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Doctor insights on: What Does It Mean If Tsh Is High

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My free T4 is high 19.30 pmol/l and my TSH is also high 4.530 mlu/l. What does this mean?

My free T4 is high 19.30 pmol/l and my TSH is also high 4.530 mlu/l.  What does this mean?

Few possibilities: These labs seem at odds, with TSH suggesting overactive thyroid and ft4 underactive thyroid. Free T4 tests can be inaccurate in some people who have interfering substances present. Another possibility is a tumor in the pituitary secreting too much TSH resulting in thyroid overactivity, and high thyroid hormone levels. This is quite rare, however. Your doctor can help sort this out. ...Read more

Dr. Quang Nguyen
923 doctors shared insights

Thyroid Stimulating Hormone (Definition)

A TSH test measures the amount of thyroid stimulating hormone (TSH) in your blood. TSH is produced by the pituitary gland and tells the thyroid gland to make and release the hormones thyroxine ...Read more


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What does it mean to have a high tsh reading of 16.8 and a high ft4 of 8.2 What condition does this indicate?

What does it mean to have a high tsh reading of 16.8 and a high ft4 of 8.2   What condition does this indicate?

16.8 and 8.2: This is an uncommon observation but suggests that your TSH is pushing up your T4 and imaging of your TSH site is essential. Once the cause is found appropriate care should be OK. Please let me know what your doctors find. ...Read more

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What does it mean if I have high tsh, t3, (liothyronine) T4 levels?

What does it mean if I have high tsh, t3, (liothyronine) T4 levels?

HiTSH=hypo,hiT4 hype: Thyroid function is measured many ways. The TSH is your body's call for more hormone, so a high TSH suggests underactive thyroid, very low TSH overactive. The t4/t3 levels are measures of circulating hormone, so high T4 or T3 (liothyronine) suggest hyperthyroidism and vice versa. T4 levels can beaffected by hormones and so need to be interpreted carefully. For initial testing, the TSH alone best test. ...Read more

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What does it mean if TSH is 0, but T3 (liothyronine) and/or T4 are elevated?

What does it mean if TSH is 0, but T3 (liothyronine) and/or T4 are elevated?

Hyperthyroidism: If a third generation test was use to measure TSH you likely have hyperthyroidism and should your doctor as soon as possible. See this site for more info. http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0001396/. ...Read more

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My TSH 3rd generation test came back at 2.036. The range is 0.340-5.600uiu/m. The test said high sensitive 3rd generation tsh. What does this mean?

My TSH 3rd generation test came back at 2.036. The range is 0.340-5.600uiu/m. The test said high sensitive 3rd generation tsh. What does this mean?

Not a whole lot!: An elevated TSH is the main criteria most docs use to diagnose hypothyroidism. While most docs feel it is not abnormal unless above 5.6 or so, many endocrinologists feel anything above 3 is abnormal, and some even feel a level above 2 could indicate problems- see http://abt.Cm/1562fwq actually, many with a totally normal TSH may still have thyroid problems- see http://bit.Ly/18atkro & comment:. ...Read more

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My TSH is normal and T4 is high? What does that mean?

My TSH is normal and T4 is high?  What does that mean?

How high? Free T4: Total T4 depends on thyroid binding globulins and may be elevated in pregnancy, contraceptive pill intake etc. If TSH is normal and you do not have any symptoms, you can leave it alone. At your next visit with your doctor you may discuss getting free T4 and T3 (liothyronine) done for confirmation of normal status. ...Read more

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High TSH levels but normal T4 levels, i don't understand what this means?

High TSH levels but normal T4 levels, i don't understand what this means?

Early hypothyroidism: If the elevated TSH persists, it generally indicates early hypothyroidism, which can easily be diagnosed and treated by your doctor. ...Read more

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I have a high TSH but normal T4 levels, what does this mean?

I have a high TSH but normal T4 levels, what does this mean?

Hypothyroidism: The TSH test is10 times more sensitive for the diagnosis of hypothyroidism that the t4. The TSH is reported on a log scale so that small changes in the TSH value are caused by relatively big changes in the blood level. This is a reflection of the pituitary being extremely sensitive to change in the T3 (liothyronine) level if you have symptoms it would be wise to seek treatment. ...Read more

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Tsh high/ egfr low & slight hemolysis, what does all this mean?

