Top
30
Doctor insights on: What Does Normal Tsh And High Thyroid Antibodies Mean

Share
1

1
What can cause high thyroid antibodies with normal tsh?

What can cause high thyroid antibodies with normal tsh?

Thyroid antibodies: Hashimotos disease - its an autoimmune disorder causing thyroid inflammation. An ultrasound should be performed to detect thyroid nodules. It can cause thyroid dysfunction ie TSH abnormalities over time. ...Read more

Dr. Melissa Haglund
71 doctors shared insights

Thyroid Antibodies (Definition)

Thyroid antibodies are autoantibodies that are found in 7% of the general population. They attack the thyroid. They are increased in hoshimoto's thyroiditis and 14% of patients with chronic idiopathic urticaria have ...Read more


2

2
Had high TSH (4.6). Refused Synthroid (thyroxine). Repeat test: Normal TSH (2.4), normal T4 (0.98), elevated T3 (4.8), negative thyroid antibodies. Any concerns?

Had high TSH (4.6). Refused Synthroid (thyroxine). Repeat test: Normal TSH (2.4), normal T4 (0.98), elevated T3 (4.8), negative thyroid antibodies. Any concerns?

No: Thyroid tests regularly fluctuate due to stress. My suggestion is to continue to keep an eye on it. May want to also have doctor examine ur thyroid and see if u need a UltraSound of the thyroid gland. ...Read more

3

3
Why and how can a person have high thyroid antibodies (hashimotos), hypothyroid symptoms but normal tsh, T3 (liothyronine) and t4? How does the body pull this off?

Why  and how can a person have high thyroid antibodies (hashimotos), hypothyroid symptoms but normal tsh, T3 (liothyronine) and t4? How does the body pull this off?

Thyroiditis: Antithyroid antibodies only suggest that there is an autoimmune reaction towards the thyroid. It takes a fair amount of destruction of the thyroid gland to affect its function. ...Read more

See 1 more doctor answer
4

4
Symptomatically hypothyroid patient with elevated thyroid antibodies but normal TSH, T4, and T3 (liothyronine). What is normally done in this situation?

Symptomatically hypothyroid patient with elevated thyroid antibodies but normal TSH, T4, and T3 (liothyronine).  What is normally done in this situation?

Usually you: follow the patient and institute BRAND NAME thyroid replacenebt when the TSH increases above nornal, TSH and free T4 are the only tests necessary once you have established elevated antithyroid ab's. Over 60% of normal people have soe symptoms of hypothyroid with a normal thyroid. Diseases can cause symptoms, but symptoms don't cause you to have a disease. ...Read more

5

5
Why is it not standard to do thyroid antibodies on someone with hypothyroid symptoms but a normal tsh?

Why is it not standard to do thyroid antibodies on someone with hypothyroid symptoms but a normal tsh?

May not be thyroid: Symptoms are often similar for a number of dieases. If symptoms suggest a certain disease a screening test will often be done. If the screening test is negative (TSH) further, more specific testing (thyroid antibodies) is usually not indicated. If symptoms persist with no other explanation, re-evaluation of a certain diagnosis may be indicated. ...Read more

See 1 more doctor answer
7

7
Do I need thyroid hormone if I have low free t3, (liothyronine) normal TSH and high tpo antibodies?

Do I need thyroid hormone if I have low free t3, (liothyronine) normal TSH and high tpo antibodies?

Possibly.: The TSH is normal so it might be a variation of normal or euthyroid. It also might be a developing thyroid condition, but there would be symptoms, like fatigue. The tpo antibodies might mean hashimoto's thyroiditis. This is usually associated with hypothyroidism. It would be wise to see your doctor to follow up. ...Read more

See 1 more doctor answer
8

8
Do i need treatment if my TSH 7.69 high normal free T4 and free T3 (liothyronine) and elevated thyroid antibodies?

Do i need  treatment if my TSH 7.69 high normal  free T4 and free T3 (liothyronine) and elevated thyroid antibodies?

Yes: Tsh 7.69 with high tpo is not "high normal" but high and indicates hypothyroidism. Having high tpo indicates autoimmune or hashimoto's thyroiditis. I suggest adding selenium zinc b complex and vitamin c and iodine and avoiding gluten for a month and rechecking levels in a month. If no change then you might need thyroid supplementation. ...Read more

See 1 more doctor answer
9

9
Thyroid antibodies are high, my free T4 low, TSH & free T3 (liothyronine) in normal range, on whole thyroid yet exp 2-4lb weight fluctuation & hair loss- what next?

Thyroid antibodies are high, my free T4 low, TSH & free T3 (liothyronine) in normal range, on whole thyroid yet exp 2-4lb weight fluctuation & hair loss- what next?

Imaging: If not done so, proper imaging of the thyroid is indicated, including ultrasound and nuclear thyroid uptake scan. You may be suffering from hashimoto's thyroiditis, an immunologic condition that affects your thyroid gland causing inflammation and often leads to an underactive thyroid gland (hypothyroidism). Hashimoto's disease is the most common cause of hypothyroidism in the United States. ...Read more

See 2 more doctor answers
11

11
If tpoab and tgab are present but within norm range what does that mean? Does everyone have positive thyroid antibodies? Fluctuating TSH as well.

