Doctor insights on:
What Exactly Is Nephritis And What Are The Causes
A little vague term: The term nephritis generally means inflammation of the kidneys filtering units. The usual term is glomerulonephritis gn. However, whatever term you use is not adequate to describe the underlying mechanism of disease. That is why the full terms are membranous glomerulonephritis, minimal glomerulonephritis, hereditary nephritis etc. If you have nephritis ask you doctor for the full name/description. ...Read moreSee 1 more doctor answer
Obsolete: "Trench Nephritis" is an obsolete term for glomerulonephritis..It goes back to World War I when a lot of soldiers developed it. There are different types of nephritis (inflammation of microscopic anatomical portions of the kidney called the glomeruli). There are different types of nephritis but hen the term is used without specifying,they usually are referring to glomerulonephritis.Hope this answe ...Read moreSee 1 more doctor answer
Kidney structure: Kidney specialists look at kidney as 3 compartments- glomerulus, tubulointerstitial and vascular.Tubulointerstitium consists of tubules and interstitium involved in absorption/secretion of electrolytes, water and acids. When diseases affect this part, it is called tubulointerstial nephritis. ...Read more
Eclampsia: During some pregnancies there can be a state of toxemia related to abnormal placental function which leads to acute kidney damage and severe hypertension sometimes with convulsions. The kidneys suffer damage to blood vessels with excessive coagulation and loss of filtration first heralded by protein in the urine. ...Read more
Autoantibodies: Lupus nephritis is produced when autoantibodies cause inflammation of the kidney glomeruli and tubules. It is one of the organs affected by lupus Often a biopsy needed to determine severity and prognosis-class I,II,III, IV, V, and VI, with six being the most severe. Treatment includes corticosteroid, azothioprin, cyclophosamide, mycophenelate mofetil,cyclosporin. dialysis. Remission can occur. ...Read more
Kidney nephritis- can high dose Valacyclovir/Valtrex (4g daily)cause it?
Negative ANA but mild kidney nephritis consistent with ckd.
Sle pt on cellcept (mycophenolate mofetil). If cellcept (mycophenolate mofetil) can cause increased bun why is it used for lupus nephritis? Also can it increase creatinine?
Methotrexate: Methotrexate in high doses can cause be toxic to the kidney, causing kidney injury. The term "nephritis" is usually reserved for a specific disease process rather than drug-induced damage. Methotrexate is a well-known cause of mucositis or mouth sores. ...Read moreSee 2 more doctor answers
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