Tsh high/ egfr low & slight hemolysis, what does all this mean?

Low thyroid : A high TSH almost always means that there is too little thyroid hormone in the blood. It would not usually cause decreased kidney function as suggested by a low egfr (estimated glomerular filtration rate) or breakdown of red blood cells (hemolysis). The hemolysis and decreased kidney function might be related however. Your situation is and complex and potentially serious - see your doctor! ...Read more

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What does a tsh, high sensitivity level of 177.70 mean for a male patient?

Thyroid deficiency: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, If you are using conventional units for TSH, this level indicates severe deficiency of thyroid function. See this site for more info. https://www.nlm.nih.gov/medlineplus/ency/article/003684.htm ...Read more

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Does it allways mean that high prolactin=40ng/ml and tsh=5.04yu/ml cause infetility?

No: No it doesn't, but both can hinder your normal fertility. Fasting prolactin shouldn't usually be above around 20-25 ng/ml and TSH ideally should be less than about 2.0. These probelems might go together, or may be independent. Repeating teh prolactin fasting is helpful (if you haven't already done so.). ...Read more

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What does it mean when your f4 thyorid hormone is high and the TSH test is nornmall?

What does it mean when your f4 thyorid hormone is high and the TSH test is nornmall?

Thyroid is normal: T4 can be high with normal thyroid function due to many factors. These factors are eliminated in the free T4 test, but the TSH is most important. Make sure you are taking brand name T4 replacement, as the generics, while cheaper, are unreliable. ...Read more

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My free T4 is high 19.30 pmol/l and my TSH is also high 4.530 mlu/l. What does this mean?

Few possibilities: These labs seem at odds, with TSH suggesting overactive thyroid and ft4 underactive thyroid. Free T4 tests can be inaccurate in some people who have interfering substances present. Another possibility is a tumor in the pituitary secreting too much TSH resulting in thyroid overactivity, and high thyroid hormone levels. This is quite rare, however. Your doctor can help sort this out. ...Read more

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What does this mean? Low henoglobin 129, low MCV 77, low MCH 25. Also have high TSH 10.48, ALT 62.

What does this mean? Low henoglobin 129, low MCV 77, low MCH 25. Also have high TSH 10.48, ALT 62.

Hypothyroid, anemia: Low hemoglobin associated with a low MCV and MCH is usually related to iron deficiency. You should have an iron, tibc, ferritin level done. The high TSH implies a lowthyroid level. You need a free T4 level, and probably a higher dose of synthroid (thyroxine). Significant hypothyroidism can cause iron deficiency anemia, but other causes need to be investigated. The high alt implies a liver problem. ...Read more

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Post thyroidectomy(over a year) show elevated. Tsh. And low. Thyroglobulin. What that means?

Thyroid in the Dumps: There is a possiblity you may not be taking enough thyroid hormone replacement. Your doctor will likely look a little deeper into your thyroid labs to find an answer. ...Read more

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What does normal tsh, but high free T4 mean?

Recheck the labs: Normally, if the ft4 is high, either due to hyperthyroidism or taking too much synthroid, (thyroxine) your TSH is low. Mistakes in labs can occur, so first have them rechecked. Rarely, you can have a pituitary tumor that makes TSH and causes hyperthyroidism, giving you both increased TSH and ft4. But this is rare, and more likely there is a simple explanation. ...Read more

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What does high TSH 5.250 mean when all other bloodwork normal including t4?

What does high TSH  5.250 mean when all other bloodwork normal including t4?

Elevated TSH: Tsh (thyroid stimulating hormone) is produced by the pituitary gland in the brain. When the circulating thyroid hormone (produced by thyroid gland) is insufficient as in hypothyroidism, the TSH goes up. If there is too much circulating thyroid hormone as in hyperthyroidism, the TSH goes way down. So with your elevated tsh, i would guess you are hypothyroid. This is always confusing. Good luck. ...Read more