Doctor insights on:
What Happens If You Don't Take Anti Rejection Drugs
NO: The grafting material, unless it is your own bone, usually only provide a scaffold for your blood vessel to proliferating and bring in your own bone cell, differentiate, and mature into your bone. Anti rejection drug applied more for using a live graft (an organ, bone marrow, etc.) and assuming its function. Thus anti rejection drug is not prescribed for bone graft procedure. ...Read moreSee 2 more doctor answers
Depends: There are certain anti-rejection meds with significant drug-drug interaction that makes it necessary to take them separately. A good example is cyclosporine and sirolimus and one needs to take them separately (usually 4 hrs apart). I encourage you to speak to your transplant physicians/nurse coordinators for detailed information. ...Read more
Rejection risk: Hi. Rejection depends on multiple variables, and therefore is fairly unpredictable. Why has the patients skipped 3 consecutive doses? I would recommend talking with the transplant physician to see what needs to be done. Rejection is not a good thing. This patient should be more compliant with the antirejection regimen. Good luck to the patient! ...Read more
What if you forget to take your anti rejection meds on time, but do take them a couple hours later every day?
For the first time in almost a year I forgot to take the morning dose of anti rejection meds. What should I do?
Hard to say.: Immunosuppression medications are necessary to prevent the body from attacking the transplanted kidney. If the medications are stopped, the body begins to attack (reject) the organ and the kidney will eventually fail. Once this happens, dialysis will need to be started. Many factors affect the rate at which the body attacks the kidney, making an exact answer to your question difficult. ...Read more
Is it safe to stop anti rejection drugs for organ transplant after 3 years since no complications developed?
People have anti-rejection drugs for organ replacement why can't you have the same for blood transfusions?
Depends: If you miss just one dose of anti-rejection meds, the risk of that precipitating a rejection is likely low. However, it is the repeated non-compliance with meds that often leads to poor patient and graft outcome. I encourage patients to have extra meds with them if they are going out (in case they cannot get back in time). Your immune system has a very good long-term memory. ...Read more
Safer than Rejection: All medicines have side effects. It's the job of the transplant clinic to find the right cocktail for each patient which will prevent rejection with minimal side-effects. Because most patients are on combination therapy, there is a great deal of art as well as science which goes into finding the best combination of drugs. ...Read moreSee 1 more doctor answer
Affects your levels: If you drink grapefruit juice or eat grapefruits your Prograf levels will be higher. This may cause your surgeon to lower your dose then when you are not enjoying your grapefruit your levels will be low and your grafts will be at risk for rejection. ...Read more
No: After spinal fusion, I would recommend you avoid nsaids or steroids. These inhibit inflammation which actually helps the fusion process to complete. Otherwise, meds as prescribed by your surgeon and resumption of other medication prescribed by other doctors is fine (even blood thinners generally ok a week or so after fusion). Rejection meds are not typically used after spine fusion. ...Read moreSee 1 more doctor answer
Needs clarification: I believe you are asking whether anti-rejection medications cause damage to the heart. Anti-rejections themselves do not cause coronary artery disease but organ transplant recipients are at increased for cardiovascular disease. Some anti-rejection meds can cause or contribute to worsening hypertension, high cholesterol, or diabetes and therefore increase the risk of heart disease and stroke. ...Read moreSee 1 more doctor answer
I have had a kidney transplant 14 years ago what are the chances of getting off some anti rejection pills?
What does a steroid resistance transplant mean? Are steroids first line for anti-rejection prophylaxis?
Steroids: In the old days- which really is in the last 29 years steroids have always been first line therapy for transplants. Recently physicians have been moving to steroid- free protocols because of the side effects of steroids including diabetes, weight gain and bone disease. Steroid resistant if that is what you mean may be someone who is not a candidate for steroid therapy. ...Read more
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