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Doctor insights on: What Does Low Ig M Level Mean

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what is difference between IgM and IgG for western blot for lyme. positive for IgM but not IgG, what does that mean? tks

what is difference between IgM and IgG for western blot for lyme. positive for IgM but not IgG, what does that mean? tks

Recent infection: Hi. IgM is present only with recent infection. After IgM levels fall away, IgG takes over for ongoing and recurrent exposure to antigen. (The antibodies in this picture are IgG's). I'm glad your doc was on the ball. She/he may have saved you a world of hurt by making the diagnosis promptly. Good luck! ...Read more

Dr. Gregory Lanza
816 doctors shared insights

Immunoglobulin M (Definition)

There are 5 classes of immune proteins: igg, iga, igm, ige and igd. Igm fights infection. If you produce too little then infections may occur and you have hypogammaglobulinemia. If you have too much you ...Read more


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What does low level of IgM mean?

What does low level of IgM mean?

Maybe nothing?: Igm is a type of antibody you make to help fight infections. Slightly low igm by itself may not mean anything (i.e., your nature level). If it is very low, or other antibodies are also low (or not functioning), it may be a sign of immune deficiency that can lead to more infections. If you have ?S, see a clinical immunologist. They can help determine if your immune system is functioning properly. ...Read more

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What does it mean to have a low IgM level?

What does it mean to have a low IgM level?

Immune test: The body normally makes immunoglobulins iga, igg, igm, ige and igd. Low or absent IG levels are seen in patients with recurrent infections. A low igm level that is clinically relevant usually occurs in the presence of a low igg and/or IgA level. It is always best to treat a patient, not a number. If a person is otherwise healthy and only has lower igm, usually no worries. ...Read more

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What does it mean that I have a low IgM level?

What does it mean that I have a low IgM level?

Low IgM: Low IgM levels in and of themselves are not common, but can occur. If they occur with low IgG levels or with other clinical symptoms the diagnosis can be different. Isolated low IgM can be caused by a variety of factors, and often eventually resolves. See an immunologist for further evaluation to determine the cause. ...Read more

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What do elevated levels of IgM mean?

Depends: The "normal ranges" for all lab tests include 95% of the "normal" population; thus, 2.5% of people are above the upper limit, and 2.5% are below the lower limit. There's nothing to worry about if your values are a little bit above the normal range, but a very elevated IgM could be a sign of a problem. You need to check with the physician who ordered the tests to interpret your results. ...Read more

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What does it mean if IgM and IgA levels drop lower?

What does it mean if IgM and IgA levels drop lower?

IgM and IgA: Low levels of IgA and IgM may mean that you have an immune deficiency. If they are only slightly low and your igg is normal and you are able to respond to vaccines and do not have a lot of infections, there may be nothing to worry about. We need a lot of history and additional blood tests to understand what any particular level of antibodies in the blood means. ...Read more

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What could it mean if IgM and IgA levels drop lower after being rechecked?

What could it mean if IgM and IgA levels drop lower after being rechecked?

IgA, IgM: Were they low to start with? Did you attemt to treat them? Some variation is testing as well as the body is normal. Should be same lab, same method, similar results. ...Read more

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My son has low IgM and high white cells. Everything else is normal. What does this mean?

My son has low IgM and high white cells. Everything else is normal. What does this mean?

High white cell?: Low IgM per se is unlikely to be of major clinical importance but a persistently high WBC requires further evaluation by a hematologist in the absence of an acute or chronic infection. On the other hand, a transiently elevated WBC (no more than a week duration) is likely from an acute infection be it viral or bacterial. ...Read more

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My IgM levels are very low all the others are on the low side but not excessively I have suffered ill health since childhood can you shed any light?

My IgM levels are very low all the others are on the low side but not excessively I have suffered ill health since childhood can you shed any light?

Not significant?: Good morning, low levels of igm by itself may not be significant. However, you have had health problems since childhood. There is a condition known as selective igm deficiency in which there is an absence of igm and normal levels of igg and iga. Igm does play a role in fighting infection as it is the first antibody produced in an acute infection. About 2.5% of people have lower than normal igm lev. ...Read more