Top
20
Doctor insights on: What Does Low Ig M Level Mean

Share
1

1
what is difference between IgM and IgG for western blot for lyme. positive for IgM but not IgG, what does that mean? tks

what is difference between IgM and IgG for western blot for lyme. positive for IgM but not IgG, what does that mean? tks

Recent infection: Hi. IgM is present only with recent infection. After IgM levels fall away, IgG takes over for ongoing and recurrent exposure to antigen. (The antibodies in this picture are IgG's). I'm glad your doc was on the ball. She/he may have saved you a world of hurt by making the diagnosis promptly. Good luck! ...Read more

Dr. Gregory Lanza
816 doctors shared insights

Immunoglobulin M (Definition)

There are 5 classes of immune proteins: igg, iga, igm, ige and igd. Igm fights infection. If you produce too little then infections may occur and you have hypogammaglobulinemia. If you have too much you ...Read more


2

2
What does low level of IgM mean?

What does low level of IgM mean?

Maybe nothing?: Igm is a type of antibody you make to help fight infections. Slightly low igm by itself may not mean anything (i.e., your nature level). If it is very low, or other antibodies are also low (or not functioning), it may be a sign of immune deficiency that can lead to more infections. If you have ?S, see a clinical immunologist. They can help determine if your immune system is functioning properly. ...Read more

3

3
What does it mean to have a low IgM level?

What does it mean to have a low IgM level?

Immune test: The body normally makes immunoglobulins iga, igg, igm, ige and igd. Low or absent IG levels are seen in patients with recurrent infections. A low igm level that is clinically relevant usually occurs in the presence of a low igg and/or IgA level. It is always best to treat a patient, not a number. If a person is otherwise healthy and only has lower igm, usually no worries. ...Read more

4

4
What does it mean that I have a low IgM level?

What does it mean that I have a low IgM level?

Low IgM: Low IgM levels in and of themselves are not common, but can occur. If they occur with low IgG levels or with other clinical symptoms the diagnosis can be different. Isolated low IgM can be caused by a variety of factors, and often eventually resolves. See an immunologist for further evaluation to determine the cause. ...Read more

See 1 more doctor answer
6

6
What do elevated levels of IgM mean?

Depends: The "normal ranges" for all lab tests include 95% of the "normal" population; thus, 2.5% of people are above the upper limit, and 2.5% are below the lower limit. There's nothing to worry about if your values are a little bit above the normal range, but a very elevated IgM could be a sign of a problem. You need to check with the physician who ordered the tests to interpret your results. ...Read more

7

7
What does it mean if IgM and IgA levels drop lower?

What does it mean if IgM and IgA levels drop lower?

IgM and IgA: Low levels of IgA and IgM may mean that you have an immune deficiency. If they are only slightly low and your igg is normal and you are able to respond to vaccines and do not have a lot of infections, there may be nothing to worry about. We need a lot of history and additional blood tests to understand what any particular level of antibodies in the blood means. ...Read more

8

8
What could it mean if IgM and IgA levels drop lower after being rechecked?

What could it mean if IgM and IgA levels drop lower after being rechecked?

IgA, IgM: Were they low to start with? Did you attemt to treat them? Some variation is testing as well as the body is normal. Should be same lab, same method, similar results. ...Read more

9

9
My son has low IgM and high white cells. Everything else is normal. What does this mean?

My son has low IgM and high white cells. Everything else is normal. What does this mean?

High white cell?: Low IgM per se is unlikely to be of major clinical importance but a persistently high WBC requires further evaluation by a hematologist in the absence of an acute or chronic infection. On the other hand, a transiently elevated WBC (no more than a week duration) is likely from an acute infection be it viral or bacterial. ...Read more

10

10
My IgM levels are very low all the others are on the low side but not excessively I have suffered ill health since childhood can you shed any light?

My IgM levels are very low all the others are on the low side but not excessively I have suffered ill health since childhood can you shed any light?

