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Doctor insights on: What Does Hypermetabolic Mean

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What does "hypermetabolic" mean on the report of a pet scan?

What does "hypermetabolic" mean on the report of a pet scan?

Takes up tracer: Pet scans work by imaging a tracer that is a sugar analogue. Since tissue/cells that are more "metabolically active" take up more glucose tracer, we refer to that as "hypermetabolic". Diagnostically, this can mean a number of things and depends on the context. Inflammatory cells and malignant cells (cancer) are typically hypermetabolic. One would have to look at the context and medical history. ...Read more

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Impression on pet CT scan is listed as: follicle on right ovary with associated hypermetabolic activity. What does this mean? Should i be concerned?

Impression on pet CT scan is listed as: follicle on right ovary with associated hypermetabolic activity. What does this mean? Should i be concerned?

Not sure: What really matters is why they did the imaging in the first place. I am going to guess that since you have a history of breast cancer, they were looking for possible distant metastases of this disease. I have personally seen breast cancer spread to the ovaries. If this is their concern, it should be further evaluated. ...Read more

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Recently had pt/ct eyes to thighs, what does hypermetabolic lymph node peak suv 3.5 mean?

Recently had pt/ct eyes to thighs, what does hypermetabolic lymph node peak suv 3.5 mean?

Nonspecific : On FDG pet/ct, hypermetabolic means that there is increased glucose uptake. Increased glucose uptake can be seen in infection, inflammation, or tumor. Suv is a measure of the amount of glucose uptake. Suv of 3.5 is elevated but again, it could be any of the possibilities listed above. How big is the lymph node? Where is it located? Has it been growing? All of these questions are important. ...Read more

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What's the difference between sclerotic and hypermetabolic lesions?

What's the difference between sclerotic and hypermetabolic lesions?

Please see answer: Sclerotic means "hardening" or lack of pliability. An example is arteriosclerosis in which the arteries become hardened due to calcification and scarring(fibrosis). A hypermetabolic lesion is a lesion seen on a PET scan with increased metabolism, such as cancer(which takes up more glucose than normal tissue). A form of glucose is labeled with a radioactive "tracer" and this tracer is seen on PET. ...Read more

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Meaning? 1.1 cm soft tissue density and hypermetabolic activity in deep rt parotid gland, SUV peak 3.7.

Meaning?  1.1 cm soft tissue density and hypermetabolic activity in deep rt parotid gland, SUV peak 3.7.

Possibly malignancy: Any solitary lesion of parotid should be resected with the possibity of malignancy. PET here being positive suggests lesion is cancer but low SUV with peak of 3.7 indicates lower grade malignancy. With possible deep lobe involvement, removing both lobes would require that at time of facial n. dissection that only ophthalmic and ramus be preserved. ...Read more

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Hodgkin lymphoma,stage IIb, bulky. 130mm,after 8 cycle of ABVD, PET + , hypermetabolic mass and increase its size to 141mm! Why?Is Stanford V helpful?

Hodgkin lymphoma,stage IIb, bulky. 130mm,after 8 cycle of ABVD, PET + , hypermetabolic mass and increase its size to 141mm! Why?Is Stanford V helpful?

Jury not out: There is ongoing trial to answer your question but previous studies suggest ABVD superior. That said, factors such as radiotx and personal immune response to Hodgkin D need to be considered. Fail cases to conventional chemoradiotx appear to respond to immune therapy, ie. PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's Lymphoma N Engl J Med 2015; 372:311-319. Confirm ur dx 1st step ...Read more

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NM Pet Report: Abdomen/Pelvis: Persistence of hypermetabolic activity with in rectum, SUV 4.5, compared to prior SUV 5.6. What could its meaning?

NM Pet Report: Abdomen/Pelvis: Persistence of hypermetabolic activity with in rectum, SUV 4.5, compared to prior SUV 5.6. What could its meaning?

Several reasons: Standard uptake value (SUV) GREATER than 2.5 is increased but this is to be correlated with GI evaluations, including presence of polyps, inflammatory dis, diverticulitis or even malignancy. The PCD may need to check if you need Biopsies, if not already done, in the areas where increased sugar uptake seen by PET scan is noted, and one explanation could be resolving inflammation given the decrease. ...Read more

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My mother is 42y and her pet report shows that she have got hypermetabolic lymph nodes.Actually she is a kidney donor can c donate her kidnry or not?

My mother is 42y and her pet report shows that she have got hypermetabolic lymph nodes.Actually she is a kidney donor can c donate her kidnry or not?

Doctors may want...: Doctors may want to evaluate a potential kidney donor to see why she has "hypermetabolic lymph nodes". If no serious medical problem is found, the doctors may feel more comfortable having her as a donor. ...Read more

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Female with mass on sternum. Biopsied 8 years ago benign. I had a pet scan it's hypermetabolic. I have MS and borderline lupus. What are my options?

 Female with mass on sternum. Biopsied 8 years ago benign. I had a pet scan it's hypermetabolic. I have MS and borderline lupus. What are my options?

Sternal mass: Leave it alone unless it has begun enlarging rapidly. I suspect it is one of the several benign hamartomas / developmental anomalies that can happen there and the "hypermetabolism" is marrow. You also have a right and duty to know what the old biopsy showed and what the implications are. ...Read more

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Ct Pet brown fat in neck/ mediastinum near small lymph node difficult to know if node hypermetabolic SUV low in node not enlarged. SIGNIFICANCE?

Ct Pet brown fat in neck/ mediastinum near small lymph node difficult to know if node hypermetabolic  SUV low in node not enlarged. SIGNIFICANCE?

Ultrasound neck: Lymph node small size usually mitigates against neoplasm. An easy way of following lymph node would be ultrasound in a month to see if node enlarges or is stable in size. Tumors usually grow with time. ...Read more