Probably early : Thyroid disease. Autoimmune thyroid disease may present with just autoantibodies that you have. These are not normal. Your doctor likely plans to follow your TSH levels and if you develop any signs of thyroid deficiency, s/he will put you on medication. ...Read more

12

12
Sud a person wit thyroid antibodies +ve n TSH normal becum hypothyrod n future, my sis is already hypothyrod, any implications of vision problems frm it?

Sud a person wit thyroid antibodies +ve n TSH normal becum hypothyrod n future, my sis is already hypothyrod, any implications of vision problems frm it?

thyroiditis: A significant percentage of individuals with autoimmune antibodies to the thyroid gland develop hypothyroidism with time and need to have it corrected. If left uncorrected, a number of symptoms can occur, blurred vision is not a primary symptom but can occur. ...Read more

See 1 more doctor answer
13

13
I've had hypothryoid-like symptoms for a few years now. My TSH is normal but I have thyroid antibodies. Could it still be a thyroid issue?

Probably: The presence of thyroid antibodies makes you more likely to develop a thyroid problem which usually ended up with low thyroid status. Given the normal TSH however no treatment is indicated at this time. Just follow-up. ...Read more

15

15
6 months postpartum low TSH and thyroid antibodies found.Tsh went back to normal 2 months later. Hashimotos? Or just postpartum thyroiditis?

6 months postpartum low TSH and thyroid antibodies found.Tsh went back to normal 2 months later. Hashimotos? Or just  postpartum thyroiditis?

Probably: Postpartum, but doesn't really matter if lab returned to normal. It will obviously need to be monitored on an on-going basis as it could change in the future, particularly during a future pregnancy. ...Read more

16

16
My blood results came back normal but I still don't feel right? Tests for thyroid, antibodies, low test (TSH, T4, T3) and testicular. Physically

My blood results came back normal but I still don't feel right? Tests for thyroid, antibodies, low test (TSH, T4, T3) and testicular. Physically

Work with your team: When people just don't feel right in a general way, blood tests such as you had rarely give the answer. You need to find a provider (either MD or NP) who will listen to your complaints, get more history, and not just order tests. Perhaps you are not getting enough sleep or have some form of depression or mood disorder. Lots to consider and you need to see someone for more than 10-15 minutes ...Read more

17

17
Im 23yr female. Ive hypothyroid symptoms, but my T3, (liothyronine)T4,TSH test results came out normal. What thyroid tests should i take to test thyroid antibodies?

Im 23yr female. Ive hypothyroid symptoms, but my T3, (liothyronine)T4,TSH test results came out normal. What thyroid tests should i take to test thyroid antibodies?

Thyroid Ab's and...: Many people who are clinically hypothyroid have normal tests as what is normal is debatable. Many believe any TSH above 3 is too high, some even above 2. Check anti-thyroglobulin and TPO antibodies but also test Free T3 (liothyronine) and Reverse T3 (liothyronine). See http://tinyurl.com/koyamo5 and http://tinyurl.com/nrww2qg and http://www.stopthethyroidmadness.com/tsh-why-its-useless/ ...Read more

See 1 more doctor answer
19

19
I had normal tsh, t3, (liothyronine) t4, but antithyroglobulin antibody level is 263 and thyroid uptake showed homogenous uptake at 56%. What should I do?

I had normal tsh, t3, (liothyronine) t4, but antithyroglobulin antibody level is 263 and thyroid uptake showed homogenous uptake at 56%.  What should I do?

Auto immune thyroid: Your thyroid functions are normal presence of thyroglobulin antibodies indicate autoimmune disease though more sensitive test is tpo autoimmune disease makes thyroid inefficient and hence iodine trapppping is increased of these people 30 percent will develop undersctivity. ...Read more

20

20
Suppressed TSH 0.02 for about two,months that I know of. Free T3 (liothyronine) and T4 Normal. Thyroid antibodies Normal. Thyroid ultrasound normal? Confused?help!

Suppressed TSH 0.02 for about two,months that I know of. Free T3 (liothyronine) and T4 Normal. Thyroid antibodies Normal. Thyroid ultrasound normal? Confused?help!

2 possibilities: Hi. This could still be a phase of a subacute thyroiditis, although the window of time on that possibility is closing. The other is one or more autonomously hyper-functioning nodules, which in NOT ruled out by your ultrasound. An 123-Iodine uptakes and scan would clarify the issue: VERY low uptakes in subacute thyroiditis, and normal uptakes with hot spot(s) on scan image in toxic nodule(s). ...Read more

21

21
Positive thyroid antibodies, a TSH of .5, normal T3 (liothyronine) and normal T4. My mother has Hashimotos. I have hypothyroid symptoms. Dr wont help me. help!

