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Doctor insights on: What Does It Mean If Your Globulin Is Low

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What does having low globulin levels mean and how can I get it to normal?

What does having low globulin levels mean and how can I get it to normal?

Be more specific: There are lots of globulins & to answer your question we need to know the type and reason the test was done. People have a range of antibody levels, globulins in certain classes, IgA, IgG, Ig E, or specific globulins to a prior illness or vaccinations. Without knowing specifics we cannot provide a specific answer. You are welcome to start over. Posts are not linked so each must have all info. ...Read more

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If your albinum level is low does that mean your globulins level and protein will elevate.

If your albinum level is low does that mean your globulins level and protein will elevate.

Not necessarily: It would depend on why the albumin is low.
All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Talk to the doctor who ordered the tests.
Wish you good health! - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex, if you have sex.
Get HPV vaccine ...Read more

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What could a high immunoglobulin g 1660 and low a1 globulin 1.9 & a2 globulin 10.6 mean?

What could a high immunoglobulin g 1660 and low a1 globulin 1.9 & a2 globulin 10.6 mean?

IgA Deficiency: Sounds like selective IgA deficiency, if these are the results. Selective IgA deficiency is the most common immunodeficiency in the world and is usually benign but needs to be followed. IgA def in women is more significant since it can convert to common variable immune deficiency and there is HUGE risk of lymphoma development in the 50's-60's. See an immunologist ...Read more

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Low globulin, high albumin/globulin, high ALT what does it mean?

Low globulin, high albumin/globulin, high ALT what does it mean?

Need more info: Lab test results need to be interpreted in the clinical context and is best done by the doctor who ordered the test as s/he likely knows your health history. A doctor needs to know the actual values of the results and more clinical information. ...Read more

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Hello. My blood work shows slightly Low Globulin and High Alanine 2.1 low and 49 high What could this mean?

Hello.  My blood work shows slightly Low Globulin and High Alanine 2.1 low and 49 high What could this mean?

Incomplete info: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, the information your provided does not add up. It would be prudent to discuss it with the doctor who ordered the tests.
For good health — Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex.
Get HPV vaccine. ...Read more

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What does it mean to have low alk phos levels and ALT levels globulin low and could there be something underlying?

What does it mean to have low alk phos levels and ALT levels globulin low and could there be something underlying?

Not concerning. : There is generally no significance to low levels of ast or alkaline phosphatase. In a healthy pt it is very unlikely that low globulin is of any concern. ...Read more

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What does it mean if my testosterone is normal but I have a low level of sex hormone binding globulin?

What does it mean if my testosterone is normal but I have a low level of sex hormone binding globulin?

Free Testosterone: Hi. If your total testosterone is normal and you have low SHBG, you have a plenty normal free testosterone. Therefore, you're eugonadal (normal pituitary and gonadal function). ...Read more

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My monocytes and eosinophils high and my neutrophils low. What does this mean? Also, why is my total protein and globulin high?

My monocytes and eosinophils high and my neutrophils low. What does this mean? Also, why is my total protein and globulin high?

Need values: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, it would have helped to have the actual values rather your interpretation of high and low. ...Read more

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1yr has h 2.8 a/g ratio, h 128 alt(sgpt), h <70 bum/create ratio, l 19 co2, l 1.4 globulin, h 33 ige, l 171 igg, h 11 mono% what does this mean? H=high l=low

1yr has h 2.8 a/g ratio, h 128 alt(sgpt), h <70 bum/create ratio, l 19 co2, l 1.4 globulin, h 33 ige, l 171 igg, h 11 mono% what does this mean? H=high l=low

Clinical context: All lab results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. There are different normal ranges for babies and the h/l marks are likely based on adult values. Please discuss the matter with your pediatrician. ...Read more

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Pathology — prostaglandin e2 serum came 534 high and alpha 1 globulin came .4 high. McCoy came 80fl low and hematocrit 38% what's hat mean?

Pathology — prostaglandin e2 serum came 534 high and alpha 1 globulin came .4 high.  McCoy came 80fl low and hematocrit 38% what's hat mean?

Not much: Alpha 1 is mostly antitrypsin which is an acute phase reactant and if elevated it means nothing really. Prostaglandin E2 is not a routine piece of lab work. The 'city is okay for a guy. If by McCoy you mean MCV / mean corpuscular volume, 80 fL is okay with me as a pathologist. Relax and be glad for okay labs. ...Read more

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What does it mean if I am a female, have normal estrogen, testosterone & TSH, but low sex hormone binding globulin?

What does it mean if I am a female, have normal estrogen, testosterone & TSH, but low sex hormone binding globulin?

Nothing - u r normal: Regardless of gender, if your estrogen, testosterone & TSH are normal, then you're normal. Sex hormone binding globulin is used to bind up sex hormones, exactly what it says. Sometimes we check both total hormone and free hormone, since it's typically free hormone that accounts for benefit claimed by hormone. But rather than look at numbers, consider how you feel. We treat patients, not #s. ...Read more

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Total ck, sed rate, ana, ip ace, serum protein panel normal but gamma globulin (.6) cortisol am (30.8) Hx of low vit d and K. What could this mean?

Total ck, sed rate, ana, ip ace, serum protein panel normal but gamma globulin (.6) cortisol am (30.8)
Hx of low vit d and K. What could this mean?

Not much-: An important thing to remember is that lab results are not useful unless there is a clinical context. Advice is based on focusing on the patient, not the numbers. Though you mention a history of low vit D and K, did symptoms exist when the labs were drawn? Why were they drawn in the first place? Otherwise, it is best to ask your ordering doctor what the results mean. ...Read more

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What does polyclonal increase in gamma globulin levels mean?

What does polyclonal increase in gamma globulin levels mean?

