Doctor insights on:
What Does Platelet Over 500 Mean
Clumping together: Platelets are sticky cells thus they can stick and clump together. As a result of platelet clumping, platelet counts reported by automated counters may be much lower than the actual count in the blood because these devices cannot differentiate platelet clumps from individual cells. ...Read more
Thrombocytopenia: It means you could be easily. There are different levels of low platelets. Depending on how low, your overall health, your medications, comorbid medical condition your doctor will determine the proper treatment. Normal level is >150, 000. Most people don't have problems if above 100, 000. Below 100, 000 needs more attention. ...Read more
Large platelets: The mpv is a measure of how large the platelet is. Large platelets are presumptively young platelets. If the platelets are being used up or destroyed rapidly (dic or itp) then younger platelets are released into the blood and this is reflected in an increase in the mpv. Also some hereditary platelet disorders cause high mpv. ...Read more
Various: Low= error in test, increased breakdown or decreased production. Some sampling methods (fingerstick)are more prone to give inacurate results. Antibodies can form in certain conditions that destroy plts soon after they are made or they can be used up quickly in excessive clotting states. The production sites in the bone marrow can be invaded & shut down as in leukemia. ...Read more
Normal: I consider this a normal platelet level. ...Read more
What does Minimally reduced final aggregation in response to ADP with disaggregation (final aggregation approximate 30%) means in platelet aggrigation?
Platelet aggregation: The platelet test measures 2 phases - initial ability of platelets to plug leaks, and the secondary reaction of clumps of platelets to stick together (aggregate). Some drugs (like ASA or NSAIDS /ibuprofen) and other structural (genetic) defects can reduce secondary aggregation, which can increase risk of bleeding. Your result could be caused by taking 1 ASA weeks ago. ...Read more
Bleeding risk: Low platelets can mean an increase risk of bleeding. Bleeding can even happen without good cause. The lower the platelet count, the higher the risk for bleeding. The bleeding can be nosebleeds, gum bleeding, heavy periods. The most concerning bleeding would be bleeding inside the skull. This is unusual, but would likely cause a headache and nausea. ...Read more
Thrombocytosis: A high platelet count can be seen in many different conditions, both benign and malignant: iron deficiency anemia, following splenectomy and other types of surgery, in association with cancer, and as a result of a group of bone marrow disorders known as myeloproliferative neoplasms. It is very important that a high platelet count be evaluated promptly by a hematologist. ...Read more
It depends: There is a wide range over which platelet counts can go before raising any concerns. Normally they range between 150, 000 to 400, 000. if your count is over 450, 000, get it rechecked. If the count rises above 500, 000, you should get yourself checked by a hematologist (blood cancer specialiist ...Read more
? thousand?: Platelet counts are usually given as hundreds of thousands per ml of blood. As a means of shorthand communication, they may be stated without the zeros, so "652" likely means 652, 000. This is somewhat high, and might merit investigation but your doctor will know best the circumstances in which this may fit. If it is really only 652, that is dangerously low, and you need to be in a hospital asap. ...Read more
Need more info: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, your count is higher than normal. A common cause of high platelet count is iron deficiency. Your doctor who ordered the test should have more information and should be able provide an opinion if further investigation is warranted. ...Read more
Thrombocytosis: High platelet count is indicative of either a primary bone marrow myeloproliferative disorder or a secondary cause like iron deficiency, stress. Primary disorders include et essential thrombocytosis are driven by jak2 mutation or CML driven by bcrabl mutation. High platelets cause risk of vascular thrombosis, tia, cva, mi. Underlying cause have to be diagnosed and treated to normalize counts. ...Read more
Range of normals: Platelet volume reference range is the range in size of platelets in a normal population of people. A "reference range" is also called the "range of normal" or "normal limits", indicating that if you are in that "range, " you are presumed also to be normal. Certain diseases are associated with large platelets (itp, or myeloproliferative disorders), and some with small platelets (iron deficiency). ...Read more
Iron deficiency Anem:
You have anemia, most probabely iron deficiency due to excessive blood loss during menstruation and elevated platlets we don't have the number is coincidental finding and do not need any therapy
check with your doctor you MCV and MCH values must be low as well
consult your doctor you may need iron therapy. ...Read more
It's normal!: The range for normal platelets is between 150 and 300 in most labs. Your count of 144 is shorthand for 144, 000 platelets per microliter of blood in your body. A microliter is about the tiniest water droplet you could see with your naked eye, about the size of the period in this sentence. So your count of 144 is just a little lower than normal, but not enough that I would be concerned. ...Read more
Need more info:
It would be helpful to know the results of complete blood count. High platelet count is often a side effect of iron deficiency. All lab results need to be interpreted in the clinical context and the doctor who ordered the test is usually in the best position to do that. See this site for more info.
http://www. Mayoclinic. Org/diseases-conditions/thrombocytosis/basics/definition/con-20032674. ...Read more
Could be reactive:
Many secondary cause including infection or underlying inflammatory conditions.
Also bleeding, iron deficiency or people whose spleens have been removed.
Sometimes, more associated with older populations conditions associated with primary bone marrow disorders called myleoproliferative disease can be associated with increase platelets. ...Read more
One donor: This is a transfusion of platelets that are obtained from a single donor who is hooked to a machine that removes their platelets. The alternative is called random donor platelets and uses many bags of platelets that are separated out when a donor donates a unit of whole blood. ...Read more
Thanks for asking!:
There are 2 major processes associated with thrombocytosis (high platelet count), namely (1) essential or primary; (2) reactive or secondary.
Primary causes: essential thrombocytosis and other myeloproliferative disorders. Secondary causes include inflammation, surgery, hyposplenism (decreased platelet breakdown due to reduced function of the spleen), splenectomy, iron deficiency anemia, . ..Etc. ...Read more
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