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Doctor insights on: What Gland Is Affected By Paget's Disease

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What endocrine gland does paget's disease of bone harm?

What endocrine gland does paget's disease of bone harm?

None: While called an endocrine disorder, to my knowledge, there is no specific organ/gland damage. Any pathologist can to weigh in? ...Read more

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Who is at risk for paget's disease?

Who is at risk for paget's disease?

Anyone: There are some genetic associations, but the disease can affect anyone. ...Read more

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Is Pagets disease an example of an eponym?

Is Pagets disease an example of an eponym?

Yes: An eponym is a person, a place, or thing for whom or for which something is named. Sir James Paget first described Paget disease (PD) of the breast in 1874. He also described Pagets disease of bone. He served both as a well known surgeon as well as Pathologist in the mid 18 hundreds . His famous works included Lectures on Tumours (1851) and Lectures on Surgical Pathology (1853) ...Read more

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How can paget's disease effect my eyesight?

How can paget's disease effect my eyesight?

Pagets and eye: Pagets disease increases bone density which can gradually close off nerves and blood vessels in any part of the body that they pass through. There are a few cases in which the nerves and vessels leading to the eye are narrowed affecting the health and vision of the eyes. ...Read more

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What're the clinical findings of the Paget's disease?

What're the clinical findings of the Paget's disease?

Nipple changes: Paget's disease of the breast is a type of cancer that involves the nipple and/or the dark tissue around the nipple (areloa). Often there is another tumor within the breast. Symptoms involve the nipple and include crusting, thickening, itching, scabbing or bleeding. There are many non-cancerous reasons for nipple symptoms, but if you have changes that don't resolve, see your health provider! ...Read more

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Is paget's disease fatal?

Is paget's disease fatal?

Which?: Paget's disease of bone is a relatively benign and self-limited condition which can sometimes cause pain and in the worst case, deformity or fragility. But paget's disease of the breast is often a manifestation of an underlying breast cancer, which can certainly be fatal if untreated. ...Read more

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Is paget's disease treatable?

Is paget's disease treatable?

Yes: Paget's disease is very treatable. I have several paget's patients who do very well on yearly Reclast (zoledronic acid) infusions. ...Read more

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Can paget's disease be contagious?

Can paget's disease be contagious?

No: Some evidence suggests a virus might be involved in the cause but it still is not contagious. ...Read more

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Does paget's disease show up on an x-ray?

Does paget's disease show up on an x-ray?

Paget's disease: Of bone appears on bone scans and plain x-rays of the effected bone. Paget's disease of nipple and skin are distinct, different and not visible on imaging of any kind, suspected by exam, proven by biopsy. ...Read more

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Is paget's disease cancerous in all cases?

Is paget's disease cancerous in all cases?

In Situ or Invasive: Paget's dz represents less than 5% of all breast cancers; cancer cells are found involving the skin of the nipple, resembling eczema.Over 95% of the time an underlying cancer is found elsewhere in the breast, more commonly in-situ rather than invasive. Traditional rx was mastectomy however central lumpectomy (removal of nipple and areola) followed by radiation therapy is an acceptable alternative. ...Read more

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Is there a paget's disease support group online?

Is there a paget's disease support group online?

Several: Try http://www.Experienceproject.Com/groups/have-pagets-disease-of-bone/99046.

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What can you tell me about paget's disease? Is this deadly?

What can you tell me about paget's disease? Is this deadly?

Occassionally: Pagets disease of bone is seen as marked swelling with bone deformity, altering the shape of the bone involved such as femur hip region. In some instances malignant transformation to Pagets sarcoma develops. this is especially true in the skull where marked deformity in the side or top of head seen and sarcomatous malformation can lead to brain invasion. ...Read more

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Is there a national organization for paget's disease patients?

Is there a national organization for paget's disease patients?

Paget Foundation: The paget foundation, http://www.Paget.Org, is one organization. Related groups: http://www.Pagetitalia.Com, http://www.Paget.Org.Uk, http://www.Paget.Nl, http://www.Rarebonedisease.Org, http://www.Magicfoundation.Org, http://www.Fibrousdysplasia.Org, http://www.Nof.Org, http://www.Bones.Nih.Gov, http://www.Oif.Org, and http://www.Boneandcancerfoundation.Org. ...Read more

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Does paget's disease significantly decrease a persons lifespan?

Does paget's disease significantly decrease a persons lifespan?

Stage-Dependent: Paget's dz represents less than 5% of all breast cancers; cancer cells are found involving the skin of the nipple, resembling eczema.Over 95% of the time an underlying cancer is found elsewhere in the breast, more commonly in-situ rather than invasive. Traditional rx was mastectomy however central lumpectomy (removal of nipple and areola) followed by radiation therapy is an acceptable alternative. ...Read more