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Doctor insights on: What Happens If You Stop Taking Methotrexate For Arthritis

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What happens if you stop taking methotrexate for your arthritis?

What happens if you stop taking methotrexate for your arthritis?

Methotrexate: You will likely have more swelling, pain, & stiffness, unless you are taking another med or dmard. ...Read more

Dr. Thomas Namey
2,357 doctors shared insights

Arthritis (Definition)

Arthritis is progressive degeneration of one or more joints. Symptoms may include joint pain, swelling, decreased motion, and stiffness. The two most common types of arthritis are osteoarthritis, which is associated first with articular cartilage breakdown with a component of inflammation, and rheumatoid arthritis, which is a systemic autoimmune disorder that affects joint linings first and secondarily ...Read more


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After about how many weeks do you stop noticing improvement with methotrexate 4 arthritis or lupus where max improvement is reached? ~12 weeks?

After about how many weeks do you stop noticing improvement with methotrexate 4 arthritis or lupus  where max improvement is reached? ~12 weeks?

Yes: Three months is reasonable to expect the maximum response to Methotrexate at the specific dose you take. If you still have issues, consider increasing the Methotrexate dose. 25 mg weekly is generally considered to be the maximum weekly dose for the conditions you mention. ...Read more

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Since one year it take 15 mg methotrexate tablet weekly for rheumatoid arthritis so when I can stop it now my blood test is normal but still have pain?

Since one year it take 15 mg methotrexate tablet weekly for rheumatoid arthritis so when I can stop it now my blood test is normal but still have pain?

Which blood test etc: Methotrexate is a good medication for rheumatoid arthritis but it doesn't cure your arthritis - it works as long as you take it. If you still have pain, it may because of active disease (inflammation), or damage that the arthritis has already caused. You should follow up with a rheumatologist if possible. ...Read more

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What are effects of taking methotrexate for rheumatoid arthritis?

Works: Methotrexate has become the standard of first choice forra treatment but rarely results in remission, ie no one can tell if you have it including the doctor. The risk is extremely low, although you cannot use alcohol, and is not usually used if ther is preexisting liver disease. Most patients have to add several other disease modifying drugs to get better. ...Read more

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Do I take methotrexate for arthritis?

Do I take methotrexate for arthritis?

For inflammatory art: Methyltrexate is not use for degenerative arthritis but inflammatory arthritises like rheumatoid arthritis. ...Read more

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Is it thought of as dangerous to take methotrexate for rhematoid arthritis?

Absolutely not...: Low dose (10 to 25mg) weekly Methotrexate is probably the best, most effective first line medication for ra. However, if you drink alcohol (any) or have pre-existing liver disease, Methotrexate can be harmful.Your doctor will need to check your liver enzymes monthly for 3 months, then every 3 months while on Methotrexate to make sure your liver is okay. Do not take if pregnant--it can kill the baby. ...Read more

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Are there more risks or benefits with use of weekly methotrexate as injection vs oral for arthritis or ctds. Why is oral usually prescribed?

Are there more risks or benefits with use of weekly methotrexate as injection vs oral for arthritis or ctds. Why is oral usually prescribed?

No: There is no increased risk in fact many believe the injectable form is better as it gets directly into bloodstream and does not depend on absorption from the gut. ...Read more

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For juvenile arthritis is methotrexate safe?

For  juvenile arthritis is  methotrexate  safe?

Very safe!: Although i frequently use other agents for jia, i frequently add mtx to the therapeutic mix. Considering that the dose should be lower, i still favor the subcutaneous route rather than oral. However, I have not had serious issues with mtx and children. Make sure they get supplemental folic acid! ...Read more

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Methotrexate (Definition)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more


Dr. Robert Lowe
1,461 doctors shared insights

Painful Joints (Definition)

That term is not really a specific diagnosis, but rather somewhat of a general term. The medical term is arthralgias, which implies pain in multiple joint possibly coming from a single cause. Don't hesitate to be seen and evaluated for ...Read more