The effect on the lifespan depends on the severity of the disease and the amount of inflammation. Rheumatoid arthritis commonly causes joint deformities which, if they occur, can only be reversed by surgery. It is best to get prompt diagnosis and treatment. Ra is serious chronic disease like diabetes. ...Read more
The immune system developed to tell our own, normal cells (self) from foreign and abnormal cells (non-self). This lets the immune system eliminate viruses, bacteria, fungi and cancer cells from our body without harming normal cells. Sometimes the immune system fails to tell self from non-self and it attacks normal cells, for example in ...Read more
Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more
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