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Doctor insights on: What Does It Mean When Ovarian Insufficiency

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Dr. Michael Opsahl
26 doctors shared insights

Ovarian Insufficiency (Definition)

Ovarian insufficiency, also called premature ovarian failure, is a condition like menopause but occurs before the age of 40 and consists of infertility, loss of menstrual periods, hot ...Read more


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What are the symptoms of ovarian insufficiency?

What are the symptoms of ovarian insufficiency?

Irregular/ no period: Irregular cycles or no periods, especially in a woman who was regular before, is a common sign. However there are many other causes of irregular cycles that we need to exclude. Hot flashes, vaginal dryness, or mood changes may occur, particularly if the woman's periods are stopped. Some women with primary ovarian insufficiency still have regular periods but see md for difficulty getting pregnant. ...Read more

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What is the treatment for ovarian insufficiency?

What is the treatment for ovarian insufficiency?

Trying to conceive?: If not trying to conceive: bone density scan, calcium, vitamin d, and hormone replacement with estrogen and progestin. We look for and treat any adrenal insufficiency. If you're trying to conceive, 5-10% of women with poi will get pregnant on their own after diagnosis, but if you truly have poi we don't have good fertility treatments using your own eggs. Egg donation or embryo donation are best. ...Read more

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What are the tests for primary ovarian insufficiency?

What are the tests for primary ovarian insufficiency?

Many tests, see REI: Reproductive endocrinology md will confirm poi - pregnancy test, fsh, lh, estradiol, amh, thyroid and prolactin tests, pelvic ultrasound. Test for genetic causes: karyotype looking for turner's syndrome, fragile x premutation testing, fish test for sry (y-chromosome material). Test adrenal antibodies which cause addison's disease. Screen for diabetes, thyroid antibodies, and parathyroid disease. ...Read more

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What are the symptoms associated with primary ovarian insufficiency?

What are the symptoms associated with primary ovarian insufficiency?

Irregular/ no period: Irregular cycles or no periods, especially in a woman who was regular before, is a common sign. However there are many other causes of irregular cycles that we need to exclude. Hot flashes, vaginal dryness, or mood changes may occur, particularly if the woman's periods are stopped. Some women with primary ovarian insufficiency still have regular periods but see md for difficulty getting pregnant. ...Read more

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Was planning to see classmates at upcoming 20th reunion. Now I am hearing my best friend has ovarian insufficiency. What is that?

Premature menopause: Ovarian insufficiency is another way of saying someone is going through menopause. There can be various causes of why someone might go through this prematurely. This can be treated with supplemental hormones and should not keep your friend from attending the reunion. ...Read more

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What is the treatment for primary ovarian insufficiency?

What is the treatment for primary ovarian insufficiency?

Trying to conceive?: If not trying to conceive: bone density scan, calcium, vitamin d, and hormone replacement with estrogen and progestin. We look for and treat any adrenal insufficiency. If you're trying to conceive, 5-10% of women with poi will get pregnant on their own after diagnosis, but if you truly have poi we don't have good fertility treatments using your own eggs. Egg donation or embryo donation are best. ...Read more

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Is there something wrong with ovaries or hormone system if I have ovarian insufficiency?

Is there something wrong with ovaries or hormone system if I have ovarian insufficiency?

EARLY menopause: Ovarian failure or 'insufficiency' is a really another name for menopause (which may be premature if <40 yo). Normally the pituitary gland (in the brain) sends 2 hormone messengers FSH & lh to 'tell' the ovary to make estrogen/'female' hormones. When the ovary 'fails' =estrogen levels drop and fsh/lh levels rise confirming ovarian 'insufficiency' . Treatment with 'hormones' is optional. ...Read more