Not significant?: Good morning, low levels of igm by itself may not be significant. However, you have had health problems since childhood. There is a condition known as selective igm deficiency in which there is an absence of igm and normal levels of igg and iga. Igm does play a role in fighting infection as it is the first antibody produced in an acute infection. About 2.5% of people have lower than normal igm lev. ...Read more

11

11
What could elevated levels of IgM in a blood test mean?

What could elevated levels of IgM in a blood test mean?

IgM specific: Antibody. Elevated levels of IgM are non-specific, but elevated levels of IgM antibody specific to a bug usually means recent infection with that particular organism. ...Read more

12

12
My IgM level went from normal to very low. Down to 28. What is going on? I am being followed for biclonal gammopathy. Should I worry

Keep Following: There are a number of variables which could be contributing to this and for the sake of brevity (i'm only allowed a 400 letter answer) i suggest that you keep your appointments with your specialist. ...Read more

See 1 more doctor answer
13

13
My Igm level has been in the 700 range for over a year. bloodwork is currently 744 and my MCHC levels are low. 31.8. Is there a correlation? Thoughts

My Igm level has been in the 700 range for over a year. bloodwork  is currently 744 and my MCHC levels are low. 31.8. Is there a correlation? Thoughts

Monoclonal?: First you need to find out if the IgM is monoclonal or polyclonal. Then you need to tell us what kinds of symptoms you have besides a low MCHC which is more likely associated with iron deficiency in your age group. Then let's talk again. ...Read more

14

14
What is the significance of low Igm levels in smoldering Multiple Myeloma?

What is the significance of low Igm levels in smoldering Multiple Myeloma?

Depends: If you have M protein from another class of immunoglobulin, then the cells producing this M protein would crowd out the other immunoglobulin producing cells in the bone marrow leading to a lower level of what that cell would ordinarily produce. Some Multiple myeloma cases are of no medical significance but needs to be followed. Many myeloma patients are prone to bacterial infections. ...Read more

15

15
What is the significance of a low Igm level in smoldering multiple myeloma?

Part of the disease: Whenever you have smoldering myeloma of certain type, say IgG for example, the other antibody types like IgM and IgA are often decreased. It is just part of the disease process to see a paradoxical lower of other antibody types that are not involved in smoldering myeloma. ...Read more

16

16
A recent blood test showed an IgM level of 492. I have no idea what this means?

A recent blood test showed an IgM level of 492. I have no idea what this means?

Consult your doctor: Normal IgM levels are about 50-250 mg/dl. A level of 492 does not necessarily mean a disease, but you should consult the doctor who ordered the test so that it may interpreted in the context of your history and other findings. ...Read more

17

17
Should a low level of serum IgM (26) for an adult that is asymptomatic be followed up with other diagnostic tests and if so, which ones?

Should a low level of serum IgM (26) for an adult that is asymptomatic be followed up with other diagnostic tests and if so, which ones?

IgM: Normal ranges for IgM can be challenging since this is the "first" antibody that appears, but also one that fades quickly. Neoplasms that make IgM are a bigger concern in an otherwise healthy adult. So, to answer your question, No, I would not recommend you either worry about a below "normal" result nor that you follow it up. Be grateful that it is not high. ...Read more

18

18
My 18 month old son has low IgA and igm. Normal igg. What does this mean? He's had repeat bloods and they were still low.

My  18 month old son has low IgA and igm. Normal igg. What does this mean? He's had repeat bloods and they were still low.

Important point: Is why were they measured? His body has shown that his immunity is affected. The only way that you can upgrade it is by the art and science of good nutrition. That is actually the only way. Hinppocrates said "let food be your medicine and your medicine be your food" that was 400 bce and the rule still holds today because we have the same biology as they did in his era. ...Read more

19

19
My 2yr son has been doing infusion treatment for over a yr now for.low IgG and his IgM is still very low what does thar mean?

My 2yr son has been doing infusion treatment for over a yr now for.low IgG and his IgM is still very low what does thar mean?

Trace IgM: Most immune globulin infusions primarily contain IgG with only trace amounts of IgA and IgM. Typically we monitor only IgG peak and trough levels. ...Read more

See 2 more doctor answers