Doctor insights on:
What Group Of People Is Most Commonly Affected With Sickle Cell Anemia
This is a genetic disorder in which hemoglobin is abnormally made., more common in people of african descent. This abnormality causes red blood cells to become stiff and fall apart. This can cause very specific symptoms: pain, pneumonias, strokes, spleen problems, and many other problems. Some have mild disease, some ...Read more
Genetics: Sickle cell disease is a condition caused by inheriting two copies (one from each parent) of a mutated beta-hemoglobin gene. Sickle cell disease does help lessen the symptoms of certain diseases like malaria, and this is why certain ethnic groups that lived at one time in malaria-prone regions of the world (such as africa) have a higher incidence of carrying the sickle cell gene. ...Read more
The beta globin gene: Hemoglobin is a complicated molecule in red blood cells that carries oxygen from the lungs to the rest of the body. It contains 4 protein chains, 2 Alpha chains and 2 beta chains. Sickle cell disease is caused by specific mutation in the beta globin gene. We each have two beta globin genes. If one has the s mutation you have sickle trait; if both have the s mutation you have sickle cell anemia. ...Read moreSee 1 more doctor answer
I have sickle cell anemia, B+ blood group, Hgb 7.4 gd/l.
what should I do to transfer blood if I have antibody reciptents screening are positive?
Blood bank question: If I understand your question, you have an antibody that makes it possible for you to accept blood from certain donors beyond the limits of the ABO system. Your local blood bank handles this although we appreciate your wish to educate yourself about these deep matters. If blood is hard to find and you need it, you have our sympathy; you may be a candidate for a high-tech therapy. ...Read more
Yes in a mild: Case, but would be more typical in sickle trait than disease. ...Read more
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