Positive thyroid antibodies, a TSH of .5, normal T3 (liothyronine) and normal T4. My mother has Hashimotos. I have hypothyroid symptoms. Dr wont help me. help!

Well...: fortunately your thyroid function test are normal! They should be checked about every year Realize, that symptoms of hypothyroidism are similar to depression, or other diseases. You may want to have a serious conversation with your Dr. or get another one ...Read more

See 1 more doctor answer
22

22
Thyroid swelling. Ultrasound heterogenous thyroid parynchema with hypervascularity. Blood test-normal tsh t4 t3 (liothyronine) etc but >1300 TPo antibodies?

Thyroid swelling. Ultrasound heterogenous thyroid parynchema with hypervascularity. Blood test-normal tsh t4 t3 (liothyronine) etc but >1300 TPo antibodies?

Hard to say: Ive yet to have anyone NOT have elevated TPo but I havent sent many. The standard answer would be that it likley is GRAVES disease starting but if there arent a lot of symptoms and the labs are normal you wouldnt give treatment. Retesting if symptoms and at about every 3 months. ...Read more

See 1 more doctor answer
23

23
Thyroid Ultrasound heterogenous thyroid parynchema with hypervascularity. Blood test normal tsh t4 t3 (liothyronine) etc but >1300 TPo antibodies?have Hypo symptoms

Thyroid Ultrasound heterogenous thyroid parynchema with hypervascularity. Blood test normal tsh t4 t3 (liothyronine) etc but >1300 TPo antibodies?have Hypo symptoms

Elevated: TPO levels are associated with autoimmune thryroid disease/thryoiditis, for example Hashimoto disease. The thyroid US findings are also consistent with thyroiditis. Talk to your doc about next steps. ...Read more

24

24
My TSH levels are 4.67.I am on 25mcg levothyroxin.Doc said its hashimoto's.Should I ask to check my thyroid antibodies too?or the treatment is same?

Same treatment: If you are/were hypothyroid and are doing well on replacement medication, knowing the status of your auto-antibodies is not going to change the course of treatment. ...Read more

25

25
My TSH fluctuates goes to 5.5 with 12.5 mcg comes down to .27 on 25mcg. anti thyroid antibodies +ve. how to titrate.only hair loss no hypothyroid symp?

Dosing: Hi. Most systems are not that sensitive! I would suggest trying 12.5 mcg on even days of the month and 25 mcg on odd days of the mont. This will give you an average daily dose of 18.75 mcg, and should give you a nice, normal TSH. But to reiterate, most systems are not that sensitive. Make sure you're well equilibrated (dose at least 6 weeks) before testing. Good luck! ...Read more

26

26
Low free t3, (liothyronine) normal TSH and high tpo antibodies. What's this mean?

Low free t3, (liothyronine) normal TSH and high tpo antibodies. What's this mean?

Probable hypothyroid: The free t4, not free T3 (liothyronine) test, is necessary here. Positive antibodies indicate hashimoto's thyroiditis, the most common cause of hypothyroidism. It may just be early in the process to cause the TSH to be elevated. ...Read more

27

27
What does it mean when someone, who has never taken any thyroid meds, has at times high TSH (5.6 uIU/ml) and at times normal TSH (2.6 uIU/ml)?

What does it mean when someone, who has never taken any thyroid meds, has at times high TSH (5.6 uIU/ml) and at times normal TSH (2.6 uIU/ml)?

Signals: TSH is a signal produced by the pituitary for the thyroid to make more hormone. It is based on a regulation system in which thyroid levels are monitored. Depending on stress, environmental, and other factors your thyroid levels may fluctuate. This explains why the TSH levels can fluctuate with it. Try to focus more on symptoms than a lab result. ...Read more

See 1 more doctor answer
28

28
I have hashimotos disease normal TSH and norml t 3 and T4 , but high antibodies , do I need medication?

Not yet: You will likely need thyroid pill in the future as the disease progresses but not yet. This condition needs to be followed by your doctor regularly. ...Read more

See 2 more doctor answers
29

29
What is the meaning of high level of anti-TPO antibodies but normal TSH and t4?

Hashimoto's thyroid : It means you have hashimoto's thyroid disease but your thyroid function is currently normal. This might be because you are taking the correct dose of thyroid hormone replacement or because your thyroid is still able to make normal amount of hormone despite the insults from the antibodies. If this is the case, monitor your thyroid function closely because you will become hypothyroid in the future. ...Read more

30

30
Tests show I have a normal tsh, T3 (liothyronine) but low T4 & free T4 and antibody of .7 what do these results mean?

Tests show I have a normal tsh, T3 (liothyronine) but low T4 & free T4 and antibody of .7 what do these results mean?

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. It would help to know the actual values of all the hormones. ...Read more

Dr. Quang Nguyen
923 doctors shared insights

Thyroid Stimulating Hormone (Definition)

A TSH test measures the amount of thyroid stimulating hormone (TSH) in your blood. TSH is produced by the pituitary gland and tells the thyroid gland to make and release the hormones thyroxine ...Read more


Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more