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Doctor insights on: What Happens If You Stop Taking Methotrexate For Autoimmune Diseases

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What happens if taking methotrexate for autoimmune diseases?

What happens if taking methotrexate for autoimmune diseases?

It depends: Methotrexate is a potent immunosuppressive medication . It also helps reduce the need for corticosteroids that have significant side effects. Its major side effect is on the liver, causing liver damage; it can affect the lining of the gut; rarely it causes a hypersensitivity inflammation of the lung (Methotrexate pneumonitis). Therefore, patients need to be carefully monitored while on the drug, . ...Read more

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Dr. Tracy Lovell
486 doctors shared insights

Autoimmune Disease (Definition)

In auto immune disease the enemy is from with in . As name implies "auto" is self and "immune " is immune system . One 's own immune system for unknown reason turns against self and destroys or damages tissues or cells . List of auto immune disease are many and growing . End result is destruction of of tissues such as thyroid , pancreas or cells such as white ...Read more


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Is methotrexate for autoimmune diseases?

Is methotrexate for autoimmune diseases?

Yes, good for many: Low dose weekly Methotrexate is an excellent and safe drug (as long as you don't drink alcohol) that is useful for treating a number of autoimmune diseases either alone or combination with other drugs. I sometimes use it in kids with an autoimmune disease where the exact diagnosis is not clear since it is excellent for long term control of inflammation without the use of steroids. Talk to your doc. ...Read more

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I have PAD pos ANA. Muscle joint pain. What are early symptoms of autoimmune disease flare? I have rheumy. Stop seeing because I wasn't having symps

I have PAD pos ANA. Muscle joint pain. What are early symptoms of autoimmune disease flare? I have rheumy. Stop seeing because I wasn't having symps

Define PAD: PAD means peripheral artery disease. This would be unusual in your age group depending on the rest of your symptoms and findings. A +ANA is seen is autoimmune disease but is only a clue and by itself is not diagnostic. It can be seen in other clinicial settings and is not diagnostic alone.You best decision is to return to see your rheumatologist. ...Read more

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Might methotrexate help w/dysautonomia symptoms caused by autoimmune disorder like lupus when standard tx (floninef & salt)don't' work but prednisone does?

Might methotrexate help w/dysautonomia symptoms caused by autoimmune disorder like lupus when standard tx (floninef & salt)don't' work but prednisone does?

May not be best: Dysautonomia due to lupus could be due to neurological involvement such as autonomic neuropathy, or due to adrenal suppression as a consequence of prolonged steroid treatment. In the first case Methotrexate might not be a strong enough immunosuppressor; its role in lupus is mainly limited to treating arthritis. In the second case, the treatment would be supplemental steroids such as florinef (fludrocortisone). ...Read more

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What do autoimmune diseases attack?

What do autoimmune diseases attack?

Autoimmune diseases : In auto immune disease the enemy is from with in . As name implies "auto" is self and "immune " is immune system . One 's own immune system for unknown reason turns against self and destroys or damages tissues or cells . List of auto immune disease are many and growing . End result is destruction of of tissues such as thyroid , pancreas or cells such as white cells , platelets etc. ...Read more

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Are autoimmune diseases very common?

Yes.: Most people with hypothyroidism have the disease hashimoto's thyroiditis. When you add psoriasis, colitis to the diseases ra, spondyloarthritis, type 1 diabetes, and onward, you have a majorpercentage of american's having an "autoimmune disease. ...Read more

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What can cause an autoimmune disease?

What can cause an autoimmune disease?

Autoimmune diseases : In auto immune disease the enemy is from with in . As name implies "auto" is self and "immune " is immune system . One 's own immune system for unknown reason turns against self and destroys or damages tissues or cells . List of auto immune disease are many and growing . End result is destruction of of tissues such as thyroid , pancreas or cells such as white cells , platelets etc. ...Read more

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How does someone get autoimmune disease?

How does someone get autoimmune disease?

Autoimmune disease: It is not fully understood and reasarch is still on . It happens in idividuals who are genetically susceptible triggered by an offending agent which could be a bacteria, virus, environemental toxins , drugs , food allergens , radiation, chemicals , hormonal to name a few . It is a flu like onset with fatigue followed by symtoms referable to the target organ, tissue or cell that is affected. ...Read more

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Autoimmune (Definition)

The immune system developed to tell our own, normal cells (self) from foreign and abnormal cells (non-self). This lets the immune system eliminate viruses, bacteria, fungi and cancer cells from our body without harming normal cells. Sometimes the immune system fails to tell self from non-self and it attacks normal cells, for example in ...Read more


Methotrexate (Definition)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more