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Doctor insights on: What Happens If You Stop Taking Methotrexate For Autoimmune Diseases

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What happens if taking methotrexate for autoimmune diseases?

What happens if taking methotrexate for autoimmune diseases?

It depends: Methotrexate is a potent immunosuppressive medication . It also helps reduce the need for corticosteroids that have significant side effects. Its major side effect is on the liver, causing liver damage; it can affect the lining of the gut; rarely it causes a hypersensitivity inflammation of the lung (Methotrexate pneumonitis). Therefore, patients need to be carefully monitored while on the drug, . ...Read more

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Dr. Tracy Lovell
501 doctors shared insights

Autoimmune Disease (Definition)

In auto immune disease the enemy is from with in . As name implies "auto" is self and "immune " is immune system . One 's own immune system for unknown reason turns against self and destroys or damages tissues or cells . List of auto immune disease are many and growing . End result is destruction of of tissues such as thyroid , pancreas or cells such as white ...Read more


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What happens if you stop taking immunosuppressive for rheumatoid arthritis?

What happens if you stop taking immunosuppressive for rheumatoid arthritis?

Comes back: Rarely does RA go into true remission without getting worse after stopping the immunosuppressives. This is particuarly true for methotrexate. Many people have stopped gold therapy without a return of the arthritis for many years. Occasionally biologics can be stopped after several years of remission but the RA usually returns. ...Read more

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What happens if you stop taking methotrexate for your arthritis?

What happens if you stop taking methotrexate for your arthritis?

Methotrexate: You will likely have more swelling, pain, & stiffness, unless you are taking another med or dmard. ...Read more

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What happens when you stop taking methotrexate for ra?

Depends on your RA -: Being controlled or not. Your symptoms might get worse. You should check with your rheumatologists as they might change it for some other medicine or if you are having side effects from the mtx, you may need some meds to counter those effects. ...Read more

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What happens if you have a liver transplant and you stop taking anti rejectipn drugs?

What happens if you have a liver transplant and you stop taking anti rejectipn drugs?

Transplant rejection: If you stop taking your medications, the transplanted liver will be rejected, leading to irreversible damage and eventually liver failure. ...Read more

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What happens if you smoke while taking rituximab?

What happens if you smoke while taking rituximab?

Tobacco bad: There are many reasons not to smoke, but i don't know of a specific interaction between smoking and rituximab. ...Read more

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What happens if you abruptly stop taking prednisone after being on 40mg for a year? Can you die?

What happens if you abruptly stop taking prednisone after being on 40mg for a year? Can you die?

Wean off: Slowly. Though not a overly high dose. Still want to wean slowly off. 30 mg day for week -10 days. Then 20. Etc. could even do it slower. It could cause adrenal gland to not work properly. Cause extreme fatigue. Jt pains body aches. To name. Few. Call your doctor to set up weaning protocol. ...Read more

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Can u get lupus if you stop taking hydralazyne. The medicine for hbp?

Can u get lupus if you stop taking hydralazyne. The medicine for hbp?

See details: First of all, Hydralazine is rarely used anymore as a treatment for hypertension so i would suggest alternatives. If you stop the med then a drug induced lupus would be extremely unlikely. ...Read more

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Is it advisable to stop taking methotrexate suddenly for skin diseases?

Is it advisable to stop taking methotrexate suddenly for skin diseases?

possible flare: Possibly may cause flare, but depends on why stopping. If significant side effect, that outweighs the flare risk. ...Read more

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What happens if you stop taking thyroid meds?

What happens if you stop taking thyroid meds?

You will get sick: If you stop medication for any medical problem, the problem will get worse and you will get sick. It's really a simple concept. Proper medication helps you treat or prevent illness; non-compliance and denial leads to sickness and death. ...Read more

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What happens if I do not take medication for my rheumatoid arthritis?

What happens if I do not take medication for my rheumatoid arthritis?

A disaster: You will likely develop progressive joint damage, deformity and disability. This process starts often very early in the disease course. Do not risk it. ...Read more

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I started taking lefluomide for rhematoid arthritis for about 3 mos. The precautions concern me. Can i stop taking this immediately or gradually?

I started taking lefluomide for rhematoid arthritis for about 3 mos. The precautions concern me. Can i stop taking this immediately or gradually?

Talk to doc.: Can stop immediately, but... I am sure you are taking this medication for a very good reason and have not done well on some of the other meds. I am sure you are being monitored by a rheumatologist. Before stopping this med you should sincerely consider the return of your underlying disease and discuss with your doctor. ...Read more

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Dr. Liawaty Ho Dr. Ho
2 doctors agreed:
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Is treatment necessary for systemic mastocytosis? I am taking gleevec (imatinib). What would happen if i stopped taking it?

Dr. Liawaty Ho Dr. Ho
2 doctors agreed:
Is treatment necessary for systemic mastocytosis? I am taking gleevec (imatinib). What would happen if i stopped taking it?

D/w oncologist: There are indolent systemic masto, and agressive systemic mastocytosis (asm). Many times, with indolent disease- therapy will be aimed only to control the symptoms- itching, diarrhea etc. If you have an asm- then usually treatment is started. Asm can manifest from slowly progressive to rapid fatal disease.Organ involvement , transformation to other blood DX including acute leukemia can happen. ...Read more

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What happens if you are taking the hep c treatment, what dose?

What happens if you are taking the hep c treatment, what dose?

Depends: If you are on hepatitis C therapy, you have a good chance of being cured with the newer medications now. However, I don't know what you mean by what dose? Your liver doctor can adjust your ribavirin dose based on your blood counts. ...Read more

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What would happen if you take a high dose of prednisone for a lupus flare but are told to just stop it after 7 days? What could potentially happen?

What would happen if you take a high dose of prednisone for a lupus flare but are told to just stop it after 7 days? What could potentially happen?

See details: If there was a significant flare then 7 days is too brief a period. Sudden stoppage would likely cause the flare to recur. ...Read more

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Could you tell me what happens when you don't take Synthroid (thyroxine) for hypothyroidism and start taking it again?

Could you tell me what happens when you don't take Synthroid (thyroxine) for hypothyroidism and start taking it again?

Nothing: It takes time for Synthroid (thyroxine) to build up in your body. If you stop Synthroid (thyroxine) and start again, you might feel hypothyroid for the 1-2 weeks it takes for Synthroid (thyroxine) to reach steady state. ...Read more

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What will happen if I do not take medication for rheumatoid arthritis?

What will happen if I do not take medication for rheumatoid arthritis?

Shorter life: Untreated rheumatoid arthritis shortens lives. The effect on the lifespan depends on the severity of the disease and the amount of inflammation. Rheumatoid arthritis commonly causes joint deformities which, if they occur, can only be reversed by surgery. It is best to get prompt diagnosis and treatment. Ra is serious chronic disease like diabetes. ...Read more

Autoimmune (Definition)

The immune system developed to tell our own, normal cells (self) from foreign and abnormal cells (non-self). This lets the immune system eliminate viruses, bacteria, fungi and cancer cells from our body without harming normal cells. Sometimes the immune system fails to tell self from non-self and it attacks normal cells, for example in ...Read more


Methotrexate (Definition)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more