Doctor insights on:
What Does Rpr Vdrl Syphilis Nonreactive Mean
Screening tests.: Vdrl (venerial disease research laboratory) tests against anti-cardiolipin antibodies and RPR (papid plasma reagin) tests against nonspecific antibodies suggestive of syphilis and are screening tests. Treponemal antibody tests, like fta-abs and mha-tp usually become positive two to five weeks after the initial infection. These are used to confirm syphilis and stay positive, even after therapy. ...Read more
Rapid plasma reagin (rpr) is a blood test that looks for non-specific antibodies that may indicate that the organism (treponema pallidum) that causes syphilis is present. The term "reagin" means that this test does not look for antibodies against the actual bacterium, but rather for antibodies against substances released by cells when they ...Read more
Antibodies: Ok. Lets separate these first. The venereal disease research laboratory test or vdrl is a blood test for syphilis and was developed by the former venereal disease research laboratory. Rapid plasma reagin (rpr) refers to a type of test that looks for non-specific antibodies in the blood of the patient that may indicate that the organism (treponema pallidum) that causes syphilis is present. ...Read more
How accurate would a RPR test be for late latent syphilis (approx. 24-30 months after unprotected sex)? Or would a FTA-ABS/VDRL be more accurate?
Confirmatory test: You need to have a confirmatory test (sometimes called an fta) to tell the difference between a false postivite test, which is common, and a true infection. ...Read more
Syphilis testing: All syphilis is "bad": it is a very dangerous infection, even if causing no symptoms at this time. However, low positive results might indicate you were treated without knowing it, e.g. if you received certain antibiotics for other infections. Or it might be a false positive test, so confirmatory testing is needed. Discuss w/ your doctor, or best to see an STD or infectious diseases specialist. ...Read more
I was tested for syphilis. RPR was pisitive (1:1) and TPPA was negative. Does in mean I am infected?
My RPR was Postive with titer 1:1 for syphilis but my FTA-ABS was Non Reactive. What does that mean? I'm being treated.
Syphilis: You need to ask your treating physician to explain thes results to you ...Read more
I had syphilis in 2014. The RPR was 1:128. Got 3 penicilin shots. My most recent blood test shows RPR 1:4. does that mean I got reinfected?
Probably not: Successful cure is defined by a 3-dilution decline in RPR or VDRL titer. Your decline is 5 diultions, so probably all is well. However, if your titer previously declined to a lower level, i.e. negative or under 1:4 and now has risen to 1:4, reinfection is possible. Best to discuss with the doctor or clinic where you were treated, but most likely no problem. ...Read more
I might have been infected with syphilis four years ago. A few months ago I recieved an RPR test and the results were nonreactive. Am I in the clear?
Unclear: Were you treated? What is the result of the confirmatory test? Would have that done. ...Read more
I might have been infected with syphilis four years ago. I just got an RPR test and the results were nonreactive. I was never treated. Am I uninfected?
I might have been infected with syphilis 4 years ago. To check, six months ago I received an RPR blood test and the results were nonreactive. Am I ok?
No Syphilis: Yes. But, if you have any doubts get another test. But, non-reactive means negative. ...Read more
Absolutely: If whoever tested you is on top of things, you've already been advised to have a more specific test. ...Read more
Asked yesterday but question was not really answered. Which comes positive first for syphilis RPR or cia?
CIA?: An appropriate syphilis test involves two stages: the RPR is done FIRST- if positive, a confirmatory test such as an "FTA-ABS' or an "EIA for TPA" must be done. The 2-stage test is more cost effective and decreases the number of 'false positive' results. Discuss this important question further with your ordering doctor. ...Read more
RPR: Rapid plasma regain- Because many things can cause a false positive. So - it is a screening test. ...Read more
RPR: An RPR is a screening test for syphilis. It looks for antibodies present in the blood of people who may have the disease. A negative test is considered normal. A positive test may mean that you have syphilis. However, false positives can occur. If the screening test RPR is positive, the diagnosis is confirmed with more specific testing. ...Read more
Can RPR test for syphilis give false negative? If syphilis is highly suspected should I retest for it?
