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Doctor insights on: What Does Uptake Mean On A Bone Scan

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What does radiopharmaceutical uptake from a bone scan mean in layman's terms?

What does radiopharmaceutical uptake from a bone scan mean in layman's terms?

Tracer uptake: Read the report. But it sounds like it means that there is increased bone metabolism at that location. The radiopharmaceutical maps calcium activity (osteoblastic) of the bone. Can have increased metabolism in response to mechanical stress, a fracture, cancer, infection, and miscellaneous reasons. ...Read more

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Dr. Daniel Lebowitz
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Bone (Definition)

Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more


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Increased uptake on bone scan on left humerus, I suffer from psoriatic arthritis as well as ankylosing spondilitis. what does this mean?

In joint or not: If this is in either end of the humerus near or in the joint it could be due to your psoriatic spondyloarthropathy. If in the shaft and there is no injury it requires further investigation. ...Read more

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Dr. Daniel Lebowitz
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What does increased uptake around the area of the left acetbulum mean? Have had two hip replacements, last one in 1999. Bone scan shows significant bone lose and CT shows increased uptake around the area of the left acetabulum as well as the femoral comp

What does increased uptake around the area of the left acetbulum mean? Have had two hip replacements, last one in 1999.  Bone scan shows significant bone
lose and CT shows increased uptake around the area of the left acetabulum as well as the femoral comp

Uptake on bone scan: Bone scan after injection of IV radiotracer is sensitive for changes in bone metabolism. Increased uptake is not specific but can be related to infection, fracture, loosening or even tumor. However ct shows anatomy and pathology. The loss of bone can occur from lack of normal weight bearing or disuse. Demineralization around stem of prosthesis can be loosening. You should consult your doctor. ...Read more

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Bone scan "increased uptake bilateral SI joints, left greater than right likely due to stresses" Can this mean stress fractures??

Bone scan "increased uptake bilateral SI joints, left greater than right likely due to stresses" Can this mean stress fractures??

This could B a--: -stress fx if of sudden onset, if have had back pain 4 yrs you could have a spondylolysis @ that level. CT images are the best to see a defect as well as determining if stress or developmental. ...Read more

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My bone scan says there is mild generalized increased uptake in left ankle and mid foot and in 1st met. Phalangeal areas. What does this mean?

Why the bone scan: Bone scans are done to evaluate for bone tumors, bone metastasis , infection, and occult fractures such as stress fractures. The study will often be mildly abnormal with arthritis. Your results sound like arthritis, and should be compared to the x-rays of your feet and ankles. ...Read more

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What does strong uptake on a bone scan mean?

What does strong uptake on a bone scan mean?

Increased activity: Strong uptake on bone scan means increased metabolic bone activity. This could indicate inflammation, fracture, infection, and/or bone tumor. These results usually are considered in the face of plain x-rays and exam to determine the diagnosis. Sometimes mri/ct scan are also needed. ...Read more

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Dr. Daniel Lebowitz
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What does nonarticular osteoblastic focus mean on a bone scan?

What does nonarticular osteoblastic focus mean on a bone scan?

Increased uptake: Osteoblastic is term for new bone formation usually describing radiographic appearance. Translated to bone scan this means increased uptake which can be bone repair of infection, fracture, or tumor. Bone scans are very sensitive to bone turnover but not specific. Some primary bone tumors are osteoblastic in that they form bone. Nonarticular means focus of uptake away from a joint. ...Read more

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Will a bone scan light up an area where an bone tumor was removed years before or does it mean the tumor has possibly returned?

Will a bone scan light up an area where an bone tumor was removed years before or does it mean the tumor has possibly returned?

See details: A nuclear medicine bone scan would show areas where there is active bone remodeling (creation) happening. If the surgery was many years ago, the uptake in that region should not be more than other normal areas. If it is more prominent, suggest possible tumor recurrence. More imaging studies like MRI would be indicated and final biopsy for confirmation. ...Read more

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Loved one's bone scan points to possible metastatic cancer, but all blood tests and mammogram are negative for cancer. Any ideas on what it could mean?

Loved one's bone scan points to possible metastatic cancer, but all blood tests and mammogram are negative for cancer. Any ideas on what it could mean?

Positive bone scan: A bone scan is performed following the injection of isotope, usually technetium 99m mdp. This radiotracer is accumulated in the skeleton. There can be areas of increased, decreased and normal uptake of the radiopharmaceutical. Bone scan is very sensitive for detecting lesions but not specific. Fractures, infection, arthritis, and tumors can be detected. Correlation with other imaging is necessary. ...Read more

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