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Doctor insights on: What Happens If You Stop Methotrexate Abruptly

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What happens if you stop taking methotrexate for your arthritis?

What happens if you stop taking methotrexate for your arthritis?

Methotrexate: You will likely have more swelling, pain, & stiffness, unless you are taking another med or dmard. ...Read more

Methotrexate (Definition)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more


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What happens when you stop taking methotrexate for ra?

What happens when you stop taking methotrexate for ra?

Depends on your RA -: Being controlled or not. Your symptoms might get worse. You should check with your rheumatologists as they might change it for some other medicine or if you are having side effects from the mtx, you may need some meds to counter those effects. ...Read more

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Is it advisable to stop taking methotrexate suddenly for skin diseases?

Is it advisable to stop taking methotrexate suddenly for skin diseases?

possible flare: Possibly may cause flare, but depends on why stopping. If significant side effect, that outweighs the flare risk. ...Read more

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On methotrexate to control lupus. I can never have children unless i stop this med, but nothing else controls awful symptoms. What are my options?

On methotrexate  to control lupus. I can never have children unless i stop this med, but nothing else controls awful symptoms. What are my options?

Azathioprine or plaq: Plaquenil (hydroxychloroquine) is the safest to be on for pregnancy and in severe lupus we use azathioprine as it not as toxic to a fetus. Talk to your rheumatologist to see what you are a candidate for. ...Read more

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Had irregular cycles prior to taking methotrexate, 2 doses for ectopic. will it make cycle more irregular or cause it to stop permanently?

Had irregular cycles prior to taking methotrexate, 2 doses for ectopic. will it make cycle more irregular or cause it to stop permanently?

May or may not: it may not make you have a normal cycle. This is something you can ask your physician. You may need to do discuss this with the gynecologist. ...Read more

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Why do I need to stop methotrexate & arava (leflunomide) before alif surgery? I can't take it for 2 months after, why?

See details: Two months is an unusually long period to hold Methotrexate after surgery. Three weeks is more the usual but it is ultimately up to your surgeon. ...Read more

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After about how many weeks do you stop noticing improvement with methotrexate 4 arthritis or lupus where max improvement is reached? ~12 weeks?

After about how many weeks do you stop noticing improvement with methotrexate 4 arthritis or lupus  where max improvement is reached? ~12 weeks?

Yes: Three months is reasonable to expect the maximum response to Methotrexate at the specific dose you take. If you still have issues, consider increasing the Methotrexate dose. 25 mg weekly is generally considered to be the maximum weekly dose for the conditions you mention. ...Read more

Dr. Robert Lowe
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Rheumatrex (Definition)

Rheumatrex ...Read more