Doctor insights on:
What Does Polycystic Kidney Disease Do To The Body
See below: Polycystic kidney disease is a inherited disease in which fluid filled cavities ranging from microscopic to larger sizes upto 10-15 cm occur in the kidneys, causing them to grow very big and loose function. The patients may have no symptoms or present with blood in urine and sometimes kidney pain.Besides controlling high blood pressure there is no definitive treatment yet.Many studies are ongoing. ...Read more
The kidneys are paired organs that lie on either side of the vertebral column. Part of their critical functions include the excretion of urine and removal of nitrogenous wastes products from the blood. They regulate acid-base, electrolyte, fluid balance and blood pressure. Through hormonal signals, the kidneys control the ...Read more
Not cured: Other than by kidney transplant. Polycystic kidney disease is not universally fatal. Impaired kidney function can be controlled for a long time by diet ; control of hypertension if present. Occasionally symptomatic cysts can be marsupialised laparoscopically. But, as yet, there is no medical treatment to eliminate the cysts. Many require eventual dialysis or transplant. ...Read more
Cause- unknown: Exact etiology for PKD unknown. Some researchers swear that genetics plays a big role-- hence ADPKD and ARPKD ( autosomal dominant type and recessive type). But then there are other tapers not genetically oriented. Some hypothesize-- something goes wrong in signaling at cellular level during renal development--- pronephro/ mesonephros/ metabephros stages! ...Read more
Inherited disease: You inherit polycystic kidney disease, so it is reasonable to be evaluated if you have a parent with polycystic kidneys. Evaluation will likely include a painless ultrasound (sound wave) examination. If you know you have polycystic kidneys, you want to do everything you can to protect their function. At some point, though, you may need dialysis or a transplant. Talk to your doctor. LGromkoMD ...Read more
Genetics etc: Most common is autosomal dominant polycystic kidney disease, adpkd, 50 % of offspring will develop it. Much less common is infantile or autosomal recessive polycystic renal disease, arpkd, inherited by 25% of kids of same parents who are both "carriers". Neither curable, infantile requires treatment from birth with early nephrectomy + dialysis ; transplantation. Adpkd ok early, slowly progressive. ...Read more
Huge kidneys: Dominant or adult PKD often presents with huge kidneys with cysts. High blood pressure, pain in the kidneys, and strokes may also be issues. The kidneys lose function over time on blood tests. Recessive or infantile PKD presents earlier in life. Kidneys are huge but cysts often are not seen. High blood pressure and kidney problems can occur. Liver scarring can also lead to bleeding from the gut. ...Read moreSee 1 more doctor answer
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