Doctor insights on:
What Exactly Is Nephritis And What Are The Causes
A little vague term: The term nephritis generally means inflammation of the kidneys filtering units. The usual term is glomerulonephritis gn. However, whatever term you use is not adequate to describe the underlying mechanism of disease. That is why the full terms are membranous glomerulonephritis, minimal glomerulonephritis, hereditary nephritis etc. If you have nephritis ask you doctor for the full name/description. ...Read moreSee 1 more doctor answer
Obsolete: "Trench Nephritis" is an obsolete term for glomerulonephritis..It goes back to World War I when a lot of soldiers developed it. There are different types of nephritis (inflammation of microscopic anatomical portions of the kidney called the glomeruli). There are different types of nephritis but hen the term is used without specifying,they usually are referring to glomerulonephritis.Hope this answe ...Read moreSee 1 more doctor answer
Kidney structure: Kidney specialists look at kidney as 3 compartments- glomerulus, tubulointerstitial and vascular.Tubulointerstitium consists of tubules and interstitium involved in absorption/secretion of electrolytes, water and acids. When diseases affect this part, it is called tubulointerstial nephritis. ...Read more
Eclampsia: During some pregnancies there can be a state of toxemia related to abnormal placental function which leads to acute kidney damage and severe hypertension sometimes with convulsions. The kidneys suffer damage to blood vessels with excessive coagulation and loss of filtration first heralded by protein in the urine. ...Read more
Autoantibodies: Lupus nephritis is produced when autoantibodies cause inflammation of the kidney glomeruli and tubules. It is one of the organs affected by lupus Often a biopsy needed to determine severity and prognosis-class I,II,III, IV, V, and VI, with six being the most severe. Treatment includes corticosteroid, azothioprin, cyclophosamide, mycophenelate mofetil,cyclosporin. dialysis. Remission can occur. ...Read more
Kidney nephritis- can high dose Valacyclovir/Valtrex (4g daily)cause it?
Negative ANA but mild kidney nephritis consistent with ckd.
Sle pt on cellcept (mycophenolate mofetil). If cellcept (mycophenolate mofetil) can cause increased bun why is it used for lupus nephritis? Also can it increase creatinine?
Methotrexate: Methotrexate in high doses can cause be toxic to the kidney, causing kidney injury. The term "nephritis" is usually reserved for a specific disease process rather than drug-induced damage. Methotrexate is a well-known cause of mucositis or mouth sores. ...Read moreSee 2 more doctor answers
I am a19 year old female, recovering from kidney problem (lupus nephritis) caused by sle. I am under medication and improving, but my face, skin and lips are pale and anemic. Why could it be?
Benign GN - opinion: Benign nephritis is a term used by a nephrologist to describe his/her opinion of a patient's condition. Usually this term is attached to patient's with nonproteinuric IgA nephropathy, thin basement membrane disorder, or recovered post infectious gn. It is an opinion, it is not a guarantee, but when used by a nephrologist it usually means low risk of progression to esrd. ...Read more
See below: The most common symptoms of nephritis will typically be elevated blood pressure with values sometimes extremely elevated, increased swelling of the feet and legs from fluid retention which then will result in weight gain. Shortness of breath can occur if fluid builds up in the lungs. Obviously labs will be abnormal including kidney function abnormalities and abnormal urine tests. ...Read more
Changes in the urine: Nephritis means inflammation of the kidney. This can sometimes result in blood or protein being lossed in the urine manifesting as a smoky or frothy urinary appearance nephritis can result in kidney injury and as such, patients may present with feelings of fatigue, swelling and elevated blood pressure. In may instances, nephritis causes no symptoms and is picked up incidentally bo routine labs. ...Read more
Inflammation: Nephritis refers to inflammation of the kidney, and can be acute or chronic. It has a variety of causes. Nephrosis is a degenerative disease, usually of a specific part of the kidney called the renal tubule. A nephrosis is generally thought of as any kidney disease that is non-inflammatory. ...Read moreSee 1 more doctor answer
Nephritis: You did not mention what type of nephritis you had at age 15. Have you had any episodes of it since? If you spent 10 years without seeing a physician and had no problem with your kidneys, you are probably fine. To confirm that, however, you need to see either physician, preferably a nephrologist to make sure. Good luck. ...Read more
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