What dose of prednisone is considered for immunosuppression - Doctor answers

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Does hashimoto's thyroiditis cause immunosuppression? Can prednisone cause latent TB to become active in a patient with chronic sinusitis?

Does hashimoto's thyroiditis cause immunosuppression? Can prednisone cause latent TB to become active in a patient with chronic sinusitis?

Two questions: 1) no hashimoto's thyroiditis is a auto- immune disease which does not cause immune suppression.
2) chronic use of steroids (prednisone) can cause immune-suppression and can modify response to PPD (TB test). ...Read more

Dr. Thomas Namey
2,557 Doctors shared insights

Prednisone (Definition)

Prednisone is a synthetic cortisone. The body makes cortisone, a natural hormone made in adrenal glands. The body converts it to Hydrocortisone to become active. 25 mg of cortisone has about same effect as 5 mgm prednisone. The average person would produce 3-6 mg of pred daily. So why use a substitute? The synthetic has more anti-inflammatory effect; but has less effect ...Read more


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What is the typical starting dose of prednisone?

What is the typical starting dose of prednisone?

Depends: Depends on your age (pediatric vs. Adult), and the medical condition. ...Read more

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What is the tapering dose of prednisone?

What is the tapering dose of prednisone?

See below: Tapering is a gradual decrease in the does over weeks to months until the lowest possible dose is reached. ...Read more

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What is the recommended dose of prednisone when using for anti inflammatory?

What is the recommended dose of prednisone when using for anti inflammatory?

Varies: The dose of Prednisone varies with the severity of the inflammatory p roblem. Many conditions can be successfully treated with small doses but life-threatening problems may require very large amounts of steroids. The goal is always to use the least amount of Prednisone for the shortest possible time. ...Read more

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How long will I withdraw off iv prednisone after having 5 doses and no taper down?

How long will I withdraw off iv prednisone after having 5 doses and no taper down?

Probably won't: Adrenal insufficiency (steroid withdrawl) is usually only an issue after long term therapy. Doses less than 60 mg for 5 days or less don't usually require a taper. ...Read more

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Can high dose prednisone temporarily cause elevated glucose of 147 in nondiabetics?

Can high dose prednisone temporarily cause elevated glucose of 147 in nondiabetics?

Yes: Steroids are known to increase glucose but affects should subside shortly after the steroids are discontinued ...Read more

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On day 5 of 7 of prednisone (going 7654321-per day). Very fidgety will ride it out...When will this nervousness go away-after last dose?

Restlessness is: Considered a short-term side effect of Prednisone and should stop shortly. It likely has some dose-dependent property to this side effect, and you are almost done. The half-life of Prednisone is 1 hour, so it is out of your system 5 hours after taking it. Best wishes. ...Read more

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Why might I be getting foggy, confused, & in an almost disoriented state at times when tapering my prednisone dose below 6 mg? Been on almost 1 yr.

Why might I be getting foggy, confused, & in an almost disoriented state at times when tapering my prednisone dose below 6 mg? Been on almost 1 yr.

Adrenal insuff: Hi, how long have you been on Prednisone? What is the average dose you were taking in last year? You might have a condition called 2/2 Adrenal insufficiency due to suppression of Adrenal glad due to chronic use of Prednison. You might need slower and longer tapering. Talk to an Endocrine doctor. Good luck. ...Read more

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Ck enzimes have been running high for the past 6 years at least. Range : 600 - 1935 u/l. Low dose prednisone helps :5mg. What is the cause of this?

Ck enzimes have been running high for the past 6 years at least. Range : 600 - 1935 u/l. Low dose prednisone helps :5mg. What is the cause of this?

Several possibles: There are many issues that can cause elevation of muscle enzymes. The major ones are meds (most commonly statins) and diseases that can cause muscle inflammation of damage. I would urge a rheumatology consultation. ...Read more

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I was on a 15day (60mg for 5days, 40mg for 5days, & 20mg for 5days) dose of prednisone for hives. How long will the meds continue to treat the hives?

Hives: Once you stop the Prednisone the hives may return. The most important way to stop the hives is to find the cause. You may want to see an Allergist to determine what is causing your hives. ...Read more

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Feels like I need to defecate all the time. Is this related to being on prednisone? Just finished my 5 day dose last week and that's when this started

Feels like I need to defecate all the time. Is this related to being on prednisone? Just finished my 5 day dose last week and that's when this started

Chicken or egg here?: Hard to determine from your limited information if your concern as expressed reflects medication, or the underlying condition for which prednisone was prescribed. Why have you taken it? ...Read more

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Taken 2 doses of mobic (meloxicam) and would like to swap to prednisone for quicker onset. How long do I have to wait to start prednisone after last dose of mobic (meloxicam)?

Not interchangeable: Mobic (meloxicam) is a non steroidal and is used as a general treatment or arthritis, bursitis, tendinitis, etc...Prednisone is only used as a powerful ant inflammatory in diseases such as rheumatoid arthritis, lupus, vasculitis. It is not interchangeable with nsaids. You should only use Prednisone for these autoimmune type conditions and only with close supervision. ...Read more

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Why would my Dr. Decline a refill on a previously prescribed 20mg dose of Prednisone for a recurring pinched nerve?

Why would my Dr. Decline a refill on a previously prescribed 20mg dose of Prednisone for a recurring pinched nerve?

Recurrent radicular: I would never prescribed more than one course of steroids for an episode of radiculopathy. Even one course maybe too many. If does not resolve with rest, anti-inflammatory medication, physical therapy and epidural injection, then surgeryrecommended. Steroids only relief while taking them and infrequently give any long-term benefit while ensuring long-term harm. ...Read more

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Can prednisone make you feel angrier and almost psychotic? Dose was 20mg for 5 days, on 2nd day of 10mg two days to go.

Can prednisone make you feel angrier and almost psychotic? Dose was 20mg for 5 days, on 2nd day of 10mg two days to go.

Yes: Indeed it can have this side effect, and it is not uncommon. It should be getting better as you lower the dose, and it should go away. ...Read more

Dr. Henry Selke
141 Doctors shared insights

Immunosuppression (Definition)

Our immune systems are complex, with defense functions against external threats and internal functions that define us as unique individuals. Therapeutic medications to control diseases of overactivity of the immune system (like lupus) or to prevent rejection of transplanted organs we want to trick the body into considering "self" have consequences caused by unwanted ...Read more


Dr. John Feola
988 Doctors shared insights

Liquid Pred (Definition)

Liquid Pred is a corticosteroid which is a kind of ...Read more