Great: Polyclonal is good it means yo are eating very well -protein should however check your cholesterol. ...Read more

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What does an elevated igg and gamma globulin mean? Years ago I had an elevated epv igg as well.

Depends: On how high it is and whether it is "monoclonal* or not. A value even up to 20-30% higher than predicted usually means nothing in the absence of disease. ...Read more

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Does anyone know what a huge drop in globulin means and what could cause ankylosing sponditilits?

Does anyone know what a huge drop in globulin means and what could cause ankylosing sponditilits?

Depends: It's hard to know what you mean by a huge drop. Some medications can drop the globulins such as immunosuppressants. The cause may be outside the ankylosing spondylitis. Please see you health care provider about this. ...Read more

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In my case I have low globulin 1.8 and high a/g ratio. I definately fasted prior. I'm a 31-year-old female. Healthy. I do try to eat a lot of protein?

In my case I have low globulin 1.8 and high a/g ratio.  I definately fasted prior. I'm a 31-year-old female.  Healthy. I do try to eat a lot of protein?

Insufficient info: Globulins consist of a number of different proteins, and you need a serum protein electrophoresis, as a start, for a detailed examination of the different proteins. Please consult the doctor who ordered the test. ...Read more

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Low auto lymph high globulin low a/G RATIO?

Low auto lymph high globulin low a/G RATIO?

A/G ratio: If you are referring to a low albumin to globulin ratio, this lab parameter only has significance when taken into context with the information gathered by the doctor from history, physical, and other labs. A low A/G ratio ( ...Read more

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What causes high globulin, but low globulin albumin ratio?

What causes high globulin, but low globulin albumin ratio?

Liver blood tests: The liver is an amazing organ- it does many things including making proteins your body needs. Albumin is a major protein product of the liver. Chronic illness can cause that to decline- esp. if you're not eating. Globulins are other proteins usually made to fight diseases like infections- perhaps you've been fighting an illness for a few weeks/months that explain this pattern. ...Read more

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What does it mean by gamma globulin 2.2? Means early cancer?

What does it mean by gamma globulin 2.2? Means early cancer?

Gamma globulin has: No relation to cancer. A "gamma spike" may implicate over production of an abnormal protein in bone/marrow "cancer" called myeloma. ...Read more

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What does it mean when protein syrum Beta 2 Globulin are high with beta gamma bridging?

Need more info: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, the pattern could be due to liver disease, chronic inflammation in the intestine or neoplastic proliferation of plasma cells. Discuss it with the doctor who ordered the test. ...Read more

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What can cause low serum globulin, 1.5 (reference cutoff 1.6)? Can slightly low globulin have an effect the accuracy of other labs?

May not be anything.: It's not clear if such a small reduction means anything. Globulin on a chemistry panel measures a group of blood proteins that include antibodies. A low globulin can mean lowered immunity, but not always. Additional testing (quantitative immunoglobulins) should be done to verify normal immune function. ...Read more

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Globulin 2.0 L And alb/glob 2.4 H what does this mean and should it be repeated? Mall other blood work great! Could this be leukemia? Just concerned.

Globulin 2.0 L And alb/glob 2.4 H what does this mean and should it be repeated? Mall other blood work great! Could this be leukemia? Just concerned.

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, the information you provided is not a cause for concern. There is nothing the data provided to suggest leukemia. ...Read more

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My g-globulin is 0.7 where norm is 0.7 to 1.7. Also, ANA titter is 1:320 diffuse #. What do those two statements mean. I have been diagnosed scleritis?

My g-globulin is 0.7 where norm is 0.7 to 1.7. Also, ANA titter is 1:320 diffuse #. What do those two statements mean. I have been diagnosed scleritis?

Can be many things,,: These can mean many things. The low gamma globulins might mean hypogammaglobulinemia from their being used up in immune reactions and the ANA titer is high and indicates some possible autoimmune process going on as does your scleritis. The "diffuse" pattern can be synonymous with "homogenous" meaning anti-dsdna pointing to lupus, but more tests and symptoms may be needed for dx. Good luck. ...Read more

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Y total portin 8.2 normal to 8.3 albumin 3.8 and normal to 4.8 mean globulin is high could it be to multiple myeloma?

Y total portin 8.2 normal to 8.3 albumin 3.8 and normal to 4.8 mean globulin is high could it be to multiple myeloma?

Not necessarily: In most cases of elevated globulin, no multiple myeloma is present. Globulin elevation is often non-specific and can be present in cases of inflammation such as colds, infections, etc. To rule in multiple myeloma, there must be certain globulin fractions present. Electrophoresis of the blood and/or urine will be able to determine that. ...Read more

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Y albumin 3.9 and the normal range for albumin is 4.8 at my lab so it mean that globulin level is high so could it be high because multiple meanloma?

Y albumin 3.9 and the normal range for albumin is 4.8 at my lab so it mean that globulin level is high so could it be high because multiple meanloma?

Not likely: You can not tell that you have increased globulin by Albumin alone, you will need a total protein to see that.

18 year olds very very rarely have myeloma. This Albumin is not so low, check both labs again and stop worrying. ...Read more

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Mytotal portin 8.2 normal to 8.3albumin3.8and normal to 4.8 mean globulin is 4.4 could it be to multiple myeloma? Tot ca is 9.2, ion ca is 1.15 ESR 12

Mytotal portin 8.2 normal to 8.3albumin3.8and normal to 4.8 mean globulin is 4.4 could it be to multiple myeloma? Tot ca is 9.2, ion ca is 1.15 ESR 12

No reason: Myeloma is a disease of older patients that causes bone problems, anemia, kidney disease and high calcium. Those few blood tests look ok, including the calcium, so i don't know why you are thinking about myeloma. ...Read more