False (-) in RPR syphilis testing occurs when there is a prozone effect. Why? It's because the concentration of syphilis antibodies is so high, it interferes with the antigen-antibody interactions that result in a (+) reaction. A false (-) result can also occur during primary syphilis since not enough time has
passed to allow high enough antibody levels for a (+) reaction to occur. ...Read more
Have a headache that's persited for 4days now. Minds feels cloudy. Suspecting syphilis had RPR was negative. Supected exposure was 4years ago.
Regarding syphilis:could being on 2 antibiotics (metordinazole, ciprofloaxine) in october give a false negative to RPR test done in december?
How long would the RPR syphilis test be accurate after infection. Would it be accurate between 1-2 years after exposure or is it less reliable then?
Very reliable: First, RPR is no longer the usual first blood test for syphilis. Most labs now start with an IgG ELISA. Either this or RPR is always positive within 6 weeks. In other words, a negative test more than 6 weeks after the last posssible exposure, including 1-2 years, proves you do not have active syphilis. However, a positive results isn't necessarily reliable; positives require confirmatory testing. ...Read more
Wife pregnant, had +rpr 1:1 the confirm done by CIA -, 2.5 weeks later tested again RPR - and eia- 6.5, weeks since last sex. All clear on syphilis?
Wife is pregnant has + RPR 1:1, negative confirmatory by ClIA, negative. 2 weeks later RPR negative and eia negative (6.5 weeks after last sex). All clear on syphilis?
Yes she is: Hi. I read a few of your consults with other doctors on Health Tap. Many of them have advised that you followup with your own doctor to get additional testing. The world is not perfect. Occasionally labs produce errors. The first test may be a false positive. If the test is repeated more than once with negative results then assume you are negative for Syphilis. ...Read more
How worried should I be about the prozone phenomenon in RpR test when ive tesded nonreactive for both HIV 4th Gen and syphilis at 2, 8, and 14 weeks.
Will antinuclear antibody test detect dormant syphilis? I am waiting on results and had a RPR test came back was non reactive.
Can psoriasis cause biological false positive syphilis (RPR)? can I have BFP syphilis and have nothing wrong with me and never get autoimmune disease?
If my blood test is reactive for syphilis both on the RPR and fta-abs lab tests should I get another blood test to confirm?
No: That is how the diagnosis is made. You should get treated. ...Read more
I keep get biological false positive syphilis (through rpr) I don't have lupus. I do have psoriasis. Can I have BFP and never get autoimmune disease.
Yes: Plenty of folks have biologic false positives and are otherwise completely healthy. ...Read more
Hello doctor, I had syphilis and I was treated and I did a vdrl test and it came weak reactive. What does this mean??
Imm (une memory last: Your immune system may always have a small positive antibody response to the former presence of the syphilis, and the very weak reaction (via RPR) indicates past treatment was effective. If you are referring to confirmatory testing for infectivity still being positive, then it is also possible that you have been re=exposed and may need retreatment. Please be sure of which test and discuss with PCP ...Read more
Hello doctor, I had a vdrl test and it came out weak reactive. Does this mean I stil have syphilis? And what drug do u sugest, I am using doxycycline
Not always: VDRL is still time honored inexpensive test for mass screening of syphilis, some times will give false positive results, then need as in yours, more specific tests like like RPR, FTA-RBS etc type of tests are needed Check with your doctor, Doxycycline may not be right drug, First diagnosis has to be established before undergoing any treatment. ...Read more
8 months post possible exposure, results of VDRL and TPHA tests are non-reactive. Can these results be considered conclusive for not having Syphilis?
Yes, conclusive: These tests are conclusive any time 6 weeks or more after the last possible exposure. ...Read more
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