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Doctor insights on: What Effect Does Altitude Have On A Person With Sickle Cell Trait And Why

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What effect does altitude have on a person with sickle cell trait and why ?

What effect does altitude have on a person with sickle cell trait and why ?

Sickle in low oxygen: A person with sickle cell trait only, is ok at sea level, but at high altitudes can get sickling in his red blood cells due to the lower concentration of oxygen at high altitudes. The problem of sickled cells clogging off the spleen is rare, but has happened to some people exercising above 10, 000 feet. Good hydration and avoiding over-exertion might decrease the chances of problems starting. ...Read more

Dr. James Ball
348 doctors shared insights

Sickle Cell Disease (Definition)

This is a genetic disorder in which hemoglobin is abnormally made., more common in people of african descent. This abnormality causes red blood cells to become stiff and fall apart. This can cause very specific symptoms: pain, pneumonias, strokes, spleen problems, and many other problems. Some have mild disease, some ...Read more


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I have sickle cell trait,I heard being at high altitudes could be dangerous,Can taking a 16+hour flight harm me?

I have sickle cell trait,I heard being at high altitudes could be dangerous,Can taking a 16+hour flight harm me?

Possibly. : Great question. An airplane flight puts you at the equivalent of 8 to 10 thousand feet of elevation depending on the plane. That can cause sickling in patients with sickle cell trait. Ask your doctor whether you should wear oxygen for the flight. Stay very well-hydrated, and keep warm with blankets and layers! If you have trouble on the flight, oxygen is the key. ...Read more

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If I have sickle cell trait is it possible to now be sickle cell anemia?

If I have sickle cell trait is it possible to now be sickle cell anemia?

Confusing question: SS disease requires the genes for sickle cell from both parents, while S trait has it from one. You cannot change the genetic makeup that you were born with. Someone with trait can have a kid with SS if the partner has trait or SS. ...Read more

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If me and boyfriend both have sickle cell trait, how will we prevent our children from having full sickle cell anemia?

If me and boyfriend both have sickle cell trait, how will we prevent our children from having full sickle cell anemia?

Nothing: Unfortunately, there would be 25% chance for your child to have sickle cell disease and 50% chance for sickle cell trait . With our technology now, nothing can alter the risk. Sorry to say , the only thing for somebody with sickle cell trait to completely prevent any possibility of having a biological child with sickle cell disease is by having a child with somebody with normal hb. ...Read more

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If a child has sickle cell anemia, wouldn't both the parents need to have sickle cell trait?

If a child has sickle cell anemia, wouldn't both the parents need to have sickle cell trait?

No: There are varying forms of sickling diseases, however it is a recessive trait and so the parents may appear fine but carry the trait and yet have a child with the disease. ...Read more

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Could both parents have to have the sickle cell trait for the child to have sickle cell anemia?

Could both parents have to have the sickle cell trait for the child to have sickle cell anemia?

Yes: Sickle cell anemia requires the gene from both parents to cause ss anemia. If only one parent gave the gene, the kid would be a trait carrier. ...Read more

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Do both parents have to have the sickle cell trait for the child to have sickle cell anemia?

Do both parents have to have the sickle cell trait for the child to have sickle cell anemia?

No: 2 abnormal (sickle cell) gene have to be inherited to have sickle cell disease. This can happen if both patents have sickle cell trait, one parent has sickle cell disease or both have sickle cell disease. ...Read more

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Can a father with normal blood and a mother with sickle cell trait have a child with sickle cell anemia?

Can a father with normal blood and a mother with sickle cell trait have a child with sickle cell anemia?

NO: To simplify- providing that the father has a completely normal blood - ( no other type of congenital/hereditary bood disorder-like thalasemia minor, hemoglobin c disease etc) - the baby will have 50% risk to have sickle cell trait-but the baby will not have sickle cell anemia. ...Read more

Dr. Oscar Novick
73 doctors shared insights

Sickle Cell Carrier (Definition)

Sickle cell trait is a genetic condition where a person has one gene copy for the abnormal hemoglobin protein. Having two gene copies would cause red blood cells ...Read more